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pro vyhledávání: '"Clarke,RJ"'
Cholesterol's effects on Na+,K+-ATPase reconstituted in phospholipid vesicles have been extensively studied. However, previous studies have reported both cholesterol-mediated stimulation and inhibition of Na+,K+-ATPase activity. Here, using partial r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::fd1d70d14841d316922a059d23ce7503
https://hdl.handle.net/10453/140783
https://hdl.handle.net/10453/140783
Bacterial colonization and biofilm development on medical devices can lead to infection. Antimicrobial peptide-coated surfaces may prevent such infections. Melimine and Mel4 are chimeric cationic peptides showing broad-spectrum antimicrobial activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::41969e6c4dc1aba0c5c16ca0477516f0
https://hdl.handle.net/10453/146582
https://hdl.handle.net/10453/146582
Autor:
Chen, Z-M, Iona, A, Parish, SE, Chen, Y, Guo, Y, Bragg, FJ, Yang, L, Bian, Z, Holmes, MV, Lewington, SL, Lacey, BWH, Gao, R, Liu, F, Zhang, Z, Chen, J, Walters, RG, Collins, RE, Clarke, RJ, Peto, R, Li, L
Background China has high stroke rates despite the population being relatively lean. Uncertainty persists about the relevance of adiposity to risk of stroke types. Methods The China Kadoorie Biobank enrolled 512,891 adults aged 30-79 years from 10 ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d41bd04a514836b995f2698e754c3fb7
https://ora.ox.ac.uk/objects/uuid:7bf5cb69-80b6-4869-9a6c-9fb8da2b2af3
https://ora.ox.ac.uk/objects/uuid:7bf5cb69-80b6-4869-9a6c-9fb8da2b2af3
Autor:
Lu, L, Bennett, D, Millwood, I, Parish, S, McCarthy, M, Mahajan, A, Lin, X, Bragg, F, Guo, Y, Holmes, M, Azfal, S, Nordestgaard, B, Bian, Z, Hill, M, Walters, R, Li, ZL, Chen, Z, Clarke, RJ
Background: Observational studies have reported that higher plasma 25-hydroxy vitamin D (25[OH]D) concentrations are associated with lower risks of diabetes, but it is unclear if these associations are causal. The aim of this study was to test the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8c2b74f540d1a88fd339c656148a5bc0
https://doi.org/10.1371/journal.pmed.1002566
https://doi.org/10.1371/journal.pmed.1002566
Autor:
Kurmi, OP, Davis, K, Lam, KBH, Guo, Y, Vaucher, J, Bennett, D, Wang, J, Bian, Z, Du, H, Li, L, Clarke, RJ, Chen, Z
Introduction Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide; with COPD deaths in China accounting for one-third of all such deaths. However, there is limited available evidence on the management of COPD in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c59c5e6b3d5189486bbf0b806c5696cf
https://doi.org/10.1136/bmjresp-2017-000267
https://doi.org/10.1136/bmjresp-2017-000267
Autor:
Holmes, MV, Millwood, IY, Kartsonaki, C, Hill, MR, Bennett, DA, Boxall, R, Guo, Y, Xu, X, Bian, Z, Hu, R, Walters, RG, Chen, J, Ala-Korpela, M, Parish, SE, Clarke, RJ, Peto, R, Collins, RE, Li, L, Chen, Z
Background Blood lipids are established risk factors for myocardial infarction (MI), but uncertainty persists about the relevance of lipids, lipoprotein particles and circulating metabolites for MI and stroke subtypes. Objectives To investigate the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d6c8a663263e713b42268ecae9ec8417
https://ora.ox.ac.uk/objects/uuid:26298223-b5bf-4d36-91b4-b7a5d5536d31
https://ora.ox.ac.uk/objects/uuid:26298223-b5bf-4d36-91b4-b7a5d5536d31
Autor:
Millwood, IY, Bennett, D, Holmes, MV, Boxall, R, Guo, Y, Bian, Z, Yang, L, Sansome, GS, Chen, Y, Huaidong, D, Yu, C, Hacker, A, Reilly, D, Tan, Y, Hill, MR, Chen, J, Peto, R, Shen, H, Collins, RE, Clarke, RJ, Li, L, Walters, R, Chen, Z
Importance Raising HDL-cholesterol through pharmacological inhibition of cholesteryl ester transfer protein is a potentially important strategy for prevention and treatment of cardiovascular diseases. Objective To use genetic variants in the CETP gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::404732c25274b626f0fb0b266dd1a996
