Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Clare L. Curl"'
Autor:
David J. Anderson, David I. Kaplan, Katrina M. Bell, Katerina Koutsis, John M. Haynes, Richard J. Mills, Dean G. Phelan, Elizabeth L. Qian, Ana Rita Leitoguinho, Deevina Arasaratnam, Tanya Labonne, Elizabeth S. Ng, Richard P. Davis, Simona Casini, Robert Passier, James E. Hudson, Enzo R. Porrello, Mauro W. Costa, Arash Rafii, Clare L. Curl, Lea M. Delbridge, Richard P. Harvey, Alicia Oshlack, Michael M. Cheung, Christine L. Mummery, Stephen Petrou, Andrew G. Elefanty, Edouard G. Stanley, David A. Elliott
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
A gene regulatory network, including the transcription factor Nkx2-5, regulates cardiac development. Here, the authors show that on deletion of NKX2-5 from human embryonic stem cells, there is impaired cardiomyogenesis and changes in action potential
Externí odkaz:
https://doaj.org/article/0896462d0f5d479da41ae7191f638c59
Autor:
Mauro W. Costa, Richard J. Mills, Elizabeth Ng, Christine L. Mummery, Ana Rita Leitoguinho, Enzo R. Porrello, Deevina Arasaratnam, John M. Haynes, Edouard G. Stanley, Michael Cheung, Tanya Labonne, Robert Passier, Simona Casini, Richard P. Harvey, David A. Elliott, Alicia Oshlack, Katerina Koutsis, James E. Hudson, Katrina M. Bell, Clare L. Curl, Arash Rafii, David A. Anderson, D Phelan, Lea M.D. Delbridge, Richard P. Davis, Elizabeth L. Qian, Stephen Petrou, David I. Kaplan, Andrew G. Elefanty
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature communications, 9(1):1373. Nature Publishing Group
Nature Communications
Nature communications, 9(1):1373. Nature Publishing Group
Congenital heart defects can be caused by mutations in genes that guide cardiac lineage formation. Here, we show deletion of NKX2-5, a critical component of the cardiac gene regulatory network, in human embryonic stem cells (hESCs), results in impair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeda87e0b9195a49bdab8b7359a067e
https://doi.org/10.1038/s41467-018-03714-x
https://doi.org/10.1038/s41467-018-03714-x