Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Clarke Stevenson"'
Autor:
Thorfinnur Gunnlaugsson, Thomas McCabe, Paul E. Kruger, Sinead Mulready, Ann-Marie Fanning, R. Jeremy H. Davies, John E. O'Brien, Paul Jensen, Clarke Stevenson
Publikováno v:
Tetrahedron Letters. 46:3761-3766
The cyclen based pyridine complexes 1Ln – 3Ln (Ln = La(III) and Eu(III)) were synthesised as metallo-ribonuclease mimics and their ability to hydrolytically cleave the phosphodiester of HPNP at 37 °C was investigated using UV–vis spectroscopy, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c95f213714263477511a0220883e5df
https://doi.org/10.1016/j.tetlet.2005.03.150
https://doi.org/10.1016/j.tetlet.2005.03.150
Autor:
R. Jeremy H. Davies, John E. O'Brien, Mark Nieuwenhuyzen, Sinead Mulready, Thorfinnur Gunnlaugsson, Clarke Stevenson
Publikováno v:
Polyhedron. 22:711-724
The glycine–alanine conjugated ligands of cyclen (1,4,7,10,-tetraazacyclododecane) 1 and 2, possessing methyl and benzyl alanine esters respectively, and the corresponding lanthanide complexes 1La, 1Eu, 1Tb, 1Yb, 2La, 2Eu, and 2Tb were designed wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b56bcd45e654899ae92f95dc2ff1ef4
https://doi.org/10.1016/s0277-5387(02)01402-x
https://doi.org/10.1016/s0277-5387(02)01402-x
Autor:
Mark Lawler, R. Jeremy H. Davies, Clare M. O'Keeffe, Yvonne Kavanagh, Peter H. Boyle, Clarke Stevenson, John M. Kelly, Conor W. Crean
Publikováno v:
Photochemical & Photobiological Sciences. 1:1024-1033
Photooxidative damage was induced predominantly at a single guanine base in a target DNA by irradiation (lambda > 330 nm) in the presence of complementary oligodeoxynucleotide conjugates (ODN-5'-linker-[Ru(phen)3]2+) (phen = 1,10-phenanthroline). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac1f4ac8265cbf50995a86b7c09afc4
https://doi.org/10.1039/b207387k
https://doi.org/10.1039/b207387k
Publikováno v:
Photochemistry and Photobiology. 59:197-203
Gel sequencing experiments with the 5′- and 3′-end-labeled oligonucleotides d(A3GA4GA5GA6GA3G) and d(AT) 10 have demonstrated that dimeric adenine photoproducts and thymine-adenine photoadducts constitute alkali-labile lesions in UV-irradiated DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5558c095ee840a5bc543e49ed40465a
https://doi.org/10.1111/j.1751-1097.1994.tb05022.x
https://doi.org/10.1111/j.1751-1097.1994.tb05022.x
Autor:
Bridget K. Stein, Clarke Stevenson, Derek R. Boyd, Shiv Kumar, Narain D. Sharma, John F. Malone, R. Jeremy H. Davies, Lisa Cosby, Ann P. Hunter, Jason Lyle
Publikováno v:
ChemInform. 33
Treatment of guanosine or 2′-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5758f7f5f2c36da7aa655745fdf42fc
https://doi.org/10.1002/chin.200243144
https://doi.org/10.1002/chin.200243144
Publikováno v:
Biochemical and Biophysical Research Communications. 169:87-94
From gel sequencing experiments with 32 P-end-labelled oligodeoxyribonucleotides, it is shown that treatment of DNA with the powerful oxidant dimethyldioxirane, followed by heating in piperidine, causes selective strand scission at the sites of guani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5e0660e1032a449bfdf20180945a38
https://doi.org/10.1016/0006-291x(90)91437-w
https://doi.org/10.1016/0006-291x(90)91437-w
Autor:
Clarke Stevenson, Michael G. B. Drew, Paul C. Yates, Charles J. Harding, Jane Nelson, Suman Raghunathan, Debbie McDowell
Publikováno v:
J. Chem. Soc., Dalton Trans.. :2521-2533
Using a set of macrocyclic ligands 8,12;21,25-dinitrilo-1,6,14,19-tetra-azacyclohexacosa-1 (26),6,8,10,13,19,22,24-octaene (L1), 7,11; 19,23-dinitrilo-1,5,13,17-tetra-azacyclotetracosa-1 (24),5,7,9,12,17,20,22-octaene (L2), and 7,10;18,21 -diepoxy-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36d8b0a7349ddc31fa1756dbd701fed4
https://doi.org/10.1039/dt9900002521
https://doi.org/10.1039/dt9900002521
Autor:
Russell Camier, John M. Kelly, Conor W. Crean, Clarke Stevenson, Mark Lawler, R. Jeremy H. Davies, Peter H. Boyle
Publikováno v:
Organicbiomolecular chemistry. 2(24)
Two 17-mer oligodeoxynucleotide-5′-linked-(6,7-diphenylpterin) conjugates, 2 and 3, were prepared as photosensitisers for targeting photooxidative damage to a 34-mer DNA oligodeoxynucleotide (ODN) fragment 1 representing the chimeric bcr–abl gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5062f1099de47571f05fc65ed80b38
https://pubmed.ncbi.nlm.nih.gov/15592617
https://pubmed.ncbi.nlm.nih.gov/15592617
Autor:
Lisa Cosby, Narain D. Sharma, Bridget K. Stein, Shiv Kumar, John F. Malone, Ann P. Hunter, Derek R. Boyd, Clarke Stevenson, R. Jeremy H. Davies, Jason Lyle
Publikováno v:
ChemInform. 35
Final oxidation products generated from guanosine and 2'-deoxyguanosine by reaction with dimethyldioxirane have been identified as 4-amidinocarbamoyl-5-hydroxyimidazoles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9246f1b06cb90fcdf05c580db738117d
https://doi.org/10.1002/chin.200407246
https://doi.org/10.1002/chin.200407246
Autor:
Jason Lyle, Bridget K. Stein, Clarke Stevenson, Shiv Kumar, Derek R. Boyd, Lisa Cosby, John F. Malone, Ann P. Hunter, Narain D. Sharma, R. Jeremy H. Davies
Publikováno v:
Chemical Communications. :1378-1379
Treatment of guanosine or 2′-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3663e973fd9fbf4d168bb577ba7cef4
https://doi.org/10.1039/b201418c
https://doi.org/10.1039/b201418c