Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Clare Stretton"'
Autor:
Ken Mackie, Jonathan S. Hundal, Simon Hastings, H. S. Hundal, Christopher Lipina, Andrew J. Irving, Clare Stretton
Publikováno v:
Diabetes
The endogenous cannabinoid (or endocannabinoid) system (ECS) is part of a central neuromodulatory system thought to play a key role in the regulation of feeding behavior and energy balance. However, increasing evidence suggests that modulation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabdee46be0e4ad434621945351afc6d
http://europepmc.org/articles/PMC8385612
http://europepmc.org/articles/PMC8385612
Publikováno v:
Diabetes [Diabetes] 2021 Aug; Vol. 70 (8), pp. 1910. Date of Electronic Publication: 2021 Jul 08.
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 3, Pp 838-858 (2020)
Abstract Background Caveolin‐3 (Cav3) is the principal structural component of caveolae in skeletal muscle. Dominant pathogenic mutations in the Cav3 gene, such as the Limb Girdle Muscular Dystrophy‐1C (LGMD1C) P104L mutation, result in substanti
Externí odkaz:
https://doaj.org/article/333c56061fcd4028b3ac40c2fb14ab18
Publikováno v:
Redox Biology, Vol 35, Iss , Pp 101484- (2020)
Hydrogen peroxide appears to be the key reactive oxygen species involved in redox signalling, but comparisons of the low concentrations of hydrogen peroxide that are calculated to exist within cells with those previously shown to activate common sign
Externí odkaz:
https://doaj.org/article/70def8b334e8497a89b61c2b658ddbff
Autor:
Thorsten M. Hoffmann, Emma Cwiklinski, Dinesh S. Shah, Clare Stretton, Russell Hyde, Peter M. Taylor, Harinder S. Hundal
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The SNAT2 (SLC38A2) System A amino acid transporter mediates Na+-coupled cellular uptake of small neutral α-amino acids (AAs) and is extensively regulated in response to humoral and nutritional cues. Understanding the basis of such regulation is imp
Externí odkaz:
https://doaj.org/article/e1b74f02ec334fc1989cc58cf9f21f5a
Autor:
Katherine Macrae, Clare Stretton, Christopher Lipina, Agnieszka Blachnio-Zabielska, Marcin Baranowski, Jan Gorski, Anna Marley, Harinder S. Hundal
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 9, Pp 2366-2378 (2013)
Chronic exposure of skeletal muscle to saturated fatty acids, such as palmitate (C16:0), enhances proinflammatory IKK-NFκB signaling by a mechanism involving the MAP kinase (Raf-MEK-ERK) pathway. Raf activation can be induced by its dissociation fro
Externí odkaz:
https://doaj.org/article/9e61b45a61e84b389bc5eee7a75ee2ca
Autor:
Clare Stretton, Anne McArdle, Graeme L. Close, Brian McDonagh, Malcolm J. Jackson, Jamie N. Pugh
Publikováno v:
Free Radical Biology & Medicine
Skeletal muscle generates superoxide during contractions which is rapidly converted to H2O2. This molecule has been proposed to activate signalling pathways and transcription factors that regulate key adaptive responses to exercise but the concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170cb48a4492f9170169dbcd6411f122
https://doi.org/10.1016/j.freeradbiomed.2020.06.020
https://doi.org/10.1016/j.freeradbiomed.2020.06.020
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 3, Pp 838-858 (2020)
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle
Background Caveolin‐3 (Cav3) is the principal structural component of caveolae in skeletal muscle. Dominant pathogenic mutations in the Cav3 gene, such as the Limb Girdle Muscular Dystrophy‐1C (LGMD1C) P104L mutation, result in substantial loss o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354c3f780aba13194eabe78c2d661bc8
https://doaj.org/article/333c56061fcd4028b3ac40c2fb14ab18
https://doaj.org/article/333c56061fcd4028b3ac40c2fb14ab18
Publikováno v:
Free Radical Biology and Medicine. 192:18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e727e426e074abaa0a5e85802996387
https://doi.org/10.1016/j.freeradbiomed.2022.10.012
https://doi.org/10.1016/j.freeradbiomed.2022.10.012
Autor:
Anne McArdle, Graeme L. Close, Philip Brownridge, Clare Stretton, Brian McDonagh, Malcolm J. Jackson, Jamie N. Pugh
Publikováno v:
Free radical biologymedicine. 177
Reactive oxygen species (ROS) are recognized as important signaling molecules in healthy skeletal muscle. Redox sensitive proteins can respond to intracellular changes in ROS by oxidation of reactive thiol groups on cysteine (Cys) residues. Exercise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c270ce81aeabde065123a909cacf5ec6
https://pubmed.ncbi.nlm.nih.gov/34655746
https://pubmed.ncbi.nlm.nih.gov/34655746