Výsledky vyhledávání - "Clare M. Brown"

Harry Pasley Higginson and his role in the re-discovery of the dodo (Raphus cucullatus)

Autor: Clare M. Brown

Publikováno v: Archives of Natural History. 47:381-391

Harry Pasley Higginson, a railway engineer from Yorkshire, northeast England, is one of the people credited with the first discovery of mid-Holocene dodo ( Raphus cucullatus) bones at Mare aux Songes, Mauritius, in 1865. A question still hangs over w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::233ef69362b8f5589df3379aef86c52a
https://doi.org/10.3366/anh.2020.0662

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Influenza Classification from Short Reads with VAPOR Facilitates Robust Mapping Pipelines and Zoonotic Strain Detection for Routine Surveillance Applications

Autor: Thomas R. Connor, Benjamin Southgate, S. Corden, Catherine Moore, Joel Southgate, Matthew J. Bull, Joanne Watkins, Clare M. Brown

Publikováno v: Bioinformatics

BackgroundInfluenza viruses are associated with a significant global public health burden. The segmented RNA genome of influenza changes continually due to mutation, and the accumulation of these changes within the antigenic recognition sites of haem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd890cdd354f3f424c25b378e3c35a3d
https://doi.org/10.1101/597062

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Escalating Regulation of 5T4-Specific IFN-γ+ CD4+ T Cells Distinguishes Colorectal Cancer Patients from Healthy Controls and Provides a Target for In Vivo Therapy

Autor: Simon Phillips, Awen Gallimore, Martin J. Scurr, Tom Pembroke, Kathryn Smart, M. M. Davies, Andrew James Godkin, Clare M. Brown, Rohit Srinivasan, Tom Hockey, Hayley Bridgeman, Rachel Hargest, Adam Christian, Anja Bloom

Publikováno v: Cancer Immunology Research. 1:416-425

The relationship between the adaptive CD4+ T-cell response and human cancer is unclear. The oncofetal antigen 5T4 is expressed in many human carcinomas, including colorectal cancer cells, but has limited expression on normal tissues. We previously id

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d26e0dcc374ceaaca7e6fa2614e89ef9
https://doi.org/10.1158/2326-6066.cir-13-0035

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Assessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer

Autor: Martin J, Scurr, Clare M, Brown, Diana F, Costa Bento, Gareth J, Betts, Brian I, Rees, Robert K, Hills, Awen, Gallimore, Andrew, Godkin

Publikováno v: JNCI Journal of the National Cancer Institute

Current dogma suggests that tumor-reactive IFN-γ–producing (TH1-type) T-cells are beneficial to patient outcome; however, the clinical consequence of these responses with respect to long-term prognosis in colorectal cancer (CRC) is not understood.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c3b2131530cf69eacad37f1dc0a9df9
https://pubmed.ncbi.nlm.nih.gov/25669203

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PWE-151 Cell-Mediated Immune Recognition of Cea Is Associated with Early Tumour Recurrence Following Resection of Colorectal Cancer

Autor: Andrew James Godkin, Martin J. Scurr, Awen Gallimore, Clare M. Brown, G Betts

Publikováno v: Gut. 62:A192.2-A193

Introduction Colorectal cancer (CRC) is one of the commonest malignancies in men and women. Clinical staging is used to predict prognosis after resection. The interaction of the cancer with the adaptive cellular immune response plays an important rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::83330c95a3a4621aed43482f6db935a2
https://doi.org/10.1136/gutjnl-2013-304907.439

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