Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Clare M. Waterman-Storer"'
Autor:
Ssang-Taek Lim, Dusko Ilic, Hong Lin, Margaret L. Gardel, Xiao Lei Chen, Rafaela Cañete-Soler, Sean Uryu, Perihan Nalbant, Alok Tomar, Yangmi Lim, Joie A. Bernard-Trifilo, William W. Schlaepfer, David D. Schlaepfer, Gary M. Bokoch, Jinbin Zhai, Clare M. Waterman-Storer
Publikováno v:
The Journal of Cell Biology
Integrin binding to matrix proteins such as fibronectin (FN) leads to formation of focal adhesion (FA) cellular contact sites that regulate migration. RhoA GTPases facilitate FA formation, yet FA-associated RhoA-specific guanine nucleotide exchange f
Publikováno v:
Journal of Cell Science. 120:3475-3487
Cell migration requires spatial and temporal regulation of filamentous actin (F-actin) dynamics. This regulation is achieved by distinct actin-associated proteins, which mediate polymerization, depolymerization, severing, contraction, bundling or eng
Autor:
Nazilla B. Alderson, Johan de Rooij, Asier Echarri, Araceli Grande-García, Clare M. Waterman-Storer, Miguel A. del Pozo, Jose M. Valdivielso
Publikováno v:
The Journal of Cell Biology
Development, angiogenesis, wound healing, and metastasis all involve the movement of cells in response to changes in the extracellular environment. To determine whether caveolin-1 plays a role in cell migration, we have used fibroblasts from knockout
Publikováno v:
Annual Review of Biophysics and Biomolecular Structure. 35:361-387
Fluorescent speckle microscopy (FSM) is a technology used to analyze the dynamics of macromolecular assemblies in vivo and in vitro. Speckle formation by random association of fluorophores with a macromolecular structure was originally discovered for
Autor:
Johan de Rooij, Andre Kerstens, Clare M. Waterman-Storer, Martin A. Schwartz, Gaudenz Danuser
Publikováno v:
The Journal of Cell Biology
The scattering of Madin-Darby canine kidney cells in vitro mimics key aspects of epithelial–mesenchymal transitions during development, carcinoma cell invasion, and metastasis. Scattering is induced by hepatocyte growth factor (HGF) and is thought
Autor:
Stephanie L. Gupton, Clare M. Waterman-Storer, Aaron Ponti, Sarah E. Hitchcock-DeGregori, Karen L. Anderson, Gaudenz Danuser, Denis Wirtz, Thomas P. Kole, Dorit Hanein, Velia M. Fowler, Robert S. Fischer
Publikováno v:
The Journal of Cell Biology
The actin cytoskeleton is locally regulated for functional specializations for cell motility. Using quantitative fluorescent speckle microscopy (qFSM) of migrating epithelial cells, we previously defined two distinct F-actin networks based on their F
Publikováno v:
The Journal of Cell Biology
Proteins that in cells specifically bind to growing microtubule plus ends (+TIPs) are thought to play important roles in polarization of the cytoskeleton. However, most +TIPs do not show a bias of their microtubule-binding behavior toward different s
Publikováno v:
Journal of Biological Chemistry. 279:6196-6203
In the leading edge of migrating cells, a subset of microtubules exhibits net growth in a Rac1- and p21-activated kinase-dependent manner. Here, we explore the possibility of whether phosphorylation and inactivation of the microtubule-destabilizing p
Publikováno v:
Journal of Microscopy. 211:191-207
Summary Fluorescent speckle microscopy (FSM) is a technology for analysing the dynamics of macromolecular assemblies. Originally, the effect of random speckle formation was discovered with microtubules. Since then, the method has been expanded to oth
Publikováno v:
Scopus-Elsevier
Fluorescent speckle microscopy (FSM) is a new imaging technique with the potential for simultaneous visualization of translocation and dynamic turnover of polymer structures. However, the use of FSM has been limited by the lack of specialized softwar