Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Clarisa Vial"'
Publikováno v:
Proceedings of the National Academy of Sciences. 95:12977-12982
To determine the role of intracellular Ca 2+ in compaction, the first morphogenetic event in embryogenesis, we analyzed preimplantation mouse embryos under several decompacting conditions, including depletion of extracellular Ca 2+ , blocking of Ca 2
Publikováno v:
Cell Biochemistry and Function. 13:239-250
It has been demonstrated that microtubule-associated proteins (MAPs) interact with tubulin in vitro and in vivo. However, there is no clear evidence on the possible roles of the interactions of MAPs in vivo with other cytoskeletal components in maint
Publikováno v:
Journal of Cell Science. 105:51-60
The cytoskeletal integrity of human and rodent cell lines was analyzed using site-directed monoclonal antibodies prepared from hybridomas. Secreting hybridomas were produced by immunizing mice with synthetic peptides from the C-terminal domain of the
Publikováno v:
Cellular and Molecular Neurobiology. 13:173-182
1. Neurofibrillary tangles present in Alzheimer's disease and, in a lower proportion, in aged brains are formed mainly by paired helical filaments. The microtuble-associated protein tau is a major structural component of these filaments. In order to
Publikováno v:
Molecular and cellular biochemistry. 144(2)
Microtubule-associated proteins (MAPs) interact with tubulin in vitro and in vivo. Despite that there is a large amount of information on the roles of these proteins in neurons, the data on non-neuronal MAPs or MAPs-related proteins is scarce. There
Publikováno v:
Molecular and Cellular Biochemistry. 117
The antineoplastic drug estramustine is an adduct of estradiol and nor-nitrogen mustard. It has been shown that this drug interferes with microtubule assembly, an effect mediated by estramustine interaction with microtubule-associated proteins (MAPs)
Publikováno v:
Molecular and cellular biochemistry. 112(1)
The microtubule-associated protein Tau, a major component of brain microtubules, shares common repeated C-terminal sequences with the high molecular-weight protein MAP-2. It has been shown that tau peptides V187-G204 and V218-G235, representing two m