Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Claridge, TDW"'
Publikováno v:
Journal of the American Chemical Society. 144:14790-14797
There are few enantioconvergent reactions in which racemic substrates bearing multiple stereochemical features are converted into products with high levels of diastereo- and enantiocontrol. Here, we disclose a process for the highly enantio- and dias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465445ad9fcf56b16be67969f09ffb8a
https://doi.org/10.1021/jacs.2c05485
https://doi.org/10.1021/jacs.2c05485
Autor:
Buchanan, Cj, Gaunt, B, Harrison, Pj, Yang, Y, Liu, J, Khan, A, Giltrap, Am, Le Bas, A, Ward, Pn, Gupta, K, Dumoux, M, Tan, Tk, Schimaski, L, Daga, S, Picchiotti, N, Baldassarri, M, Benetti, E, Fallerini, C, Fava, F, Giliberti, A, Koukos, Pi, Davy, Mj, Lakshminarayanan, A, Xue, X, Papadakis, G, Deimel, Lp, Casablancas-Antràs, V, Claridge, Tdw, Bonvin, Amjj, Settentau, Qj, Furini, S, Gori, M, Huo, J, Owens, Rj, Schaffitzel, C, Berger, I, Renieri, A, GEN-COVID Multicenter Study, Naismith, Jh, Baldwin, Aj, Davis, Bg
Publikováno v:
Science, 377(6604), 1. American Association for the Advancement of Science
Berger-Schaffitzel, C H & Berger, I 2022, ' Pathogen-sugar interactions revealed by universal saturation transfer analysis ', Science, vol. 377, no. 6604 . https://doi.org/10.1126/science.abm3125
Science
Berger-Schaffitzel, C H & Berger, I 2022, ' Pathogen-sugar interactions revealed by universal saturation transfer analysis ', Science, vol. 377, no. 6604 . https://doi.org/10.1126/science.abm3125
Science
Many pathogens exploit host cell-surface glycans. However, precise analyses of glycan ligands binding with heavily modified pathogen proteins can be confounded by overlapping sugar signals and/or compounded with known experimental constraints. Univer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f495263d9986e4c507c6361f37e4830a
https://ora.ox.ac.uk/objects/uuid:983bb274-46bb-4873-8119-d49f6684e908
https://ora.ox.ac.uk/objects/uuid:983bb274-46bb-4873-8119-d49f6684e908
Autor:
Tianrong Yeo, Jacqueline Palace, Patrick Waters, M Sealey, Daniel C. Anthony, Claridge Tdw., Ana Cavey, Maria Isabel Leite, Mark Woodhall, Fay Probert, Maciej Juryńczyk
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
ObjectiveTo determine whether unsupervised principal component analysis (PCA) of comprehensive clinico-radiologic data can identify phenotypic subgroups within antibody-negative patients with overlapping features of multiple sclerosis (MS) and neurom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1bfbc2de5885e3cc6b85168e2dee4a
https://ora.ox.ac.uk/objects/uuid:8969ab17-f14e-499b-bf16-50bd7c9efff4
https://ora.ox.ac.uk/objects/uuid:8969ab17-f14e-499b-bf16-50bd7c9efff4
Autor:
GOWAR, Mrs ZAHN, Rydzik, AM, Brem, J, Chandler, SA, Benesch, JLP, Claridge, TDW, Schofield, CJ
19F NMR protein observed spectroscopy is evaluated as a method for analysing protein metal binding using the New Delhi metallo-β-lactamase 1. The results imply 19F NMR is useful for analysis of different metallated protein states and investigations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738aa20ec8b5683344301e6652378c67
https://doi.org/10.1039/c9md00416e
https://doi.org/10.1039/c9md00416e
The final step in the biosynthesis of L-carnitine in humans is catalysed by the 2-oxoglutarate and ferrous iron dependent oxygenase, γ-butyrobetaine hydroxylase (BBOX). 1H and 19F NMR studies inform on the BBOX mechanism including by providing evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::02041e62dba1900c5e7ec9f7846d1440
https://ora.ox.ac.uk/objects/uuid:f28b1f12-0af1-4fd5-ab25-8e5f40b585bd
https://ora.ox.ac.uk/objects/uuid:f28b1f12-0af1-4fd5-ab25-8e5f40b585bd
Lead(IV) reagents are widely used for the mediation of oxidation and carbon-carbon bond-forming reactions, which are postulated to proceed by mechanisms involving ligand exchange processes at the metal centre. This paper reports multinuclear (207Pb,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2cc4611b21d499e907f012824e0fd0e8
https://doi.org/10.1002/(sici)1097-458x(199703)35:3<159::aid-omr51>3.3.co
https://doi.org/10.1002/(sici)1097-458x(199703)35:3<159::aid-omr51>3.3.co
207Pb NMR spectroscopy was used to investigate 20 lead(IV) tetracarboxylates both in solution and in the solid state by cross-polarization magic angle spinning (CP/MAS) NMR. There is generally good correlation between isotropic chemical shifts in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4b63de74a877bb06629904890ffc08db
https://ora.ox.ac.uk/objects/uuid:a562dfbb-8f90-4f43-a7d4-71b88b975a56
https://ora.ox.ac.uk/objects/uuid:a562dfbb-8f90-4f43-a7d4-71b88b975a56
Anomalous cross-peaks observed in the NOESY spectra of 2,4-disubstituted thiazolidines and oxazolidines that cannot be attributed to classical dipolar NOE or chemical exchange peaks have been investigated experimentally and computationally and have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::edd3982333b04f205791ced1a5371690
https://doi.org/10.1021/acs.joc.6b00458
https://doi.org/10.1021/acs.joc.6b00458
Whole cells of the bacterium Rhodococcus rhodochrous LL100-21, which had been grown on benzonitrile to induce the nitrilase enzyme, converted benzonitrile to benzohydroxamic acid in the presence of hydroxylamine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::60e8a6621b6fd849051c31e3bf4a56f2
https://doi.org/10.1023/a:1005657206039
https://doi.org/10.1023/a:1005657206039