Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Clark K Colton"'
Autor:
Klearchos K Papas, Melena D Bellin, David E R Sutherland, Thomas M Suszynski, Jennifer P Kitzmann, Efstathios S Avgoustiniatos, Angelika C Gruessner, Kathryn R Mueller, Gregory J Beilman, Appakalai N Balamurugan, Gopalakrishnan Loganathan, Clark K Colton, Maria Koulmanda, Gordon C Weir, Josh J Wilhelm, Dajun Qian, Joyce C Niland, Bernhard J Hering
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134428 (2015)
BackgroundReliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular ox
Externí odkaz:
https://doaj.org/article/3b1106a0d9a04b4484572e0579606e02
Autor:
Tova Neufeld, Barbara Ludwig, Uriel Barkai, Gordon C Weir, Clark K Colton, Yoav Evron, Maria Balyura, Karina Yavriyants, Baruch Zimermann, Dmitri Azarov, Shiri Maimon, Noa Shabtay, Tania Rozenshtein, Dana Lorber, Anja Steffen, Udi Willenz, Konstantine Bloch, Pnina Vardi, Ran Taube, Paul de Vos, Eli C Lewis, Stefan R Bornstein, Avi Rotem
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70150 (2013)
Developing a device that protects xenogeneic islets to allow treatment and potentially cure of diabetes in large mammals has been a major challenge in the past decade. Using xenogeneic islets for transplantation is required in light of donor shortage
Externí odkaz:
https://doaj.org/article/507f48e4512a477a89413d366194a361
Publikováno v:
Springer International Publishing
Cell Mol Bioeng
Cell Mol Bioeng
Introduction Residual pluripotent stem cells (PSC) within differentiated populations are problematic because of their potential to form tumors. Simple methods to reduce their occurrence are needed. Methods Here, we demonstrate that control of the oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e904fbb4a95efcad056f7df0d356d1fe
https://doi.org/10.1007/s12195-021-00687-8
https://doi.org/10.1007/s12195-021-00687-8
Autor:
Uriel Barkai Ph.D., Gordon C. Weir, Clark K. Colton, Barbara Ludwig, Stefan R. Bornstein, Mathias D. Brendel, Tova Neufeld, Chezi Bremer, Assaf Leon, Yoav Evron, Karina Yavriyants, Dimitri Azarov, Baruch Zimermann, Shiri Maimon, Noa Shabtay, Maria Balyura, Tania Rozenshtein, Pnina Vardi, Konstantin Bloch, Paul De Vos, Avi Rotem
Publikováno v:
Cell Transplantation, Vol 22 (2013)
The current epidemic of diabetes with its overwhelming burden on our healthcare system requires better therapeutic strategies. Here we present a promising novel approach for a curative strategy that may be accessible for all insulin-dependent diabete
Externí odkaz:
https://doaj.org/article/16b3b5a5d3cc465aa8cfdf841bc10acf
Autor:
William Dalzell, Rae Jean N. Wiggins, Nishikant Sonwalkar, Michael C. Kutney, Clark K. Colton, Bonnie Burrell
Publikováno v:
2000 Annual Conference Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc197f7dac7de4731addc3fb81a13363
https://doi.org/10.18260/1-2--8679
https://doi.org/10.18260/1-2--8679
Autor:
Zhi-Guo Su, Clark K. Colton
Publikováno v:
Protein Purification Process Engineering ISBN: 9780203741733
A variety of Microfiltration (MF) and Ultrafiltration (UF) membranes and crossflow filtration modules are marketed by filter manufacturers around the world. Conventional filtration, in which relatively coarse particles are separated from a fluid usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8371f56fc20447405ecf582209a36868
https://doi.org/10.1201/9780203741733-4
https://doi.org/10.1201/9780203741733-4
Autor:
Clark K. Colton, Arun Sharma, Habib Rezanejad, Anthony N. Hollenberg, Preeti Ramadoss, Ann Marie Zavacki, Susan Bonner-Weir, Thomas S. Scanlan, Michelle Matzko, P. Reed Larsen, Cristina Aguayo-Mazzucato, Amanda R. Diienno, Terence B. Lee
Previously, we showed that thyroid hormone (TH) triiodothyronine (T(3)) enhanced β-cell functional maturation through induction of Mafa. High levels of T(3) have been linked to decreased life span in mammals and low levels to lengthened life span, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c262e810e2b70d870dfe6342a46bb51
https://europepmc.org/articles/PMC6014556/
https://europepmc.org/articles/PMC6014556/
Autor:
Christopher Cahill, Clark K. Colton, Jennifer Hollister-Lock, Amanda R. Diienno, Susan Bonner-Weir, Gordon C. Weir, Arun Sharma, Cristina Aguayo-Mazzucato
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:3651-3659
Context: Human embryonic stem cells (hESCs) differentiated toward β-cells and fetal human pancreatic islet cells resemble each other transcriptionally and are characterized by immaturity with a lack of glucose responsiveness, low levels of insulin c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db68e6ff811876a8a8d31450a6ac099f
https://doi.org/10.1210/jc.2015-2632
https://doi.org/10.1210/jc.2015-2632
Autor:
F. J. Kaup, Martina Bleyer, Stefan R. Bornstein, Uriel Barkai, Avi Rotem, Stefan Ludwig, Susann Lehmann, Anja Steffen, Clark K. Colton, Yvonne Knauf, Barbara Ludwig, Baruch Zimerman, Uwe Schönmann, Janine Schmid, Undine Schubert, Yuval Avni, Ezio Bonifacio, Michele Solimena, Sophie Heinke, Andrew V. Schally, Helena Grinberg-Rashi, Andreas Reichel, Peter M. Jones
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 114, 11745-11750 (2017)
Significance Diabetes mellitus type 1 is an autoimmune disease that results in irreversible destruction of insulin-producing beta cells. Substantial advances have been made in beta cell replacement therapies during the last decades. However, lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fde080bf3326682e2574c10df93b8c
https://www.zora.uzh.ch/id/eprint/208308/
https://www.zora.uzh.ch/id/eprint/208308/
Autor:
Andreas Reichel, Michele Solimena, Stefan R. Bornstein, Norman L. Block, Anja Steffen, Uriel Barkai, Barbara Ludwig, Clark K. Colton, Zohar Gendler, Ezio Bonifacio, Avi Rotem, Andrew V. Schally, Stefan Ludwig, Baruch Zimerman, Stephan Kersting
Publikováno v:
Proceedings of the National Academy of Sciences. 110:19054-19058
Significance Diabetes mellitus type 1 is an autoimmune disease that results in irreversible destruction of insulin-producing beta cells. Substantial advances have been made in beta cell replacement therapies over the last decades. However, lack of el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb73386c6493aa585031fc2709e25dd
https://doi.org/10.1073/pnas.1317561110
https://doi.org/10.1073/pnas.1317561110