Evaluating the prevalence and risk factors for macrolide resistance in Mycoplasma genitalium using a newly developed qPCR assay.

Autor: Joyce F Braam, David J Hetem, Clarissa E Vergunst, Sophie Kuizenga Wessel, Martijn S van Rooijen, Roel H T Nijhuis, Maarten F Schim van der Loeff, Alje P van Dam, Sylvia M Bruisten

Publikováno v: PLoS ONE, Vol 15, Iss 10, p e0240836 (2020)

Mycoplasma genitalium (MG) is a sexually transmitted bacterium in which macrolide resistance is rapidly increasing, limiting treatment options. We validated a new assay to detect the presence of macrolide resistance-associated mutations in MG (MG-MRA

Externí odkaz: https://doaj.org/article/8dcae11dc6c34827868a8d818a0816f7

High prevalence and resistance rates of Mycoplasma genitalium among patients visiting two sexually transmitted infection clinics in the Netherlands

Autor: Alje P. van Dam, David J. Hetem, Roel H. T. Nijhuis, Joyce F. Braam, Martijn S. van Rooijen, Jean-Marie Brand, Sophie Kuizenga Wessel, Clarissa E. Vergunst, Mary Berns, Sylvia M. Bruisten

Publikováno v: International journal of STD & AIDS, 32(9), 837-844. SAGE Publications Ltd
International Journal of STD and AIDS, 32(9), 837-844. SAGE Publications Ltd
Hetem, D J, Kuizenga Wessel, S, Bruisten, S M, Braam, J F, van Rooijen, M S, Vergunst, C E, Nijhuis, R H, Berns, M, Brand, J-M & van Dam, A P 2021, ' High prevalence and resistance rates of Mycoplasma genitalium among patients visiting two sexually transmitted infection clinics in the Netherlands ', International Journal of STD and AIDS, vol. 32, no. 9, pp. 837-844 . https://doi.org/10.1177/0956462421999287

Mycoplasma genitalium is a well-known cause of urethritis in men and has been associated with cervicitis, pelvic inflammatory disease, and adverse obstetric outcomes in women. In this cross-sectional study, we determined the current prevalence of M.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b4f9e4477e99b1f7f1be5a2b9f3fa9
https://doi.org/10.1177/0956462421999287

CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial

Autor: Arno W R, van Kuijk, Clarissa E, Vergunst, Danielle M, Gerlag, Barry, Bresnihan, Juan J, Gomez-Reino, Regine, Rouzier, Patrick C, Verschueren, Christiaan, van der Leij, Christiaan, van de Leij, Mario, Maas, Maarten C, Kraan, Paul P, Tak

Publikováno v: Annals of the rheumatic diseases, 69(11), 2013-2016. BMJ Publishing Group
Annals of the Rheumatic Diseases, 69(11), 2013-2016. BMJ Publishing Group

ObjectiveC-C chemokine receptor type 5 (CCR5), a chemokine receptor expressed on T cells and macrophages, and its ligands are found in inflamed synovial tissue (ST) of patients with rheumatoid arthritis (RA). The rationale for testing CCR5 blockade i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f659fb6371d2bdebd784751e24d679
https://doi.org/10.1136/ard.2010.131235

Chemokines: Their role in rheumatoid arthritis

Autor: Clarissa E. Vergunst, Paul P. Tak

Publikováno v: Current rheumatology reports, 7(5), 382-388. Current Science, Inc.

Chemokines are small proteins that can act on cells that express matching receptors. They are best known for their role in migration of cells, especially immune cells. Chemo-kine/ chemokine-receptor pairs are often functionally cate-gorized into thre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5187e54a80c156b2db8d89da9f2fbf68
https://doi.org/10.1007/s11926-005-0026-7

[A girl with desquamation of hands and feet]

Autor: Pui Khi, Chung, Clarissa E, Vergunst, Martijn, van der Kuip

Publikováno v: Nederlands tijdschrift voor geneeskunde. 158

A 3-year-old girl presented with desquamation of hands and feet, preceded by sore throat and subfebrile temperature. She developed exanthema with typical skip lesions and orange hyperkeratosis. The diagnosis 'classic juvenile pityriasis rubra pilaris

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b5421e58812ff40ea7097af0e6d7d119
https://pubmed.ncbi.nlm.nih.gov/24893811