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pro vyhledávání: '"Class C GPCR"'
Akademický článek
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Publikováno v:
Frontiers in Chemistry, Vol 9 (2022)
Cell-surface receptors play a pivotal role as transducers of extracellular input. Although different cell types express the same receptor, the physiological roles of the receptor are highly dependent on cell type. To understand each role, tactics for
Externí odkaz:
https://doaj.org/article/306bc12b7b1f4ed3af5b57914f996193
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9216 (2022)
The human sweet taste receptor is a heterodimeric receptor composed of two distinct G-protein-coupled receptors (GPCRs), TAS1R2 and TAS1R3. The TAS1R2 and TAS1R3 subunits are members of a small family of class C GPCRs whose members share the same arc
Externí odkaz:
https://doaj.org/article/2a9ad51fd7d546d9a3cf087114832c39
Autor:
Anne M. Roesler, Jovanka Ravix, Colleen M. Bartman, Brijeshkumar S. Patel, Marta Schiliro, Benjamin Roos, Lisa Nesbitt, Christina M. Pabelick, Richard J. Martin, Peter M. MacFarlane, Y. S. Prakash
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Supplemental O2 (hyperoxia), necessary for maintenance of oxygenation in premature infants, contributes to neonatal and pediatric airway diseases including asthma. Airway smooth muscle (ASM) is a key resident cell type, responding to hyperoxia with i
Externí odkaz:
https://doaj.org/article/5535a7aeff7046d5bb61a44eac067e3e
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Mar 01. 114(10), 2568-2573.
Externí odkaz:
https://www.jstor.org/stable/26480070
Autor:
Susumu Tomita
Publikováno v:
Essentials of Cerebellum and Cerebellar Disorders ISBN: 9783031150692
Essentials of Cerebellum and Cerebellar Disorders ISBN: 9783319245492
Essentials of Cerebellum and Cerebellar Disorders ISBN: 9783319245492
Glutamate is a major excitatory neurotransmitter in the vertebrate brain and is utilized at distinct synapses in the cerebellum. Glutamate released from presynaptic terminals binds to various types and classes of glutamate receptors at pre- and posts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e872533b2eaf7d97d6173c3b8e16384
https://doi.org/10.1007/978-3-031-15070-8_30
https://doi.org/10.1007/978-3-031-15070-8_30
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9216
The human sweet taste receptor is a heterodimeric receptor composed of two distinct G-protein-coupled receptors (GPCRs), TAS1R2 and TAS1R3. The TAS1R2 and TAS1R3 subunits are members of a small family of class C GPCRs whose members share the same arc
Publikováno v:
Journal of Molecular Biology. 432:5966-5984
The neurotransmitter γ-aminobutyric acid (GABA) activates the metabotropic GABAB receptor to generate slow, prolonged inhibitory signals that regulate the neural circuitry. The GABAB receptor is an obligate heterodimeric G protein-coupled receptor (
Akademický článek
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Autor:
Cangsong Shen, Chuntao Li, Zhinong Jiang, Qingya Shen, Yan Zhang, Rui Zhou, Li-Nan Chen, Chanjuan Xu, Chunyou Mao, Shenglan Zhang, Jianfeng Liu, Dan-Dan Shen
Publikováno v:
Cell Research. 30:564-573
Metabotropic GABAB G protein-coupled receptor functions as a mandatory heterodimer of GB1 and GB2 subunits and mediates inhibitory neurotransmission in the central nervous system. Each subunit is composed of the extracellular Venus flytrap (VFT) doma