Výsledky vyhledávání - "Clare M. Williams"

Akademický článek

Allergic Airway Disease Prevents Lethal Synergy of Influenza A Virus-Streptococcus pneumoniae Coinfection

Autor: Sean Roberts, Sharon L. Salmon, Donald J. Steiner, Clare M. Williams, Dennis W. Metzger, Yoichi Furuya

Publikováno v: mBio, Vol 10, Iss 4 (2019)

ABSTRACT Fatal outcomes following influenza infection are often associated with secondary bacterial infections. Allergic airway disease (AAD) is known to influence severe complications from respiratory infections, and yet the mechanistic effect of AA

Externí odkaz: https://doaj.org/article/9dd5786ecf724d57874c90af930d89a7

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Akademický článek

Impact of Pre-Existing Immunity to Influenza on Live-Attenuated Influenza Vaccine (LAIV) Immunogenicity

Autor: Sreeja Roy, Clare M. Williams, Danushka K. Wijesundara, Yoichi Furuya

Publikováno v: Vaccines, Vol 8, Iss 4, p 683 (2020)

During the previous influenza seasons, between 2010 and 2016, the live attenuated influenza vaccine (LAIV) provided variable efficacy against influenza in the U.S., causing the recommendation against the use of the LAIV. In striking contrast, pre-cli

Externí odkaz: https://doaj.org/article/f60d06e423bb4ec8beba21c5c81737ad

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Akademický článek

Evaluation of Pneumococcal Surface Protein A as a Vaccine Antigen against Secondary Streptococcus pneumoniae Challenge during Influenza A Infection

Autor: Sean Roberts, Clare M. Williams, Sharon L. Salmon, Jesse L. Bonin, Dennis W. Metzger, Yoichi Furuya

Publikováno v: Vaccines, Vol 7, Iss 4, p 146 (2019)

Secondary bacterial pneumonia is responsible for significant morbidity and mortality during seasonal and pandemic influenza. Due to the unpredictability of influenza A virus evolution and the time-consuming process of manufacturing strain-specific in

Externí odkaz: https://doaj.org/article/cc68d25350c148e0acb6948fa6b059b1

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Akademický článek

LUNG group 2 innate lymphoid cells as a new adjuvant target to enhance intranasal vaccine efficacy against influenza

Autor: Clare M Williams, Sreeja Roy, Wei Sun, Andrea M Furuya, Danushka K Wijesundara, Yoichi Furuya

Publikováno v: Clinical & Translational Immunology, Vol 11, Iss 3, Pp n/a-n/a (2022)

Abstract Group 2 innate lymphoid cells (ILC2) are a relatively new class of innate immune cells. Lung ILC2 are early responders that secrete type 2 cytokines in response to danger ‘alarmin’ signals such as interleukin (IL)‐33 and thymic stromal

Externí odkaz: https://doaj.org/article/d2996f0cafee4670aa3b8594262405bc

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Fear of Influenza Resurgence amid COVID-19 Pandemic: Need for Effective Flu Vaccine Still Exists

Autor: Danushka K. Wijesundara, Wei Sun, Clare M Williams, Andrea K. M. Furuya, Yoichi Furuya

Publikováno v: Vaccines, Vol 9, Iss 1198, p 1198 (2021)
Vaccines

As influenza season was approaching in 2020, public health officials feared that influenza would worsen the COVID-19 situation [...]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a840344a8f5c802f0605ead89cdfa10
https://www.mdpi.com/2076-393X/9/10/1198

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The Interleukin-33-Group 2 Innate Lymphoid Cell Axis Represents a Potential Adjuvant Target To Increase the Cross-Protective Efficacy of Influenza Vaccine

Autor: Sreeja Roy, Andrew N. J. McKenzie, Clare M Williams, Yoichi Furuya, Danielle Califano, Dennis W. Metzger

Publikováno v: J Virol

Interleukin-33 (IL-33) is a multifunctional cytokine that mediates type 2-dominated immune responses. In contrast, the role of IL-33 during viral vaccination, which often aims to induce type 1 immunity, has not been fully investigated. Here, we exami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee587cc6432e356ce95e2263d71de45c
https://pubmed.ncbi.nlm.nih.gov/34468174

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Detrimental impact of allergic airway disease on live attenuated influenza vaccine

Autor: Yoichi Furuya, Clare M Williams, Sreeja Roy

Publikováno v: Health Science Reports, Vol 4, Iss 3, Pp n/a-n/a (2021)
Health Science Reports

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078c314e4f82be4de94f54aa75ca54b9
https://doaj.org/article/ba3f5840dbed4f09a225a9e984b91072

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Impact of pre-existing immunity on live attenuated influenza vaccine-induced cross-protective immunity

Autor: Clare M Williams, Danushka K. Wijesundara, Yoichi Furuya, Julián Pardo, Sreeja Roy

Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Vaccines
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza

The efficacy of the intranasally (i.n.) delivered live attenuated influenza vaccine (LAIV) is variable and, in some seasons, suboptimal. In this study, we report that LAIV exhibits cross-protective efficacy in mice, potentially associated with cellul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97296ba7c50a0335dc99dedbe77ae088
http://zaguan.unizar.es/record/95801

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A Triple-challenge Mouse Model of Allergic Airway Disease, Primary Influenza Infection, and Secondary Bacterial Infection

Autor: Clare M Williams, Sreeja Roy, Yoichi Furuya, Sean Roberts

Publikováno v: Bio Protoc

Asthma is a global problem that affects millions of individuals. An increased risk of respiratory viral and bacterial infections is one of the complications of asthma. We recently reported that mice with ovalbumin-induced allergic airway disease (AAD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493f2716fc529cf54709f28f2655fdbf
https://doi.org/10.21769/bioprotoc.3583

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