https://ora.ox.ac.uk/objects/uuid:3ec114de-b84e-4e4c-a9bb-c462f7708a47
https://ora.ox.ac.uk/objects/uuid:3ec114de-b84e-4e4c-a9bb-c462f7708a47
© 2017 Elsevier B.V. RH421 is a voltage-sensitive fluorescent styrylpyridinium dye which has often been used to probe the kinetics of Na+,K+-ATPase partial reactions. The origin of the dye's response has up to now been unclear. Here we show that RH4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::1c8e3b359793215232bbd8bb648bf0c4
https://hdl.handle.net/10453/123981
https://hdl.handle.net/10453/123981
Autor:
Nelson,CP, Hamby,SE, Saleheen,D, Hopewell,JC, Zeng,L, Assimes,TL, Kanoni,S, Willenborg,C, Burgess,S, Amouyel,P, Anand,S, Blankenberg,S, Boehm,BO, Clarke,RJ, Collins,R, Dedoussis,G, Farrall,M, Franks,PW, Groop,L, Hall,AS, Hamsten,A, Hengstenberg,C, Hovingh,GK, Ingelsson,E, Kathiresan,S, Kee,F, König,IR, Kooner,J, Lehtimäki,T, März,W, McPherson,R, Metspalu,A, Nieminen,MS, O'Donnell,CJ, Palmer,CN, Peters,A, Perola,M, Reilly,MP, Ripatti,S, Roberts,R, Salomaa,V, Shah,SH, Schreiber,S, Siegbahn,A, Thorsteinsdottir,U, Veronesi,G, Wareham,N, Willer,CJ, Zalloua,PA, Erdmann,J, Deloukas,P, Watkins,H, Schunkert,H, Danesh,J, Thompson,JR, Samani,NJ, Assimes,T, Goldstein,BA, Stirrups,K, Cazier,JB, Johansson,Å, Lee,JY, Chambers,JC, Esko,T, Folkersen,L, Goel,A, Grundberg,E, Havulinna,AS, Ho,WK, Eriksson,N, Kleber,ME, Kristiansson,K, Lundmark,P, Lyytikäinen,LP, Rafelt,S, Shungin,D, Strawbridge,RJ, Thorleifsson,G, Tikkanen,E, Van, Zuydam, N, Voight,BF, Waite,LL, Zhang,W, Ziegler,A, Absher,D, Altshuler,D, Balmforth,AJ, Barroso,I, Braund,PS, Burgdorf,C, Claudi Boehm,S, Cox,D, Dimitriou,M, Do,R, Doney,AS, El, Mokhtari, Eriksson,P, Fischer,K, Fontanillas,P, Franco Cereceda,A, Gigante,B, Gustafsson,S, Hager,J, Hallmans,G, Han,BG, Hunt,SE, Kang,HM, Illig,T, Kessler,T, Knowles,JW, Kolovou,G, Kuusisto,J, Langenberg,C, Langford,C, Leander,K, Lokki,ML, Lundmark,A, McCarthy,MI, Meisinger,C, Melander,O, Mihailov,E, Maouche,S, Morris,AD, Müller Nurasyid,M, Nikus,K, Peden,JF, Rayner,NW, Rasheed,A, Rosinger,S, Rubin,D, Rumpf,MP, Schäfer,A, Sivananthan,M, Song,C, Stewart,AF, Tan,ST, Thorgeirsson,G, van, der, Schoot, CE, Wagner,PJ, Wells,GA, Wild,PS, Yang,TP, Arveiler,D, Basart,H, Boehnke,M, Boerwinkle,E, BRAMBILLA, PAOLO, Cambien,F, Cupples,AL, de, Faire, U, Dehghan,A, Diemert,P, Epstein,SE, Evans,A, Ferrario,MM, Ferrières,J, Gauguier,D, Go,AS, Goodall,AH, Gudnason,V, Hazen,SL, Holm,H, Iribarren,C, Jang,Y, Kähönen,M, Kim,HS, Klopp,N, Koenig,W, Kratzer,W, Kuulasmaa,K, Laakso,M, Laaksonen,R, Lind,L, Ouwehand,WH, Parish,S, Park,JE, Pedersen,NL, Quertermous,T, Rader,DJ, Schadt,E, Sinisalo,J, Stark,K, Stefansson,K, Trégouët,DA, Virtamo,J, Wallentin,L, Zimmermann,ME, Sandhu,MS, Pastinen,T, Syvänen,AC, Blankenberg,SS, Clarke,R, O'Donnell,C, Kooner,JS
Publikováno v:
New England Journal of Medicine; 372(17), pp 1608-1618 (2015)
New England journal of medicine, 372(17), 1608-1618. Massachussetts Medical Society
New England journal of medicine, 372(17), 1608-1618. Massachussetts Medical Society
BACKGROUND: The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS: We used a genetic approach to investigate the association between height and CAD, usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f7f0cf42b8ea318d0434af2586dc6a
https://lup.lub.lu.se/record/5386538
https://lup.lub.lu.se/record/5386538
Publikováno v:
Noske, R, Cornelius, F & Clarke, RJ 2010, ' Investigation of the enzymatic activity of the Na +,K +-ATPase via isothermal titration microcalorimetry ', B B A-Biomembranes, vol. 1797, pp. 1540-1545 .
Udgivelsesdato: Mar 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::7e31c24ebfab8390f6e147a82eb5f938
https://pure.au.dk/portal/da/publications/investigation-of-the-enzymatic-activity-of-the-nakatpase-via-isothermal-titration-microcalorimetry(1cb313a0-72fb-11df-8c1a-000ea68e967b).html
https://pure.au.dk/portal/da/publications/investigation-of-the-enzymatic-activity-of-the-nakatpase-via-isothermal-titration-microcalorimetry(1cb313a0-72fb-11df-8c1a-000ea68e967b).html