Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Clare Vesely"'
Autor:
Nadia Hégarat, Clare Vesely, P K Vinod, Cory Ocasio, Nisha Peter, Julian Gannon, Antony W Oliver, Béla Novák, Helfrid Hochegger
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004004 (2014)
Entry into mitosis is triggered by activation of Cdk1 and inactivation of its counteracting phosphatase PP2A/B55. Greatwall kinase inactivates PP2A/B55 via its substrates Ensa and ARPP19. Both Greatwall and Ensa/ARPP19 are regulated by phosphorylatio
Externí odkaz:
https://doaj.org/article/a8ec7b573e9743e3938c8cb598895b1e
Autor:
Tim Meyer, Teresa Marafioti, Sergio A. Quezada, Karl Peggs, Christos Toumpanakis, Martyn Caplin, Chrissie Thirlwell, Tu Vinh Luong, Amir Gander, Olagunju Ogunbiyi, Javier Herrero, Lucia Conde, Heli Vaikkinen, Pawan Dhami, Ayse U. Akarca, Alexa Childs, Yien Ning Sophia Wong, Clare Vesely
Supplementary Data from Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b21416a7dce2193bc61d72e5612fc0c
https://doi.org/10.1158/1078-0432.22486557
https://doi.org/10.1158/1078-0432.22486557
Autor:
Tim Meyer, Teresa Marafioti, Sergio A. Quezada, Karl Peggs, Christos Toumpanakis, Martyn Caplin, Chrissie Thirlwell, Tu Vinh Luong, Amir Gander, Olagunju Ogunbiyi, Javier Herrero, Lucia Conde, Heli Vaikkinen, Pawan Dhami, Ayse U. Akarca, Alexa Childs, Yien Ning Sophia Wong, Clare Vesely
Purpose:The immune tumor microenvironment and the potential therapeutic opportunities for immunotherapy in small intestinal neuroendocrine tumors (siNET) have not been fully defined.Experimental Design:Herein, we studied 40 patients with primary and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e62c014a2e3243652c68f6bcf35aad
https://doi.org/10.1158/1078-0432.c.6532341
https://doi.org/10.1158/1078-0432.c.6532341
Autor:
Tim Meyer, Teresa Marafioti, Sergio A. Quezada, Karl Peggs, Christos Toumpanakis, Martyn Caplin, Chrissie Thirlwell, Tu Vinh Luong, Amir Gander, Olagunju Ogunbiyi, Javier Herrero, Lucia Conde, Heli Vaikkinen, Pawan Dhami, Ayse U. Akarca, Alexa Childs, Yien Ning Sophia Wong, Clare Vesely
Supplementary Table from Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33adef37e53562846258689ff6c5ee01
https://doi.org/10.1158/1078-0432.22486527
https://doi.org/10.1158/1078-0432.22486527
Autor:
Lucia Conde, Leah Ensell, Javier Herrero, Martyn Caplin, John A. Hartley, Christos Toumpanakis, Clare Vesely, Nischalan Pillay, Alexa Childs, Christopher D. Steele, Francesca M Rizzo, Pawan Dhami, Christina Thirlwell, Helen Lowe, Tim Meyer, Heli Vaikkinen, Tu Vinh Luong
Publikováno v:
Endocrine-Related Cancer
Single-cell profiling of circulating tumor cells (CTCs) as part of a minimally invasive liquid biopsy presents an opportunity to characterize and monitor tumor heterogeneity and evolution in individual patients. In this study, we aimed to compare sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c47baef0fb1caf6635e4cb3e8600fe
http://europepmc.org/articles/PMC8428071
http://europepmc.org/articles/PMC8428071
Autor:
Clare Vesely, Yien Ning Sophia Wong, Alexa Childs, Ayse U. Akarca, Pawan Dhami, Heli Vaikkinen, Lucia Conde, Javier Herrero, Olagunju Ogunbiyi, Amir Gander, Tu Vinh Luong, Chrissie Thirlwell, Martyn Caplin, Christos Toumpanakis, Karl Peggs, Sergio A. Quezada, Teresa Marafioti, Tim Meyer
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 28(12)
Purpose: The immune tumor microenvironment and the potential therapeutic opportunities for immunotherapy in small intestinal neuroendocrine tumors (siNET) have not been fully defined. Experimental Design: Herein, we studied 40 patients with primary a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1830786a8b25d863ebc3781ef6d95e3
https://pubmed.ncbi.nlm.nih.gov/35320356
https://pubmed.ncbi.nlm.nih.gov/35320356
Autor:
Martyn Caplin, Tim Meyer, Alexa Childs, Christos Toumpanakis, Tu Vinh Luong, Christina Thirlwell, John A. Hartley, Leah Ensell, Helen Lowe, Clare Vesely
Publikováno v:
British Journal of Cancer
Background: Neuroendocrine tumours (NET) overexpress somatostatin receptors (SSTR) that can be targeted for therapy. Somatostatin receptor expression is routinely measured by molecular imaging but the resolution is insufficient to define heterogeneit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c06ad414b6ad5b9fc1765a38ac8636
https://doi.org/10.1038/bjc.2016.377
https://doi.org/10.1038/bjc.2016.377
Autor:
Dalvinder Mandair, Helen Lowe, John A. Hartley, Martyn Caplin, Clare Vesely, Leah Ensell, Victoria J. Spanswick, Tim Meyer
Publikováno v:
Endocrine-Related Cancer. 23:L29-L32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::730556ddbbcb9d186d041d768aa3a78f
https://doi.org/10.1530/erc-16-0201
https://doi.org/10.1530/erc-16-0201
Autor:
Patrick J. McIntyre, Richard Bayliss, Kevan M. Shokat, Krister J. Barkovich, Alexander A. Warkentin, Clare Vesely, Cory A. Ocasio, John Spencer
Publikováno v:
ACS chemical biology. 13(10)
Analogue-sensitive (AS) kinases contain large to small mutations in the gatekeeper position rendering them susceptible to inhibition with bulky analogues of pyrazolopyrimidine-based Src kinase inhibitors (e.g., PP1). This “bump-hole” method has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83aeb1285dbb2f4a07a5f847a9d30047
https://pubmed.ncbi.nlm.nih.gov/30239186
https://pubmed.ncbi.nlm.nih.gov/30239186
Autor:
Martyn Caplin, Francesca M Rizzo, Alexa Childs, Daniel Krell, Ayse U. Akarca, Dalvinder Mandair, Mauro Cives, Helen Lowe, Franco Silvestris, Teresa Marafioti, John A. Hartley, Tu Vinh Luong, Tim Meyer, Clare Vesely, Leah Ensell, Mohid S. Khan, Christos Toumpanakis, Christina Thirlwell
Publikováno v:
British Journal of Cancer
Background Bone metastases are associated with a worse outcome in patients with neuroendocrine tumours (NETs). Tumour overexpression of C-X-C chemokine receptor 4 (CXCR4) appears predictive of skeletal involvement. We investigated the role of circula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85eb12c0067f1b928c95a79836e00763
https://pubmed.ncbi.nlm.nih.gov/30636773
https://pubmed.ncbi.nlm.nih.gov/30636773