GUIDE: a randomised non-comparative phase II trial of biomarker-driven intermittent docetaxel versus standard-of-care docetaxel in metastatic castration-resistant prostate cancer (clinical trial protocol)

Autor: Conduit, C, Mak, B, Qu, W, Di Lulio, J, Burder, R, Bressel, M, Cusick, T, Dhillon, HM, De Abreu Lourenço, R, Underhill, C, Torres, J, Crumbaker, M, Honeyball, F, Linton, A, Allen, R, Davis, ID, Clark, SJ

Objective: To determine the efficacy and safety of intermittent docetaxel chemotherapy guided by circulating methylated glutathione S-transferase Pi-1 (mGSTP1) in men with metastatic castration-resistant prostate cancer (CRPC).Patients and Methods: G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::d88c0cba00da34503a7efd7783db2bf8
https://hdl.handle.net/10453/170426

Theology of the Parish, A: The Face of the Church in Challenging Times

Autor: William A. Clark, SJ, Austen Ivereigh

A Theology of the Parish answers skepticism about the pastoral role of theology by presenting a case for “Theology of the People” as an important tool for empowering whole communities at the local level of the Church.

ELF5 modulates the estrogen receptor cistrome in breast cancer

Autor: Piggin CL, Roden DL, Law AMK, Molloy MP, Krisp C, Swarbrick A, Naylor MJ, Kalyuga M, Kaplan W, Oakes SR, Gallego-Ortega D, Clark SJ, Carroll JS, Bartonicek N, Ormandy CJ

Acquired resistance to endocrine therapy is responsible for half of the therapeutic failures in the treatment of breast cancer. Recent findings have implicated increased expression of the ETS transcription factor ELF5 as a potential modulator of estr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::ef7b9c365267aa533a870a9ad19e6c61
https://hdl.handle.net/10453/144195

Using deterministic record linkage to link ambulance and emergency department data: is it possible without patient identifiers?

Autor: Clark, SJ, Halter, M, Porter, A, Smith, HC, Brand, M, Fothergill, R, Lindridge, SJ, McTigue, M, Snooks, H

Publikováno v: International Journal of Population Data Science, Vol 4, Iss 1 (2019)
International Journal of Population Data Science

Routine linkage of emergency ambulance records with those from the emergency department is uncommon in the UK. Our study, known as the Pre-Hospital Emergency Department Data Linking Project (PHED Data), aimed to link records of all patients conveyed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e5c40710f279302afbdd2c3f63f3e451
https://ijpds.org/article/view/1104

Why population-based data are crucial to achieving the Sustainable Development Goals

Autor: Sankoh, O, INDEPTH Network and partners, COLLABORATORS, Bangha, M, Emina, JB, Herbst, AJ, Tollman, S, Kant, S, Aaby, P, Chowdhury, A, Delaunay, V, Diallo, A, Khan, WA, Streatfield, K, Alam, N, Bhuiya, A, Ha, BT, Molla, M, Kebede, Y, Alberts, M, Toan, TK, Chuc, NT, Gyapong, M, Jasseh, M, Tessema, F, Nathan, R, Salim, A, Masanja, H, Punpuing, S, Crampin, A, Nyrienda, M, Kouanda, S, Mangen, FW, Lutalo, T, Sewankambo, N, Williams, TN, Scott, JA, Assefa, N, Adama, Y, Gebru, AA, Owusu-Agyei, S, Odhiambo, F, Otieno, W, Sifuna, P, Macete, E, Urassa, M, Larson, P, Ezeh, A, Beguy, D, Kyobutungi, C, Tinto, H, Oche, OM, Oduro, A, Sie, A, Soura, A, Wilopo, S, Sirima, S, Bonfoh, B, Juvekar, S, Sonko, B, Nguyen, BP, Meremikwu, M, Asiki, G, Thompson, R, Clark, SJ, Binka, F, Evans, T, Byass, P, Adami, HO, Campbell, H, Ekstrom, AM, Mwenesi, H, Ross, D, Mbacké, C, Moyer, C, Asangansi, I, Bocquier, P, Gage, J, McPake, B, Clark, J, Sturkenboom, M, Weibel, D, Bonhoeffer, J, Dolinger, D, Boehme, C, Ye, Y, de Savigny, D, Long, KZ, Käser, M, Karim, A, Mäusezahl, D, Tanner, M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::a48e44fd2eba5f6266c8a809b3db811f