Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Clarissa L. Durie"'
Autor:
Hayeon Lee, Yeseul Lee, Jinseok Lee, Hyeongseop Jeong, Dong Keon Yon, Clarissa L. Durie, Bumhan Ryu, Jeong Min Chung
Publikováno v:
Journal of Analytical Science and Technology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The selection of defocus ranges for small datasets in cryo-electron microscopy (cryo-EM) is under-researched. We present a comprehensive benchmark experiment that aimed to evaluate the relationship between contrast, defocus, and resolution,
Externí odkaz:
https://doaj.org/article/6bdbe9f1c3fe4669a5e6f379eaa933a1
Publikováno v:
Life, Vol 12, Iss 8, p 1267 (2022)
Cryo-electron microscopy (cryo-EM) has become an unrivaled tool for determining the structure of macromolecular complexes. The biological function of macromolecular complexes is inextricably tied to the flexibility of these complexes. Single particle
Externí odkaz:
https://doaj.org/article/43b80b65b6b74652aa7067a94720dc1b
Autor:
Elwood A. Mullins, Lauren E. Salay, Clarissa L. Durie, Jane E. Jackman, Melanie D. Ohi, Walter J. Chazin, Brandt F. Eichman
Publikováno v:
bioRxiv
The mechanism by which polymerase α–primase (polα–primase) synthesizes chimeric RNA-DNA primers of defined length and composition, necessary for replication fidelity and genome stability, is unknown. Here, we report cryo-EM structures of polα
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db20f3ea7498c2840f069236454f8cd1
https://europepmc.org/articles/PMC10055150/
https://europepmc.org/articles/PMC10055150/
Autor:
Jeong Min Chung, Louise Chang, Michael J Sheedlo, Melanie D. Ohi, Michele S. Swanson, Clarissa L Durie, Jacquelyn Roberts, D.B. Lacy
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Legionella pneumophila is an opportunistic pathogen that causes the potentially fatal pneumonia known as Legionnaires’ disease. The pathology associated with infection depends on bacterial delivery of effector proteins into the host via the membran
Autor:
Jeong Min Chung, Brenda G. Byrne, D. Borden Lacy, Michael J Sheedlo, Melanie D. Ohi, Thomas Knight, Min Su, Michele S. Swanson, Clarissa L Durie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c60382eded93900767a6548353a863c
https://doi.org/10.7554/elife.59530.sa2
https://doi.org/10.7554/elife.59530.sa2
Autor:
Jeong Min Chung, Michael J Sheedlo, Melanie D. Ohi, Timothy L. Cover, Neha Sawhney, D. Borden Lacy, Clarissa L Durie
Publikováno v:
eLife, Vol 9 (2020)
The pathogenesis of Helicobacter pylori-associated gastric cancer is dependent on delivery of CagA into host cells through a type IV secretion system (T4SS). The H. pylori Cag T4SS includes a large membrane-spanning core complex containing five prote
Autor:
Rachel E. Sutton, Rachel S. Nargi, Robert H. Carnahan, William B. Klimstra, Lauren E. Williamson, Elad Binshtein, Erica Armstrong, Theron Gilliland, Lauren M. Walker, Arthur S. Kim, James E. Crowe, Clarissa L Durie, Michael S. Diamond, Nurgun Kose, Pramod Kumar Yadav, Julie M. Fox, Melanie D. Ohi, Robin G. Bombardi
Publikováno v:
Cell
Eastern equine encephalitis virus (EEEV) is one of the most virulent viruses endemic to North America. No licensed vaccines or antiviral therapeutics are available to combat this infection, which has recently shown an increase in human cases. Here, w
Autor:
Michael J, Sheedlo, Jeong Min, Chung, Neha, Sawhney, Clarissa L, Durie, Timothy L, Cover, Melanie D, Ohi, D Borden, Lacy
Publikováno v:
eLife
The pathogenesis of Helicobacter pylori-associated gastric cancer is dependent on delivery of CagA into host cells through a type IV secretion system (T4SS). The H. pylori Cag T4SS includes a large membrane-spanning core complex containing five prote