Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Clarence K Mah"'
Autor:
Clarence K. Mah, Noorsher Ahmed, Nicole A. Lopez, Dylan C. Lam, Avery Pong, Alexander Monell, Colin Kern, Yuanyuan Han, Gino Prasad, Anthony J. Cesnik, Emma Lundberg, Quan Zhu, Hannah Carter, Gene W. Yeo
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-25 (2024)
Abstract The spatial organization of molecules in a cell is essential for their functions. While current methods focus on discerning tissue architecture, cell–cell interactions, and spatial expression patterns, they are limited to the multicellular
Externí odkaz:
https://doaj.org/article/370b90adee9c46aa93c11ebcecb1cb61
Autor:
Clarence K. Mah, Alexander T. Wenzel, Edwin F. Juarez, Thorin Tabor, Michael M. Reich, Jill P. Mesirov
Publikováno v:
F1000Research, Vol 7 (2019)
Single-cell RNA sequencing (scRNA-seq) has emerged as a popular method to profile gene expression at the resolution of individual cells. While there have been methods and software specifically developed to analyze scRNA-seq data, they are most access
Externí odkaz:
https://doaj.org/article/84c5a4cadaec4b25875d585a8538e4fb
Publikováno v:
F1000Research, Vol 7 (2018)
Illumina Infinium DNA methylation arrays are a cost-effective technology to measure DNA methylation at CpG sites genome-wide and across cohorts of normal and cancer samples. While copy number alterations are commonly inferred from array-CGH, SNP arra
Externí odkaz:
https://doaj.org/article/661dc12ad1574abd9b3481a1a2eba89f
Autor:
Clarence K. Mah, Noorsher Ahmed, Nicole Lopez, Dylan Lam, Alexander Monell, Colin Kern, Yuanyuan Han, Gino Prasad, Anthony J. Cesnik, Emma Lundberg, Quan Zhu, Hannah Carter, Gene W. Yeo
The spatial organization of molecules in a cell is essential for performing their functions. Spatial transcriptomics technologies have opened the door to characterization of cellular and subcellular organization. While current computational methods f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11916e4ff912792a87dac0a6518b33ca
https://doi.org/10.1101/2022.06.10.495510
https://doi.org/10.1101/2022.06.10.495510
Autor:
Scott DeGrand, Robert M Gallant, Xaver Audhya, Victoria Nudell, Ryan J. Marina, Kristian G. Andersen, Evelyn S Crescini, Peter De Hoff, Tom Barber, Laura Nicholson, Gene W. Yeo, Sheldon Gilmer, Tyler Buckley, Toan T Ngo, Lauge Farnaes, Pedro Belda-Ferre, Chandana Tekkatte, Kyle McBride, Justin Ryan, Catelyn Anderson, Audra R Meadows, J Joelle Donofrio-Odmann, Louise C. Laurent, Clarence K Mah, Kari Lee, Nathaniel L. Matteson, Michelle McGraw, Daniel McDonald, Brian A. Yee, Andrew C. Richardson, Lizbeth Franco Vargas, Abbas Hakim, Shawn I. Walsh, Natasha K. Martin, Lakshmi E. Batachari, Phoebe Seaver, Kathleen M Sweeney, Jasmine R. Mueller, Mehrbod Estaki, Min Yi Wu, Bryan McDonald, Michele Freddock, Rebecca Tsai, L.M. Sewall, Samuel S Park, Matthew Kim, Nicole G. Coufal, Holly Valentine, Charlotte A. Hobbs, Emily Eisner, Julie Nguyen, Elijah S. Lawrence, Viet Ha Nguyen, Michal Machnicki, Nadja Ilkenhans, Brent Brainard, LaVonnye Chong, Marni Jacobs, Robert Logan, Jason Z. Zhang, Shashank Sathe, Amber L Morey, Sunil M. Kurian, David Dimmock, Alhakam Nouri, Anelizze Castro-Martínez, Denise Malacki, Christopher A Ruiz, August Williams, Lisa Sacco, Jamie Case, Noorsher Ahmed, Clarisse Marotz, Daniel Maunder, Isaraphorn Pratumchai, Greg Humphrey, Alma L Lastrella, Michelle Meyer, Michelle Franc Ragsac, Valentina Lo Sardo, Christopher L. Marsh, Eugenio Nunez, Edyta M Grzelak, R Tyler Ostrander, Qishan Liang, Bing Xia, Nina J Gao, Rob Knight, Bhavika K Kapadia, Jonathan Hart, Nathan A Baer, Celestine Magallanes, Bethany Barrick, Elizabeth W Smoot, Priyadarshini Pantham, David Picone, Stefan Aigner, Marisol Chacón, Michael M. Quigley, Sharada Saraf, Willi Cheung, Hanna Liliom, Refugio Robles-Sikisaka, Maryann Betty, Christopher A. Kahn, Andrea Galmozzi, Mark Zeller, Ashley Plascencia, Kyle O'Neill, Sydney C. Morgan, Steven M. Blue
BackgroundSuccessful containment strategies for SARS-CoV-2, the causative virus of the COVID-19 pandemic, have involved widespread population testing that identifies infections early and enables rapid contact tracing. In this study, we developed a ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0897b86a960260b818a43692ebbd6837
https://doi.org/10.1101/2021.06.25.21257885
https://doi.org/10.1101/2021.06.25.21257885
