Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Clas Källander"'
Autor:
Jonas Blomberg, Ali Sheikholvaezin, Amal Elfaitouri, Fredrik Blomberg, Anna Sjösten, Johan Mattson Ulfstedt, Rüdiger Pipkorn, Clas Källander, Christina Öhrmalm, Göran Sperber
Publikováno v:
Advances in Virology, Vol 2011 (2011)
Gammaretrovirus-like sequences occur in most vertebrate genomes. Murine Leukemia Virus (MLV) like retroviruses (MLLVs) are a subset, which may be pathogenic and spread cross-species. Retroviruses highly similar to MLLVs (xenotropic murine retrovirus
Externí odkaz:
https://doaj.org/article/675b88ae8ed64472aa9358f9729036b7
Publikováno v:
Journal of Medical Virology. 85:703-708
Drug resistance testing is an important tool in the management of HIV-1 infection. As access to genotypic resistance assays is limited in low- and middle-income settings, alternatives are warranted. The aim of the study was to adapt a phenotypic drug
Autor:
Ali Sheikholvaezin, Rüdiger Pipkorn, Göran O. Sperber, Johan Mattson Ulfstedt, Clas Källander, Anna Sjösten, Jonas Blomberg, Amal Elfaitouri, Fredrik Blomberg, Christina Öhrmalm
Publikováno v:
Advances in Virology
Advances in Virology, Vol 2011 (2011)
Advances in Virology, Vol 2011 (2011)
Gammaretrovirus-like sequences occur in most vertebrate genomes. Murine Leukemia Virus (MLV) like retroviruses (MLLVs) are a subset, which may be pathogenic and spread cross-species. Retroviruses highly similar to MLLVs (xenotropic murine retrovirus
Autor:
Staffan Sjödahl, Anders Malmsten, Xingwu Shao, Ingvar Pettersson, Thomas Leitner, Eric Sandström, Eva-Lena Fredriksson, J. Simon Gronowitz, Clas Källander
Publikováno v:
Journal of Medical Virology. 76:291-296
Reverse transcriptase (RT) is a crucial enzyme for retrovirus replication, and its presence in the virion is indispensable for infectivity. This thesis illustrates the use of RT activity assays as tools for quantitation and characterization of differ
Autor:
Vladimir O. Rechinsky, Sergey N. Kochetkov, Erik Rollman, Anne Kjerrström Zuber, Britta Wahren, Sergey Belikov, Andreas Boberg, Bartek Zuber, Dan Sjöstrand, Maria G. Isaguliants, Clas Källander, Jorma Hinkula, Margaret A. Liu, Ann-Sofie Rytting
Publikováno v:
Vaccine. 22:1810-1819
Drug resistance is becoming a problem in the treatment of the human immunodeficiency virus type one (HIV-1). To obtain therapeutic DNA vaccines that would target multiple drug-resistance (DR) mutations, we cloned genes for DR HIV-1 reverse transcript
Autor:
Thomas Leitner, Eric Sandström, J. Simon Gronowitz, Gary E Corrigan, Anders Malmsten, Clas Källander, Kajsa Aperia, Xingwu Shao
Publikováno v:
Journal of Medical Virology. 71:347-359
Autor:
Anders Sönnerborg, Piotr Nowak, Roger Paredes, Maria Casadellà, Catharina Maijgren Steffensson, Marc Noguera-Julian, Clas Källander, Eva Agneskog
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101508 (2014)
PLoS ONE
PLoS ONE
BACKGROUND: A sensitive, phenotypic reverse transcriptase (RT)-based drug susceptibility assay for the detection of etravirine (ETR) resistance in patient isolates was developed and compared with the results from direct sequencing and ultra-deep pyro
Autor:
R. J.-K. Awad, R. Thorstensson, J. S. Gronowitz, G. E. Corrigan, Clas Källander, D. H. L. Ekstrand
Publikováno v:
Journal of Clinical Microbiology. 35:1080-1089
Standardization and calibration of a new colorimetric assay for detection of reverse transcriptase (RT) was carried out for optimal detection of RT activity-blocking antibody (RTb-Ab) in serum. A total of 99 of 100 Swedish and 54 of 54 African human
Publikováno v:
Antiviral Chemistry and Chemotherapy. 7:313-320
An enzymatic assay based on utilization of one primer/enzyme molecule was specifically designed for evaluation of the chain termination capacity of reverse transcriptase (RT) from HIV-1 isolates. In this assay system (CT assay) there was a 3.2-fold d
Autor:
Johan Lennerstrand, Eric Sandström, J. S. Gronowitz, A. Karlsson, Clas Källander, V. Holmberg, M. Neumüller
Publikováno v:
Journal of Medical Virology. 36:283-291
A new assay for detecting inhibition of reverse transcriptase activity (the RT-i REA) was developed. This assay was standardized for screening serum samples for reverse transcriptase inhibiting antibodies (RT-iAb). High specificity (100%) and sensiti