Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Claridge, TDW"'
Publikováno v:
Journal of the American Chemical Society. 144:14790-14797
There are few enantioconvergent reactions in which racemic substrates bearing multiple stereochemical features are converted into products with high levels of diastereo- and enantiocontrol. Here, we disclose a process for the highly enantio- and dias
Autor:
Buchanan, Cj, Gaunt, B, Harrison, Pj, Yang, Y, Liu, J, Khan, A, Giltrap, Am, Le Bas, A, Ward, Pn, Gupta, K, Dumoux, M, Tan, Tk, Schimaski, L, Daga, S, Picchiotti, N, Baldassarri, M, Benetti, E, Fallerini, C, Fava, F, Giliberti, A, Koukos, Pi, Davy, Mj, Lakshminarayanan, A, Xue, X, Papadakis, G, Deimel, Lp, Casablancas-Antràs, V, Claridge, Tdw, Bonvin, Amjj, Settentau, Qj, Furini, S, Gori, M, Huo, J, Owens, Rj, Schaffitzel, C, Berger, I, Renieri, A, GEN-COVID Multicenter Study, Naismith, Jh, Baldwin, Aj, Davis, Bg
Publikováno v:
Science, 377(6604), 1. American Association for the Advancement of Science
Berger-Schaffitzel, C H & Berger, I 2022, ' Pathogen-sugar interactions revealed by universal saturation transfer analysis ', Science, vol. 377, no. 6604 . https://doi.org/10.1126/science.abm3125
Science
Berger-Schaffitzel, C H & Berger, I 2022, ' Pathogen-sugar interactions revealed by universal saturation transfer analysis ', Science, vol. 377, no. 6604 . https://doi.org/10.1126/science.abm3125
Science
Many pathogens exploit host cell-surface glycans. However, precise analyses of glycan ligands binding with heavily modified pathogen proteins can be confounded by overlapping sugar signals and/or compounded with known experimental constraints. Univer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f495263d9986e4c507c6361f37e4830a
https://ora.ox.ac.uk/objects/uuid:983bb274-46bb-4873-8119-d49f6684e908
https://ora.ox.ac.uk/objects/uuid:983bb274-46bb-4873-8119-d49f6684e908
Autor:
Tianrong Yeo, Jacqueline Palace, Patrick Waters, M Sealey, Daniel C. Anthony, Claridge Tdw., Ana Cavey, Maria Isabel Leite, Mark Woodhall, Fay Probert, Maciej Juryńczyk
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
ObjectiveTo determine whether unsupervised principal component analysis (PCA) of comprehensive clinico-radiologic data can identify phenotypic subgroups within antibody-negative patients with overlapping features of multiple sclerosis (MS) and neurom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1bfbc2de5885e3cc6b85168e2dee4a
https://ora.ox.ac.uk/objects/uuid:8969ab17-f14e-499b-bf16-50bd7c9efff4
https://ora.ox.ac.uk/objects/uuid:8969ab17-f14e-499b-bf16-50bd7c9efff4
Autor:
GOWAR, Mrs ZAHN, Rydzik, AM, Brem, J, Chandler, SA, Benesch, JLP, Claridge, TDW, Schofield, CJ
19F NMR protein observed spectroscopy is evaluated as a method for analysing protein metal binding using the New Delhi metallo-β-lactamase 1. The results imply 19F NMR is useful for analysis of different metallated protein states and investigations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738aa20ec8b5683344301e6652378c67
https://doi.org/10.1039/c9md00416e
https://doi.org/10.1039/c9md00416e
Autor:
Tianrong Yeo, T Winkler, Maciej Juryńczyk, Daniel C. Anthony, Ana Cavey, Eric Schiffer, Nicola R. Sibson, George Tackley, Jacqueline Palace, Gabriele C. DeLuca, Fay Probert, Siddharth Arora, Angela Vincent, Patrick Waters, Claridge Tdw., M. Isabel Leite, Mark Woodhall
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-13 (2017)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
The overlapping clinical features of relapsing remitting multiple sclerosis (RRMS), aquaporin-4 (AQP4)-antibody (Ab) neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein (MOG)-Ab disease mean that detection of disea
The final step in the biosynthesis of L-carnitine in humans is catalysed by the 2-oxoglutarate and ferrous iron dependent oxygenase, γ-butyrobetaine hydroxylase (BBOX). 1H and 19F NMR studies inform on the BBOX mechanism including by providing evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::02041e62dba1900c5e7ec9f7846d1440
https://ora.ox.ac.uk/objects/uuid:f28b1f12-0af1-4fd5-ab25-8e5f40b585bd
https://ora.ox.ac.uk/objects/uuid:f28b1f12-0af1-4fd5-ab25-8e5f40b585bd
Lead(IV) reagents are widely used for the mediation of oxidation and carbon-carbon bond-forming reactions, which are postulated to proceed by mechanisms involving ligand exchange processes at the metal centre. This paper reports multinuclear (207Pb,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2cc4611b21d499e907f012824e0fd0e8
https://doi.org/10.1002/(sici)1097-458x(199703)35:3<159::aid-omr51>3.3.co
https://doi.org/10.1002/(sici)1097-458x(199703)35:3<159::aid-omr51>3.3.co
207Pb NMR spectroscopy was used to investigate 20 lead(IV) tetracarboxylates both in solution and in the solid state by cross-polarization magic angle spinning (CP/MAS) NMR. There is generally good correlation between isotropic chemical shifts in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4b63de74a877bb06629904890ffc08db
https://ora.ox.ac.uk/objects/uuid:a562dfbb-8f90-4f43-a7d4-71b88b975a56
https://ora.ox.ac.uk/objects/uuid:a562dfbb-8f90-4f43-a7d4-71b88b975a56
Anomalous cross-peaks observed in the NOESY spectra of 2,4-disubstituted thiazolidines and oxazolidines that cannot be attributed to classical dipolar NOE or chemical exchange peaks have been investigated experimentally and computationally and have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::edd3982333b04f205791ced1a5371690
https://doi.org/10.1021/acs.joc.6b00458
https://doi.org/10.1021/acs.joc.6b00458