Zobrazeno 1 - 10
of 534
pro vyhledávání: '"Clark C, Chen"'
Autor:
Lindsey Greenlund, Ryan Shanley, Kellen Mulford, Elizabeth C. Neil, Jessica Lawrence, Susan Arnold, Michael Olin, G. Elizabeth Pluhar, Andrew S. Venteicher, Clark C. Chen, Clara Ferreira, Margaret Reynolds, L. Chinsoo Cho, Christopher Wilke, B. Aika Shoo, Jianling Yuan, Kathryn Dusenbery, Lawrence R. Kleinberg, Stephanie A. Terezakis, Lindsey Sloan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTreatment for glioblastomas, aggressive and nearly uniformly fatal brain tumors, provide limited long-term success. Immunosuppression by myeloid cells in both the tumor microenvironment and systemic circulation are believed to contribute
Externí odkaz:
https://doaj.org/article/d1f68d365a3b44f692c9eb36b746cbf0
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 36, Iss , Pp 100859- (2023)
Among children and adolescents in the United States (0 to 19 years old), brain and other central nervous system tumors are the second most common types of cancers, surpassed in incidence only by leukemias. Despite significant progress in the diagnosi
Externí odkaz:
https://doaj.org/article/7fb2034347644df38bc3bad01a3866b3
Publikováno v:
Journal of Central Nervous System Disease, Vol 15 (2023)
We examined the efficacy of vagal nerve stimulation (VNS) for patients suffering from medically intractable epilepsy. Four randomized controlled trials (RCTs - 3 adult RCTs and 1 pediatric RCT) were identified in our comprehensive literature search.
Externí odkaz:
https://doaj.org/article/8e9b1e2617714bab82df197779e9dc62
Autor:
Samuel W. Cramer, Samuel P. Haley, Laurentiu S. Popa, Russell E. Carter, Earl Scott, Evelyn B. Flaherty, Judith Dominguez, Justin D. Aronson, Luke Sabal, Daniel Surinach, Clark C. Chen, Suhasa B. Kodandaramaiah, Timothy J. Ebner
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105943- (2023)
>2.5 million individuals in the United States suffer mild traumatic brain injuries (mTBI) annually. Mild TBI is characterized by a brief period of altered consciousness, without objective findings of anatomic injury on clinical imaging or physical de
Externí odkaz:
https://doaj.org/article/e7f3a0402c7140308a4ea550cb0c070f
Autor:
Kellen Mulford, Chuyu Chen, Kathryn Dusenbery, Jianling Yuan, Matthew A. Hunt, Clark C. Chen, Paul Sperduto, Yoichi Watanabe, Christopher Wilke
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 29, Iss , Pp 27-32 (2021)
Purpose: Adjuvant radiosurgery to the cavities of surgically resected brain metastases provides excellent local tumor control while reducing the risk of deleterious cognitive decline associated with whole brain radiotherapy. A subset of these patient
Externí odkaz:
https://doaj.org/article/2977a3e760074092a0303755672151a1
Autor:
Antonietta Canna, Lauri J. Lehto, Lin Wu, Sheng Sang, Hanne Laakso, Jun Ma, Pavel Filip, Yuan Zhang, Olli Gröhn, Fabrizio Esposito, Clark C. Chen, Igor Lavrov, Shalom Michaeli, Silvia Mangia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury. Despite significant positive impact of ESCS, currently available protocols
Externí odkaz:
https://doaj.org/article/b04de9cae18847f2a2d23a54939206e5
Autor:
Xiaoting Yu, Jing Jin, Yanwen Zheng, Hua Zhu, Hui Xu, Jun Ma, Qing Lan, Zhixiang Zhuang, Clark C. Chen, Ming Li
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-11 (2021)
Abstract Guanylate binding proteins (GBPs), a family of interferon-inducible large GTPase, play a pivotal role in cell-autonomous immunity and tumor malignant transformation. Glioblastoma (GBM) is the most prevalent and lethal primary brain tumor in
Externí odkaz:
https://doaj.org/article/14012d7d220244259e9dda501ae4b5b2
Autor:
Birra R. Taha, Christian R. Osswald, Matthew Rabon, Carolina Sandoval Garcia, Daniel J. Guillaume, Xiao Wong, Andrew S. Venteicher, David P. Darrow, Michael C. Park, Robert A. McGovern, Cornelius H. Lam, Clark C. Chen
Publikováno v:
World Neurosurgery: X, Vol 13, Iss , Pp 100115- (2022)
Background: The ClearPoint neuronavigation system affords real-time magnetic resonance imaging (MRI) guidance during stereotactic procedures. While such information confers potential clinical benefits, additional operative time may be needed. Methods
Externí odkaz:
https://doaj.org/article/13ae98fd746b4a93913c196b7f32039c
Publikováno v:
International Journal of Hyperthermia, Vol 37, Iss 2, Pp 61-67 (2020)
Background Stereotactic laser ablation(SLA) or laser interstitial thermal therapy (LITT) has been increasingly adopted as a treatment for primary and metastatic brain cancers. Here, we examined the published economic assessments of SLA, and review th
Externí odkaz:
https://doaj.org/article/d86fab8a150842ffb768f4d18b0087a8
Autor:
Tomoyuki Koga, Isaac A. Chaim, Jorge A. Benitez, Sebastian Markmiller, Alison D. Parisian, Robert F. Hevner, Kristen M. Turner, Florian M. Hessenauer, Matteo D’Antonio, Nam-phuong D. Nguyen, Shahram Saberi, Jianhui Ma, Shunichiro Miki, Antonia D. Boyer, John Ravits, Kelly A. Frazer, Vineet Bafna, Clark C. Chen, Paul S. Mischel, Gene W. Yeo, Frank B. Furnari
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The dearth of glioblastoma model systems that accurately recapitulate the disease remains a challenge. Here, the authors develop cancer avatars using genetically engineered human induced pluripotent cells.
Externí odkaz:
https://doaj.org/article/129339bec1d846d6beb84462802c2cb9