Zobrazeno 1 - 10
of 1 585
pro vyhledávání: '"Clarence T"'
Autor:
Kelvin C. C. Pong, Yuen Sze Lai, Roy Chi Hang Wong, Alan Chun Kit Lee, Sam C. T. Chow, Jonathan C. W. Lam, Ho Pui Ho, Clarence T. T. Wong
Publikováno v:
Biosensors, Vol 14, Iss 8, p 392 (2024)
Three-dimensional (3D) spheroid models are crucial for cancer research, offering more accurate insights into tumour biology and drug responses than traditional 2D cell cultures. However, inconsistent and low-throughput spheroid production has hindere
Externí odkaz:
https://doaj.org/article/902979ed7fed4597805d5097657042e2
Autor:
Bo Tang, Kwai Man Lau, Yunxin Zhu, Chihao Shao, Wai-Ting Wong, Larry M. C. Chow, Clarence T. T. Wong
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 71 (2024)
Delivering bioactive proteins into cells without carriers presents significant challenges in biomedical applications due to limited cell membrane permeability and the need for targeted delivery. Here, we introduce a novel carrier-free method that add
Externí odkaz:
https://doaj.org/article/0caeb3b8fb77445485d4ff5e60824df5
Publikováno v:
Cancer Medicine, Vol 8, Iss 9, Pp 4417-4427 (2019)
Abstract Biliary reflux has been considered a potential risk factor in upper aerodigestive tract malignancies. It is not yet clearly known how pH affects the bile‐induced activation of NF‐κB and its related oncogenic pathway previously linked to
Externí odkaz:
https://doaj.org/article/92a8fcfdf8d64a338fe4f7f6bf36a978
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 4, Pp 374-386 (2018)
PURPOSE: Bile-containing gastroesophageal reflux may promote cancer at extraesophageal sites. Acidic bile can accelerate NF-κB activation and molecular events, linked to premalignant changes in murine hypopharyngeal mucosa (HM). We hypothesize that
Externí odkaz:
https://doaj.org/article/1c03e2b5f55d467ca61c12614772837f
Autor:
Clarence T. Sasaki, Dimitra P. Vageli
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 6, Pp 329-338 (2016)
Gastroduodenal refluxate found in the upper aerodigestive tract is not clinically uncommon. We recently demonstrated the neoplastic potential of gastroduodenal fluids (GDF) on hypopharyngeal mucosa, via NF-κB, using in vitro and in vivo models. Here
Externí odkaz:
https://doaj.org/article/8d53c487d41d4ec8954d5749caf2b279
Autor:
Sotirios G. Doukas, Dimitra P. Vageli, George Lazopoulos, Demetrios A. Spandidos, Clarence T. Sasaki, Aristidis Tsatsakis
Publikováno v:
Cells, Vol 9, Iss 4, p 1031 (2020)
Tobacco smoking is a common risk factor for lung cancer and head and neck cancer. Molecular changes such as deregulation of miRNA expression have been linked to tobacco smoking in both types of cancer. Dysfunction of the Mismatch DNA repair (MMR) mec
Externí odkaz:
https://doaj.org/article/4c0d48666f38467590705e97d8b3e1ef
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168269 (2016)
Extra-esophageal carcinogenesis has been widely discussed in relation to the chronic effects of laryngopharyngeal reflux and most prominently with pepsin historically central to this discussion. With refluxate known to include gastric (pepsin) and du
Externí odkaz:
https://doaj.org/article/08a13978a8db404dba4e02b0bb6fccd6
Autor:
Clarence T. K. Chu
Publikováno v:
Journal of Library and Information Studies, Vol 3, Iss 1/2, Pp 1-13 (2005)
Media literacy is an area of study of great concern to scholars and educators in mass education. The term refers to one's ability to decode and use messages carried through all forms of media (especially visual medium such as photograph, picture, mov
Externí odkaz:
https://doaj.org/article/b40aa28a37274baebd52ecce6582ebc2