Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Clark L. Gross"'
Publikováno v:
Toxicology Mechanisms and Methods. 14:317-322
Sulfur mustard (SM) is a potent alkylating agent, profoundly cytotoxic, and a powerful vesicant. SM reacts quite extensively with glutathione (GSH) and forms GSH conjugates, which are presumably excreted through the mercapturic acid pathway in mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feaf75bf87a79f0208a37d8334a57173
https://doi.org/10.1080/15376520490434601
https://doi.org/10.1080/15376520490434601
Publikováno v:
Toxicology Mechanisms and Methods. 13:263-268
Sulfur mustard (SM) is a potent vesicating agent that has pronounced cytotoxic effects as well as mutagenic, carcinogenic, and radiomimetic properties. Isolated human peripheral blood lymphocytes (PBLs) and human epidermal keratinocytes (HEKs) have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d42722ba58f3d915e682ca468eef4fd
https://doi.org/10.1080/713857190
https://doi.org/10.1080/713857190
Publikováno v:
Cell Biology and Toxicology. 13:167-173
Sulfur mustard (HD, mustard gas) is a vesicant chemical warfare agent for which there is no specific medical countermeasure. A potential approach to combating the debilitating effects of this agent is the use of compounds that can react with this mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99548043af235348d1508e619c9f596c
https://doi.org/10.1023/a:1007354127919
https://doi.org/10.1023/a:1007354127919
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 12:337-347
Sulfur mustard is an alkylating agent that causes severe, potentially debilitating blisters following cutaneous exposure. Its mechanism of pathogenesis is unknown and no antidote exists. The biochemical basis of sulfur mustard's vesicating activity h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25acfb0447c46a9da25e392b7a11c7b9
https://doi.org/10.3109/15569529309050150
https://doi.org/10.3109/15569529309050150
Publikováno v:
Cell Biology and Toxicology. 9:259-267
Glutathione (GSH) is the major nonprotein thiol that can protect cells from damage due to electrophilic alkylating agents by forming conjugates with the agent. Sulfur mustard (HD) is an electrophilic alkylating agent that has potent mutagenic, carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749f1ef90cd0a32c051fa25b0f58333e
https://doi.org/10.1007/bf00755604
https://doi.org/10.1007/bf00755604
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 11:293-304
Human epidermal keratinocytes (HEK), human epithelial tumor cells (HeLa), and actively proliferating human peripheral blood lymphocytes (PBL) were used as in vitro model systems to investigate the biochemical sequelae of sulfur mustard-induced injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ac88285242e2bd219a9bb4fc94427b
https://doi.org/10.3109/15569529209042723
https://doi.org/10.3109/15569529209042723
Publikováno v:
Cutaneous and ocular toxicology. 25(3)
Sulfur mustard (SM) is a powerful cytotoxic agent as well as a potent vesicant, mutagen, and carcinogen. This compound reacts with glutathione (GSH) and forms GSH-SM conjugates that appear to be excreted through the mercapturic acid pathway in mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196b9d96053c78249533cd4e7d8b553d
https://pubmed.ncbi.nlm.nih.gov/16980241
https://pubmed.ncbi.nlm.nih.gov/16980241
Autor:
Clark L. Gross, Offie Clark, William J. Smith, Janet Moser, Juanita J. Guzman, Bethany Toliver, Eric W. Nealley
Publikováno v:
Alternative Toxicological Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7a6e4eb7448ae2ccfc8659219c8dba2
https://doi.org/10.1201/9780203008799.ch26
https://doi.org/10.1201/9780203008799.ch26
Publikováno v:
Alternative Toxicological Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24034ba03125c48f97060c6585b22c4a
https://doi.org/10.1201/9780203008799.ch24
https://doi.org/10.1201/9780203008799.ch24
Publikováno v:
Alternative Toxicological Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e8562dec6dd3dad73121f93632740f4
https://doi.org/10.1201/9780203008799.ch25
https://doi.org/10.1201/9780203008799.ch25