Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Clare J Rowntree"'
Results from UKALL60+, a phase 2 study in older patients with untreated acute lymphoblastic leukemia
Autor:
Bela Patel, Amy A. Kirkwood, Clare J. Rowntree, Krisztina Z. Alapi, Emilio Barretta, Laura Clifton‐Hadley, Tom Creasey, SooWah Lee, David I. Marks, Anthony V. Moorman, Nicholas Morley, Pip Patrick, Zaynab Rana, Anita Rijneveld, John A. Snowden, Adele K. Fielding
Publikováno v:
HemaSphere, Vol 8, Iss 6, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/f8ed0d4f316040aaadab89e48c475ad0
Autor:
Thomas Creasey, Emilio Barretta, Sarra L. Ryan, Ellie Butler, Amy A. Kirkwood, Daniel Leongamornlert, Elli Papaemmanuil, Pip Patrick, Laura Clifton-Hadley, Bela Patel, Tobias Menne, Andrew K. McMillan, Christine J. Harrison, Clare J. Rowntree, Nick Morley, David I. Marks, Adele K. Fielding, Anthony V. Moorman
Publikováno v:
Haematologica, Vol 107, Iss 9 (2021)
Despite being predominantly a childhood disease, the incidence of acute lymphoblastic leukemia (ALL) has a second peak in adults aged 60 years and over. These older adults fare extremely poorly with existing treatment strategies and very few studies
Externí odkaz:
https://doaj.org/article/8a04be27587840df8c9f2b5d4ebd7f27
Autor:
Amy A. Kirkwood, Nicholas Goulden, John Moppett, Sujith Samarasinghe, Jon Mee, Rachael Hough, Pamela R. Kearns, Sarah Lawson, Clare J. Rowntree, Ajay Vora
Publikováno v:
Blood. 140:516-518
Autor:
David I Marks, Amy A Kirkwood, Clare J Rowntree, Melanie Aguiar, Katharine E Bailey, Brendan Beaton, Paul Cahalin, Anna Z Castleton, Laura Clifton-Hadley, Mhairi Copland, Anthony H Goldstone, Richard Kelly, Emma Lawrie, SooWah Lee, Andrew K McMillan, Mary Frances McMullin, Tobias F Menne, Rachel J Mitchell, Anthony V Moorman, Bela Patel, Pip Patrick, Paul Smith, David Taussig, Deborah Yallop, Krisztina Zuborne Alapi, Adele K Fielding
Publikováno v:
Marks, D I, Kirkwood, A A, Rowntree, C J, Aguiar, M, Bailey, K E, Beaton, B, Cahalin, P, Castleton, A Z, Clifton-Hadley, L, Copland, M, Goldstone, A H, Kelly, R, Lawrie, E, Lee, S, McMillan, A K, McMullin, M F, Menne, T F, Mitchell, R J, Moorman, A V, Patel, B, Patrick, P, Smith, P, Taussig, D, Yallop, D, Alapi, K Z & Fielding, A K 2022, ' Addition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial ', The Lancet Haematology, vol. 9, no. 4, pp. e262-e275 . https://doi.org/10.1016/S2352-3026(22)00038-2
BACKGROUND: Treatment for adults with acute lymphoblastic leukaemia requires improvement. UKALL14 was a UK National Cancer Research Institute Adult ALL group study that aimed to determine the benefit of adding the anti-CD20 monoclonal antibody, ritux
Autor:
Christine J. Harrison, Elli Papaemmanuil, Ellie Butler, Emilio Barretta, Anthony V. Moorman, Daniel Leongamornlert, Andrew McMillan, Nick Morley, Thomas Creasey, Laura Clifton-Hadley, Tobias Menne, Amy A Kirkwood, Clare J. Rowntree, Bela Patel, Adele K. Fielding, Sarra Ryan, David I. Marks, Pip Patrick
Publikováno v:
Haematologica. 107:2051-2063
Despite being predominantly a childhood disease, the incidence of acute lymphoblastic leukemia (ALL) has a second peak in adults aged 60 years and over. These older adults fare extremely poorly with existing treatment strategies and very few studies
Autor:
Elli Papaemmanuil, Amy A Kirkwood, Andrew McMillan, Eleanor J. Ward, David I. Marks, Amir Enshaei, Claire Schwab, Daniel Leongamornlert, Pip Patrick, Ellie Butler, Emilio Barretta, Christine J. Harrison, Clare J. Rowntree, Laura Clifton-Hadley, Tom Creasey, Bela Patel, Adele K. Fielding, Anthony V. Moorman, Tobias Menne, Katie Twentyman
Publikováno v:
Leukemia. 36:625-636
Chromosomal abnormalities are established prognostic markers in adult ALL. We assessed the prognostic impact of established chromosomal abnormalities and key copy number alterations (CNA) among 652 patients with B-cell precursor ALL treated on a mode
Autor:
Pip Patrick, Clare J. Rowntree, Andrew McMillan, Emma Lawrie, Krisztina Zuborne Alapi, Bela Patel, Laura Clifton-Hadley, Emilio Barretta, Adele K. Fielding, Rachel J. Mitchell, Anthony V. Moorman, Tobias F. Menne, Elli Papaemmanuil, David I. Marks, Soo Wah Lee, Amy A Kirkwood, Daniel Leongamornlert, Nahid Zareian
Publikováno v:
Blood Adv
IKZF1 deletions (ΔIKZF1) are commonly detected in B-precursor acute lymphoblastic leukemia (ALL; B-ALL) and are widely assumed to have a significant impact on outcome. We compared the ability of multiplex ligand-dependent probe amplification (MLPA)
Autor:
Bela Patel Wrench, Amy A. Kirkwood, Krisztina Zuborne Alapi, Laura Clifton-Hadley, SooWah Lee, David I. Marks, Anthony V. Moorman, Nicholas J. Morley, Pip Patrick, Zaynab Rana, Clare J. Rowntree, John A. Snowden, Adele K. Fielding
Publikováno v:
Blood. 140:6125-6126
Autor:
Anthony V, Moorman, Emilio, Barretta, Ellie R, Butler, Eleanor J, Ward, Katie, Twentyman, Amy A, Kirkwood, Amir, Enshaei, Claire, Schwab, Tom, Creasey, Daniel, Leongamornlert, Elli, Papaemmanuil, Pip, Patrick, Laura, Clifton-Hadley, Bela, Patel, Tobias, Menne, Andrew K, McMillan, Christine J, Harrison, Clare J, Rowntree, David I, Marks, Adele K, Fielding
Publikováno v:
Leukemia. 36(3)
Chromosomal abnormalities are established prognostic markers in adult ALL. We assessed the prognostic impact of established chromosomal abnormalities and key copy number alterations (CNA) among 652 patients with B-cell precursor ALL treated on a mode