Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Clare M Reynolds"'
Autor:
Samuel S Haysom, Mark H Vickers, Lennex H Yu, Clare M Reynolds, Elwyn C Firth, Sue R McGlashan
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188411 (2017)
To determine if a high-fat diet (HF) from weaning would result in a pro-inflammatory state and affect joint cartilage, we fed male rats either HF or Chow diet post-weaning, and voluntary wheel exercise (EX) or cage only activity (SED) after 9 weeks o
Externí odkaz:
https://doaj.org/article/1b051da985724393bf3d77d250defa1f
Autor:
Chantal Anne Pileggi, Christopher Paul Hedges, Stephanie Anne Segovia, James Frederick Markworth, Brenan R Durainayagam, Clint Gray, Xiaoyuan D Zhang, Matthew Philip Greig Barnett, Mark H Vickers, Anthony John Hickey, Clare M Reynolds, David Cameron-Smith
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
A maternal high-fat (HF) diet during pregnancy can lead to metabolic compromise such as insulin resistance in adult offspring. Skeletal muscle mitochondrial dysfunction is one mechanism contributing to metabolic impairments in insulin resistant state
Externí odkaz:
https://doaj.org/article/5c4bd2c3d1ea48f298ac6952748e6b4e
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3342 (2018)
Gestational diabetes mellitus (GDM) is a serious pregnancy complication, in which women without previously diagnosed diabetes develop chronic hyperglycemia during gestation. In most cases, this hyperglycemia is the result of impaired glucose toleranc
Externí odkaz:
https://doaj.org/article/0e93f49f469f467db8e11f09d58edaad
Autor:
Michelle L. Kearns, Clare M. Reynolds
Publikováno v:
Experimental Physiology, Vol 109, Iss 5, Pp 633-646 (2024)
Abstract Pregnancy represents a period of immense maternal physiological adaptation, with progressive increases in lipid storage potential and insulin resistance to support fetal/placental growth. This requires significant change in the adipose tissu
Externí odkaz:
https://doaj.org/article/0fe0a306afad4fbc99827f43607c25e9
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115994 (2015)
Maternal high fat intake during pregnancy and lactation can result in obesity and adverse cardio-metabolic status in offspring independent of postnatal diet. While it is clear that maternal high fat intake can cause hypertension in adult offspring, t
Externí odkaz:
https://doaj.org/article/b3bc1ed7b66b49af9380376f639207a6
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139567 (2015)
Externí odkaz:
https://doaj.org/article/aefa1312abdf455f8f3bd1b8000a80da
Autor:
Orla M Finucane, Clare M Reynolds, Fiona C McGillicuddy, Karen A Harford, Martine Morrison, John Baugh, Helen M Roche
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113369 (2014)
Macrophage infiltration is a critical determinant of high-fat diet induced adipose tissue inflammation and insulin resistance. The precise mechanisms underpinning the initiation of macrophage recruitment and activation are unclear. Macrophage migrati
Externí odkaz:
https://doaj.org/article/abe0fe83c03848e1903cd220bad85b8a
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68262 (2013)
Maternal undernutrition (UN) is associated with the development of obesity and metabolic complications in adult offspring. While the role of inflammation in obesity and related comorbidities has been well established, there is little evidence regardi
Externí odkaz:
https://doaj.org/article/7c5010092225404f901c2d96d17fb8cd
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53505 (2013)
Maternal undernutrition results in elevated blood pressure (BP) and endothelial dysfunction in adult offspring. However, few studies have investigated interventions during early life to ameliorate the programming of hypertension and vascular disorder
Externí odkaz:
https://doaj.org/article/04cc89960adb4db68fdda15963f92d3d
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76961 (2013)
Maternal obesity is associated with obesity and metabolic disorders in offspring. However, intervention strategies to reverse or ameliorate the effects of maternal obesity on offspring health are limited. Following maternal undernutrition, taurine su
Externí odkaz:
https://doaj.org/article/3f439c42c3324ec29519511e5bd8a177