Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Clare Lefave"'
Autor:
Ted Laderas, Pierrette Lo, Shannon K. McWeeney, Yoko Kosaka, Guang Fan, Clare Lefave, Adam J. Lamble, Cristina E. Tognon, Lauren K. Brady, Marc M. Loriaux, Allie Maffit, Jennifer N. Saultz, Andy Kaempf, David Soong, Motomi Mori, Weiwei Wang, Homer Adams, Nicola Long, Fei Huang, Brian J. Druker, Evan F. Lind, Jeffrey W. Tyner
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with a 5-y survival of 29%. Immunotherapy is based on the premise that tumors suppress the immune system. We investigated the status of T cell immunity in AML at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15339f906426a6b4a5b79931d6d9a59b
http://europepmc.org/articles/PMC7321988
http://europepmc.org/articles/PMC7321988
Autor:
Magdalena Zajac, Jessica K.R. Boult, Lauren C.J. Baker, Astrid Koehler, Tapan K. Nayak, Anton Belousov, Jean Tessier, Clare Lefave, Fabian Birzele, Markus Thomas, Simon P. Robinson, Carsten Horn, Chia Huey Ooi
Publikováno v:
British Journal of Cancer
Background: To assess antivascular effects, and evaluate clinically translatable magnetic resonance imaging (MRI) biomarkers of tumour response in vivo, following treatment with vanucizumab, a bispecific human antibody against angiopoietin-2 (Ang-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41dd09a929399866723a9bd7092a47d0
https://pubmed.ncbi.nlm.nih.gov/27529514
https://pubmed.ncbi.nlm.nih.gov/27529514
Autor:
Michael Schaffer, Ted Laderas, Brian J. Druker, Pegah Safabakhsh, Fei Huang, Shannon K. McWeeney, Yoko Kosaka, Homer Adams, Clare Lefave, Lauren K. Brady, Adam J. Lamble, David Soong, Evan F. Lind, Brendan P. Hodkinson, Yann Abraham, Jeffrey W. Tyner
Publikováno v:
Blood. 132:2750-2750
Advances in Acute Myeloid Leukemia (AML) research have shown that the bone marrow microenvironment may distinctly vary across disease subtypes, and that this variation is associated with disease risk and response to conventional therapies. Novel ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a19c0ff8653e0fe7be4c00d6ecabc724
https://doi.org/10.1182/blood-2018-99-118424
https://doi.org/10.1182/blood-2018-99-118424
Publikováno v:
BMC Medical Genomics
Background Epigenome-wide studies in hepatocellular carcinoma (HCC) have identified numerous genes with aberrant DNA methylation. However, methods for triaging functional candidate genes as useful biomarkers for epidemiological study have not yet bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7511bc74833ebcba53fff8acf3eedffa
https://doi.org/10.1186/s12920-015-0105-1
https://doi.org/10.1186/s12920-015-0105-1
Autor:
Rocio del A. Cordona, Manju Basu, Juan Jiang, Michael J. Pugia, Joshua Henshaw, Sara Seggerson, Patrick J. Boyle, Subhash Basu, Clare Lefave, A.E. Miller
Publikováno v:
Glycoconjugate Journal. 21:487-496
Infectious disease, commonly caused by bacterial pathogens, is now the world's leading cause of premature death and third overall cause behind cardiovascular disease and cancer. Urinary Tract Infection (UTI), caused by E. coli bacteria, is a very com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ef69d6a730a6071a670f23acf2ec0b
https://doi.org/10.1007/s10719-004-5539-1
https://doi.org/10.1007/s10719-004-5539-1
Publikováno v:
Journal of Bioequivalence & Bioavailability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3041f4c4cc9ea64d47a608b5626c85c6
https://doi.org/10.4172/0975-0851.1000004
https://doi.org/10.4172/0975-0851.1000004
Autor:
Andrew C. Lysaght, Henk M. Lokhorst, A. Kate Sasser, Brendan M. Weiss, Tahamtan Ahmadi, Tineke Casneuf, Niels W.C.J. van de Donk, Clare Lefave, Jaime Bald
Publikováno v:
Blood. 126:1837-1837
Introduction: Daratumumab (DARA) is a human IgG1κ monoclonal antibody that binds with high affinity to a unique epitope on CD38. DARA monotherapy has shown promising activity in relapsed and/or refractory multiple myeloma (MM) patients with a median
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::897211ca05ba086a8665eeb564d59441
https://doi.org/10.1182/blood.v126.23.1837.1837
https://doi.org/10.1182/blood.v126.23.1837.1837
Autor:
Michael R. McDevitt, Christophe Antczak, David A. Scheinberg, Jaspreet Singh Jaggi, Clare Lefave, Michael Curcio
Current limitations to applications of monoclonal antibody (mAb) targeted isotope generators in radioimmunotherapy include the low mAb labeling yields and the non-specific radiation of normal tissues by non-targeted radioimmunoconjugates (RIC). Radio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11aba2ee8b97e5bcff47db000a9ea558
https://europepmc.org/articles/PMC2570787/
https://europepmc.org/articles/PMC2570787/
Publikováno v:
The Journal of chemical physics. 121(3)
We have investigated the orientation ordering of two shish-kebab chains confined by spherically harmonic potentials through Monte Carlo simulations and asymptotic analysis. The rigid rod is modeled as shish-kebab chains consisting of tangent hard sph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbf73162395baae2568cce177352a8e
https://pubmed.ncbi.nlm.nih.gov/15260706
https://pubmed.ncbi.nlm.nih.gov/15260706
Publikováno v:
Gastroenterology. 146:S-311
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8515af7caa0be5143e8d770a9db47b82
https://doi.org/10.1016/s0016-5085(14)61115-x
https://doi.org/10.1016/s0016-5085(14)61115-x