Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Clarence B. Vaughn"'
Autor:
Jacob D. Bitran, Clarence B. Vaughn, Gary S. Lazar, Gabriel N. Hortobagyi, Aman U. Buzdar, Silvana Martino, Gary Spitzer, Charles E. Vogel, Robert W. Dubois, Stephen E. Jones, Sandra M. Swain, Robert Peter Gale, Rolla Edward Park
Publikováno v:
Clinical Transplantation. 14:32-41
BACKGROUND There is controversy whether high-dose chemotherapy and a blood cell or bone marrow autotransplant is a better treatment than conventional-dose chemotherapy for women with local/regional or metastatic breast cancer. Subject selection and t
Autor:
Saul E. Rivkin, C. Kent Osborne, John J. Costanzi, J. W. Athens, Danika Lew, Clarence B. Vaughn, Stephanie J. Green, Silvana Martino
Publikováno v:
Cancer. 97(1)
BACKGROUND Adjuvant combination chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil plus vincristine and prednisone (CMFVP) was compared with single-agent L-phenylalanine mustard (L-PAM) for the treatment of patients with axillary ly
Publikováno v:
Investigational new drugs. 8(1)
Esorubicin (4' deoxydoxorubicin) is a new analogue of the anthracycline, doxorubicin. This compound lacks the hydroxyl group at 4' position on the amino sugar of the anthracycline. Phase II study was designed to determine the clinical response rate a
Autor:
Clarence B. Vaughn, Edward J. Treisman, Barry R. Herschman, Gayle Groshko, Janet Chapman, Pauline L. Nirenberg, Michael J. Bonczak
Publikováno v:
Medical and pediatric oncology. 18(1)
Five to ten percent of patients with adenocarcinoma of the endometrium present with advanced disease [1] or develop metastasis and require systemic therapy for control of disease. About one-third (33%) of recurrent or advanced endometrial cancer resp
Autor:
Ben Lin Hom, Robert Chapman, Joel G. Lucas, Harry E. Hynes, John Crowley, Clarence B. Vaughn, Robert B. Livingston
Publikováno v:
Investigational New Drugs. 11:91-92
This trial employing MGBG, vinblastine, and cisplatin in patients with advanced NSCLC produced a 10% response rate with no durable responses. This is disappointing compared to previously cited studies, although the median overall survival of 7.0 mont
Autor:
Ronald L. Stephens, Stanley P. Balcerzak, Jess Frank, Robert M. O'Bryan, Clarence B. Vaughn, Howard S. Levin, J. J. Costanzi, Montague Lane, Charles A. Coltman
Publikováno v:
Cancer. 53:406-410
Over a 24-month period, the Southwest Oncology Group (SWOG) conducted a randomized prospective chemotherapeutic trial in 158 patients with advanced prostatic cancer. Patients were initially randomized to receive either a combination of Adriamycin and
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 43:387-393
The patterns of radioactive estrogen metabolites in the plasma of patients with a variety of malignancies were determined after the injection of physiological amounts of 17β-estradiol-6,7-3H or of estrone-6,7-3H. The metabolites were separated and i
Autor:
Thomas R. Maloney, Mary A. Foulkes, William S. Fletcher, Barth Hoogstraten, J. J. Costanzi, Nazli Gad-el-Mawla, Clarence B. Vaughn, Bill L. Tranum, J. W. Athens
Publikováno v:
Cancer. 54:2248-2256
The Southwest Oncology Group has completed a study of 213 women with the first recurrence of breast cancer. Eligibility included a radical or modified radical mastectomy for cure and recurrence which had received no other form of therapy. Patients we
Autor:
J. Benjamin Green, Stephanie Green, P. N. Grozea, Robert M. O'Bryan, Clarence B. Vaughn, Noboru Oishi, William S. Fletcher, Melvin L. Reed, Barbara Metch
Publikováno v:
Medical and Pediatric Oncology. 16:312-319
One hundred twenty-two patients with advanced adenocarcinoma of the breast were randomized to receive adriamycin (AD) alone or a combination of VP-16 plus lower dose adriamycin (VAD). The patients were stratified to good and poor risk. The starting d
Autor:
Clarence B. Vaughn, Vainutis K. Vaitkevicius, Laurence H. Baker, Melvin L. Reed, Muhyi Al-Sarraf
Publikováno v:
Cancer. 33:513-518
Combination chemotherapy has been used in the treatment of acute leukemia, malignant lymphoma, and, more recently, solid tumors. This study was designed to randomize between combination 5-fluorouracil (5-FU) cyclophosphamide, and vincristine sulfate,