Autor:
Sydney C. Morgan, Stefan Aigner, Catelyn Anderson, Pedro Belda-Ferre, Peter De Hoff, Clarisse Marotz, Shashank Sathe, Mark Zeller, Noorsher Ahmed, Xaver Audhya, Nathan A. Baer, Tom Barber, Bethany Barrick, Lakshmi Batachari, Maryann Betty, Steven M. Blue, Brent Brainard, Tyler Buckley, Jamie Case, Anelizze Castro-Martinez, Marisol Chacón, Willi Cheung, LaVonnye Chong, Nicole G. Coufal, Evelyn S. Crescini, Scott DeGrand, David P. Dimmock, J. Joelle Donofrio-Odmann, Emily R. Eisner, Mehrbod Estaki, Lizbeth Franco Vargas, Michelle Freddock, Robert M. Gallant, Andrea Galmozzi, Nina J. Gao, Sheldon Gilmer, Edyta M. Grzelak, Abbas Hakim, Jonathan Hart, Charlotte Hobbs, Gregory Humphrey, Nadja Ilkenhans, Marni Jacobs, Christopher A. Kahn, Bhavika K. Kapadia, Matthew Kim, Sunil Kurian, Alma L. Lastrella, Elijah S. Lawrence, Kari Lee, Qishan Liang, Hanna Liliom, Valentina Lo Sardo, Robert Logan, Michal Machnicki, Celestine G. Magallanes, Clarence K. Mah, Denise Malacki, Ryan J. Marina, Christopher Marsh, Natasha K. Martin, Nathaniel L. Matteson, Daniel J. Maunder, Kyle McBride, Bryan McDonald, Michelle McGraw, Audra R. Meadows, Michelle Meyer, Amber L. Morey, Jasmine R. Mueller, Toan T. Ngo, Viet Nguyen, Laura J. Nicholson, Alhakam Nouri, Victoria Nudell, Eugenio Nunez, Kyle O'Neill, R. Tyler Ostrander, Priyadarshini Pantham, Samuel S. Park, David Picone, Ashley Plascencia, Isaraphorn Pratumchai, Michael Quigley, Michelle Franc Ragsac, Andrew C. Richardson, Refugio Robles-Sikisaka, Christopher A. Ruiz, Justin Ryan, Lisa Sacco, Sharada Saraf, Phoebe Seaver, Leigh Sewall, Elizabeth W. Smoot, Kathleen M. Sweeney, Chandana Tekkatte, Rebecca Tsai, Holly Valentine, Shawn Walsh, August Williams, Min Yi Wu, Bing Xia, Brian Yee, Jason Z. Zhang, Kristian G. Andersen, Lauge Farnaes, Rob Knight, Gene W. Yeo, Louise C. Laurent
Publikováno v:
SSRN Electronic Journal.
Autor:
Xiuxing Wang, Wenchao Zhou, Lukas Chavez, Shideng Bao, Andrew E Sloan, Michael A. Vogelbaum, Jean A. Bernatchez, Kelsey C. Bertrand, Peter C. Scacheri, Q Wu, Irtisha Singh, Clarence K. Mah, Stephen C. Mack, Jair L. Siqueira-Neto, Zhixin Qiu, Andrew R. Morton, Rosie Villagomez, Sisi Lai, Gene H. Barnett, Christine Lee, Rachel A. Hirsch, Briana C. Prager, Jeremy N. Rich, Zhe Zhu, Ryan C. Gimple, Charles Y. Lin, Leo J.Y. Kim
Publikováno v:
The Journal of Experimental Medicine
Mack et al. defined active chromatin landscapes of glioblastoma stem cells (GSCs) and primary tumor specimens, revealing novel transcriptional regulatory circuits and therapeutic targets. Super-enhancers identified essential transcription factors tha
Autor:
Clarence K. Mah, Miriam Adam, Owen Chapman, Jill P. Mesirov, Lukas Chavez, Tenley C. Archer, Filip Mundt, Tobias Ehrenberger, Jesse R. Dixon, Scot L. Pomeroy, Maxwell P. Gold, Sahaana Chandran, Ernest Fraenkel, Karsten Krug
Publikováno v:
Cancer Research. 80:447-447
Medulloblastoma (MB) is one of the most common pediatric brain tumors. Current treatment options carry substantial risk for lifelong cognitive and neurological impairment. Consequently, there is a pressing need to elucidate molecular mechanisms with
Autor:
Ernest Fraenkel, Jill P. Mesirov, Andrey Korshunov, Pablo Tamayo, James Jensen, Scott L. Pomeroy, Michael A. Gillette, Hailei Zhang, Marcel Kool, Colin J. Daniel, Divya Ramamoorthy, Lauren C. Tang, Jessica Pierre-Francois, Michael S. Noble, Alexander LeNail, Jonathan O. Lipton, D. R. Mani, Maxwell P. Gold, Rosalie C. Sears, Tobias Ehrenberger, Tenley C. Archer, Elizabeth L. Mahoney, Karsten Krug, Clarence K. Mah, Philipp Mertins, Filip Mundt, Paul A. Northcott, Jacob Silterra, Karl R. Clauser, Steven A. Carr, Stefan M. Pfister
Publikováno v:
Cancer cell, vol 34, iss 3
PMC
PMC
There is a pressing need to identify therapeutic targets in tumors with low mutation rates such as the malignant pediatric brain tumor medulloblastoma. To address this challenge, we quantitatively profiled global proteomes and phospho-proteomes of 45
Autor:
Alexander T. Wenzel, Thorin Tabor, Clarence K. Mah, Edwin F. Juarez, Michael Reich, Jill P. Mesirov
Publikováno v:
F1000Research
Single-cell RNA sequencing (scRNA-seq) has emerged as a popular method to profile gene expression at the resolution of individual cells. While there have been methods and software specifically developed to analyze scRNA-seq data, they are most access