Zobrazeno 1 - 10 of 127 pro vyhledávání: '"Claridge TD"'
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α- and α'-lithiation-electrophile trapping of N-thiopivaloyl and N-tert-butoxythiocarbonyl α-substituted azetidines: rationalization of the regiodivergence using NMR and computation
Autor: Jackson, KE, Mortimer, CL, Odell, B, McKenna, JM, Claridge, TD, Paton, RS, Hodgson, DM
(1)H NMR and computational analyses provide insight into the regiodivergent (α- and α'-) lithiation-electrophile trapping of N-thiopivaloyl- and N-(tert-butoxythiocarbonyl)-α-alkylazetidines. The magnitudes of the rotation barriers in these azetid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::211e22742a8b5a4f4223d24702b9dae4
https://doi.org/10.1021/acs.joc.5b01804
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4
Akademický článek
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5
Akademický článek
mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.
Autor: Rydzik AM; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Zwirki i Wigury 93, 02-089 Warsaw, Poland.; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Warminski M; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Zwirki i Wigury 93, 02-089 Warsaw, Poland., Sikorski PJ; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland., Baranowski MR; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Zwirki i Wigury 93, 02-089 Warsaw, Poland., Walczak S; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.; College of Inter-Faculty Individual Studies in Mathematics and Natural Sciences, University of Warsaw, Zwirki i Wigury 93, 02-089 Warsaw, Poland., Kowalska J; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Zwirki i Wigury 93, 02-089 Warsaw, Poland., Zuberek J; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Zwirki i Wigury 93, 02-089 Warsaw, Poland., Lukaszewicz M; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Zwirki i Wigury 93, 02-089 Warsaw, Poland., Nowak E; Laboratory of Protein Structure, International Institute of Molecular and Cell Biology, 4 Ksiecia Trojdena Street, 02-109 Warsaw, Poland., W Claridge TD; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Darzynkiewicz E; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Zwirki i Wigury 93, 02-089 Warsaw, Poland.; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland., Nowotny M; Laboratory of Protein Structure, International Institute of Molecular and Cell Biology, 4 Ksiecia Trojdena Street, 02-109 Warsaw, Poland., Jemielity J; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.
Publikováno v: Nucleic acids research [Nucleic Acids Res] 2017 Sep 06; Vol. 45 (15), pp. 8661-8675.
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6
Akademický článek
19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.
Autor: Abboud MI; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Hinchliffe P; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Brem J; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Macsics R; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Pfeffer I; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Makena A; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Umland KD; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Rydzik AM; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Li GB; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Spencer J; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Claridge TD; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK., Schofield CJ; Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK.
Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2017 Mar 27; Vol. 56 (14), pp. 3862-3866. Date of Electronic Publication: 2017 Mar 02.
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7
Akademický článek
Protein-ligand binding affinity determination by the waterLOGSY method: An optimised approach considering ligand rebinding.
Autor: Huang R; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Victoria Street West, Auckland 1142, New Zealand., Bonnichon A; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom.; Université D'Auvergne, 49 Boulevard François-Mitterrand, CS 60032, Clermont Ferrand 63001, Cedex 1, France., Claridge TD; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom., Leung IK; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Victoria Street West, Auckland 1142, New Zealand.
Publikováno v: Scientific reports [Sci Rep] 2017 Mar 03; Vol. 7, pp. 43727. Date of Electronic Publication: 2017 Mar 03.
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8
Akademický článek
Aromatic and antiaromatic ring currents in a molecular nanoring.
Autor: Peeks MD; University of Oxford, Department of Chemistry, Chemistry Research Laboratory, Oxford OX1 3TA, UK., Claridge TD; University of Oxford, Department of Chemistry, Chemistry Research Laboratory, Oxford OX1 3TA, UK., Anderson HL; University of Oxford, Department of Chemistry, Chemistry Research Laboratory, Oxford OX1 3TA, UK.
Publikováno v: Nature [Nature] 2017 Jan 12; Vol. 541 (7636), pp. 200-203. Date of Electronic Publication: 2016 Dec 19.
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9
Akademický článek
Torsional and Electronic Factors Control the C-H⋅⋅⋅O Interaction.
Autor: Driver RW; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Claridge TD; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Scheiner S; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah, 84322-0300, USA. steve.scheiner@usu.edu., Smith MD; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK. martin.smith@chem.ox.ac.uk.
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2016 Nov 07; Vol. 22 (46), pp. 16513-16521. Date of Electronic Publication: 2016 Oct 06.
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10
Akademický článek
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity.
Autor: Wright TH; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Bower BJ; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Chalker JM; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Bernardes GJ; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Wiewiora R; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Ng WL; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Raj R; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Faulkner S; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Vallée MR; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Phanumartwiwath A; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Coleman OD; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Thézénas ML; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Headington, Oxford OX3 7FZ, UK., Khan M; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Galan SR; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Lercher L; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Schombs MW; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Gerstberger S; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Palm-Espling ME; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Baldwin AJ; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Headington, Oxford OX3 7FZ, UK., Claridge TD; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Mohammed S; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Davis BG; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK. ben.davis@chem.ox.ac.uk.
Publikováno v: Science (New York, N.Y.) [Science] 2016 Nov 04; Vol. 354 (6312). Date of Electronic Publication: 2016 Sep 22.
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