Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Clathrin adaptor complex"'
Autor:
Jonathan G. Hanley
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The precise regulation of AMPA receptor (AMPAR) trafficking in neurons is crucial for excitatory neurotransmission, synaptic plasticity and the consequent formation and modification of neural circuits during brain development and learning. Clathrin-m
Externí odkaz:
https://doaj.org/article/e5cc6bb36dd5468c8dbc502bf70c4069
Publikováno v:
eLife, Vol 7 (2018)
Eukaryotic cells internalize transmembrane receptors via clathrin-mediated endocytosis, but it remains unclear how the machinery underpinning this process is regulated. We recently discovered that membrane-associated muniscin proteins such as FCHo an
Externí odkaz:
https://doaj.org/article/173d1e462426453eb665ef20faeffdbd
Autor:
Ibrahim Nassour, Karolina Brodzik, Hao Zhu, Sotaro Kikuchi, Eunhee Choi, Haishan Gao, Adam C. Yopp, Hongtao Yu, Amit G. Singal
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
Insulin controls glucose homeostasis and cell growth through bifurcated signaling pathways. Dysregulation of insulin signaling is linked to diabetes and cancer. The spindle checkpoint controls the fidelity of chromosome segregation during mitosis. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f92efd86c2afec47c1fdb577a3cc03
http://link.springer.com/article/10.1038/s41467-019-09318-3
http://link.springer.com/article/10.1038/s41467-019-09318-3
Autor:
Gunther Hollopeter, Jeffrey J Lange, Ying Zhang, Thien N Vu, Mingyu Gu, Michael Ailion, Eric J Lambie, Brian D Slaughter, Jay R Unruh, Laurence Florens, Erik M Jorgensen
Publikováno v:
eLife, Vol 3 (2014)
The AP2 clathrin adaptor complex links protein cargo to the endocytic machinery but it is unclear how AP2 is activated on the plasma membrane. Here we demonstrate that the membrane-associated proteins FCHo and SGIP1 convert AP2 into an open, active c
Externí odkaz:
https://doaj.org/article/098d2b93e831478887e9a1475eafe17d
Autor:
Venkatesha Basrur, Nikola Sekulovski, Chien-Wei Lin, Deborah L. Gumucio, Peng Zou, Linnea E. Taniguchi, Sicong Wang, Alexey I. Nesvizhskii, Craig A. Johnson, Jianping Fu, Kenichiro Taniguchi, Amber E. Carleton, Chari L. Cortez, Ryan F. Townshend, Mara C. Duncan
Publikováno v:
Science Advances
APEX2-based spatial proteomics identifies cell polarity proteome of hPSC-cysts, a 3D model of human epiblast cavity formation.
Critical early steps in human embryonic development include polarization of the inner cell mass, followed by formation
Critical early steps in human embryonic development include polarization of the inner cell mass, followed by formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8072fd85283e68b52b3206941e1bf7
http://europepmc.org/articles/PMC8064645
http://europepmc.org/articles/PMC8064645
Autor:
Cheng Zhu, Xuejie Zhou, Ziteng Liu, Hongwei Chen, Hongfeng Wu, Xiao Yang, Xiangdong Zhu, Jing Ma, Hao Dong
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences, Vol 8 (2021)
The clathrin-associated protein adaptin-2 (AP2) is a distinctive member of the hetero-tetrameric clathrin adaptor complex family. It plays a crucial role in many intracellular vesicle transport pathways. The hydroxyapatite (HAp) nanoparticles can ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430612c4f2341b17bed362a865f409c7
https://pubmed.ncbi.nlm.nih.gov/33748189
https://pubmed.ncbi.nlm.nih.gov/33748189
Autor:
Nevan J. Krogan, Andrej Sali, Marissa Suarez, Robyn M. Kaake, Jacob Kress, Peter W. Ramirez, Yonghwa Kwon, Charlotte A. Stoneham, Xiaofei Jia, Ignacia Echeverria, John C. Guatelli, Rajendra Singh
The HIV-1 Nef protein suppresses multiple immune surveillance mechanisms to promote viral pathogenesis and is an attractive target for the development of novel therapeutics. A key function of Nef is to remove the CD4 receptor from the cell surface by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cbde504119a8691879cf094572d956
Publikováno v:
In Vitro Cellular & Developmental Biology - Plant. 54:642-657
Real-time quantitative polymerase chain reaction (RT-qPCR) is an effective method for detecting changes of gene expression in plant cell metabolic regulation. A set of 15 reference gene candidates were selected for the present study of anthocyanin bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7244a40c6a37059dbb0db2f3bbff867
https://doi.org/10.1007/s11627-018-9937-7
https://doi.org/10.1007/s11627-018-9937-7
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
A selenomethionine marker strategy allowed the identification of a region of disconnected electron density at low resolution and despite poor selenomethionine incorporation, thereby building a structural framework for understanding how the clathrin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5856b3e998dadb5c4fd8d6ceb937f9
https://doi.org/10.1107/s2059798315021580
https://doi.org/10.1107/s2059798315021580
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Eukaryotic cells internalize transmembrane receptors via clathrin-mediated endocytosis, but it remains unclear how the machinery underpinning this process is regulated. We recently discovered that membrane-associated muniscin proteins such as FCHo an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7530d4654c37d2b19936514b1bb26278
https://doi.org/10.7554/elife.32242
https://doi.org/10.7554/elife.32242