Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Clark RO"'
Autor:
Bingxian Xu, Dae-Sung Hwangbo, Sumit Saurabh, Clark Rosensweig, Ravi Allada, William L Kath, Rosemary Braun
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 4, p e1012029 (2024)
The circadian clock is an evolutionarily-conserved molecular oscillator that enables species to anticipate rhythmic changes in their environment. At a molecular level, the core clock genes induce circadian oscillations in thousands of genes in a tiss
Externí odkaz:
https://doaj.org/article/edd254007220489a847b0e912a4e4382
Autor:
Clark Roberts, Barbara J. Sahakian, Shuquan Chen, Samantha N. Sallie, Clare Walker, Simon R. White, Jochen Weber, Nikolina Skandali, Trevor W. Robbins, Graham K. Murray
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Functional impairments in cognition are frequently thought to be a feature of individuals with depression or anxiety. However, documented impairments are both broad and inconsistent, with little known about when they emerge, whether they are
Externí odkaz:
https://doaj.org/article/9d498e30eb9c4a2fb793f8b720e8e577
Autor:
Clark Roberts, Annemieke M. Apergis-Schoute, Annette Bruhl, Magda Nowak, David S. Baldwin, Barbara J. Sahakian, Trevor W. Robbins
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Avoidance and heightened responses to perceived threats are key features of anxiety disorders. These disorders are characterised by inflexibility in dynamically updating behavioural and physiological responses to aversively conditioned cues
Externí odkaz:
https://doaj.org/article/19108da3d90940e89bcfd6c0888221e1
Autor:
Tomas Andreani, Clark Rosensweig, Shiju Sisobhan, Emmanuel Ogunlana, William Kath, Ravi Allada
Publikováno v:
eLife, Vol 11 (2022)
Homeostatic and circadian processes collaborate to appropriately time and consolidate sleep and wake. To understand how these processes are integrated, we scheduled brief sleep deprivation at different times of day in Drosophila and find elevated mor
Externí odkaz:
https://doaj.org/article/a30b30deda2246d4bcc471aa54b92817
Autor:
James A. Ridout, Neil P. Barton, Matthew A. Janiga, Carolyn A. Reynolds, Jackie C. May, Clark Rowley, Craig H. Bishop
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 13, Iss 4, Pp n/a-n/a (2021)
Abstract A simple parameter nudging procedure is described that systematically reduces near‐analysis time errors in the surface net shortwave flux in the Navy ESPC (Earth System Prediction Capability) system, a global coupled forecast system that i
Externí odkaz:
https://doaj.org/article/a9a9c153f7574a1e959f5d34e8bcc36e
Autor:
Neil Barton, E. Joseph Metzger, Carolyn A. Reynolds, Benjamin Ruston, Clark Rowley, Ole Martin Smedstad, James A. Ridout, Alan Wallcraft, Sergey Frolov, Patrick Hogan, Matthew A. Janiga, Jay F. Shriver, Justin McLay, Prasad Thoppil, Andrew Huang, William Crawford, Timothy Whitcomb, Craig H. Bishop, Luis Zamudio, Michael Phelps
Publikováno v:
Earth and Space Science, Vol 8, Iss 4, Pp n/a-n/a (2021)
Abstract This paper describes the new global Navy Earth System Prediction Capability (Navy‐ESPC) coupled atmosphere‐ocean‐sea ice prediction system developed at the Naval Research Laboratory (NRL) for operational forecasting for timescales of d
Externí odkaz:
https://doaj.org/article/4e70c63f8aeb4b958ec5a10fb0e13497
Autor:
Clark Rosensweig, Kimberly A. Reynolds, Peng Gao, Isara Laothamatas, Yongli Shan, Rama Ranganathan, Joseph S. Takahashi, Carla B. Green
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The molecular mechanisms that define the periodicity or rate of the circadian clock are not well understood. Here the authors use a multidisciplinary approach and identify a mechanism for period regulation that depends on the affinity of the core clo
Externí odkaz:
https://doaj.org/article/65074cf0d73e41918a1780ff7d99d766
Autor:
Clark Rowley, Andrea Mask
Publikováno v:
Oceanography, Vol 27, Iss 3, Pp 44-55 (2014)
The US Navy maintains a capability for regional and coastal ocean modeling as part of a comprehensive effort to predict the impact of the environment (air, water, land, and ice) on naval operations, training, and support activities. The current opera
Externí odkaz:
https://doaj.org/article/48643065bb0a40ffaf0bf3a149ac1421
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Traumatic brain injury (TBI) is a widespread epidemic with severe cognitive, affective, and behavioral consequences. TBIs typically result in a relatively rapid inflammatory and neuroinflammatory response. A major component of the neuroinflammatory r
Externí odkaz:
https://doaj.org/article/3908717640be4706b6e900e2e15b6980
Autor:
Clark Robert D.
Publikováno v:
Journal of the Brazilian Chemical Society, Vol 13, Iss 6, Pp 788-794 (2002)
A great deal of effort is currently going into the design of combinatorial libraries. Published approaches are generally "optimal" in that each best satisfies the target objective function it employs. Relative efficiencies can be compared in such cas
Externí odkaz:
https://doaj.org/article/81c222205e8d40e8a6058b1c2a780774