Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Clare F. Quarnstrom"'
Autor:
Christine E. Nelson, Emily A. Thompson, Clare F. Quarnstrom, Kathryn A. Fraser, Davis M. Seelig, Siddheshvar Bhela, Brandon J. Burbach, David Masopust, Vaiva Vezys
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3092-3104.e5 (2019)
Summary: The immune system adapts to constitutive antigens to preserve self-tolerance, which is a major barrier for anti-tumor immunity. Antigen-specific reversal of tolerance constitutes a major goal to spur therapeutic applications. Here, we show t
Externí odkaz:
https://doaj.org/article/f2ed85c1525a4117a9fddec93eec624d
Autor:
Pamela C. Rosato, Sahar Lotfi-Emran, Vineet Joag, Sathi Wijeyesinghe, Clare F. Quarnstrom, Hanna N. Degefu, Rebecca Nedellec, Jason M. Schenkel, Lalit K. Beura, Lars Hangartner, Dennis R. Burton, David Masopust
Publikováno v:
Mucosal Immunology. 16:17-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2441ad98b2df16edd803962fe2dc62d0
https://doi.org/10.1016/j.mucimm.2022.11.004
https://doi.org/10.1016/j.mucimm.2022.11.004
Autor:
Andrew G. Soerens, Marco Künzli, Clare F. Quarnstrom, Milcah C. Scott, Lee Swanson, JJ. Locquiao, Hazem E. Ghoneim, Dietmar Zehn, Benjamin Youngblood, Vaiva Vezys, David Masopust
Publikováno v:
Nature. 614:762-766
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3af58a6302627c094791006edb721b25
https://doi.org/10.1038/s41586-022-05626-9
https://doi.org/10.1038/s41586-022-05626-9
Autor:
Lalit K. Beura, Milcah C. Scott, Mark J. Pierson, Vineet Joag, Sathi Wijeyesinghe, Matthew R. Semler, Clare F. Quarnstrom, Kathleen Busman-Sahay, Jacob D. Estes, Sara E. Hamilton, Vaiva Vezys, David H. O’Connor, David Masopust
Publikováno v:
The Journal of Immunology. 209:1691-1702
Lymphocytic choriomeningitis virus (LCMV) is the prototypic arenavirus and a natural mouse pathogen. LCMV-Armstrong, an acutely resolved strain, and LCMV-clone 13, a mutant that establishes chronic infection, have provided contrasting infection model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf94d5d42089b8c93cf71954c575e4d5
https://doi.org/10.4049/jimmunol.2200320
https://doi.org/10.4049/jimmunol.2200320
Autor:
Marco Künzli, Stephen D. O’Flanagan, Madeleine LaRue, Poulami Talukder, Thamotharampillai Dileepan, Andrew G. Soerens, Clare F. Quarnstrom, Sathi Wijeyesinghe, Yanqi Ye, Justine McPartlan, Jason S. Mitchell, Christian W. Mandl, Richard Vile, Marc K. Jenkins, Rafi Ahmed, Vaiva Vezys, Jasdave Chahal, David Masopust
Respiratory tract resident memory T cells (Trm), typically generated by local vaccination or infection, can accelerate control of pulmonary infections that evade neutralizing antibody. It is unknown whether mRNA vaccination establishes respiratory Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959e5f9e405bb7978a3afd9fcfa18887
https://doi.org/10.1101/2022.06.02.494574
https://doi.org/10.1101/2022.06.02.494574
Autor:
Traci Legere, Pradeep B. J. Reddy, Korey A. Walter, Bali Pulendran, Prabhu S. Arunachalam, Shankar Subramaniam, Florian Wimmers, Madeleine K D Scott, Celia C. LaBranche, Bertrand Z. Yeung, John P. Vasilakos, Venkata S. Bollimpelli, Samantha L. Burton, Sailaja Gangadhara, Sudhir Pai Kasturi, Shakti Gupta, Cynthia A. Derdeyn, Caroline Petitdemange, Pamela A. Kozlowski, David C. Montefiori, Tiffany M. Styles, Thomas J. Ketas, John P. Moore, Chil Yong Kang, Rama Rao Amara, Eric Hunter, George M. Shaw, Purvesh Khatri, Mark A. Tomai, Anthony Tsai, David Masopust, Vineet Joag, Clare F. Quarnstrom, Tysheena P. Charles
Publikováno v:
Nature Medicine
Recent efforts toward an HIV vaccine focus on inducing broadly neutralizing antibodies, but eliciting both neutralizing antibodies (nAbs) and cellular responses may be superior. Here, we immunized macaques with an HIV envelope trimer, either alone to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ad3f6afa379c5c408d930aefb7aaee
https://doi.org/10.1038/s41591-020-0858-8
https://doi.org/10.1038/s41591-020-0858-8
Autor:
Kathryn A. Fraser, Emily A. Thompson, Clare F. Quarnstrom, Davis M. Seelig, Vaiva Vezys, Siddheshvar Bhela, Brandon J. Burbach, David Masopust, Christine E. Nelson
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3092-3104.e5 (2019)
Cell reports
Cell reports
SUMMARY The immune system adapts to constitutive antigens to preserve self-tolerance, which is a major barrier for anti-tumor immunity. Antigen-specific reversal of tolerance constitutes a major goal to spur therapeutic applications. Here, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a21823669830aea0c1d9d71eb3b0527
http://www.sciencedirect.com/science/article/pii/S2211124719310782
http://www.sciencedirect.com/science/article/pii/S2211124719310782
Autor:
Vaiva Vezys, Emily A. Thompson, Lauren J. Mills, Jennifer L. McCurtain, Clare F. Quarnstrom, Christine E. Nelson, Brian T. Fife, Davis M. Seelig, Siddheshvar Bhela
Publikováno v:
Proceedings of the National Academy of Sciences. 116:2640-2645
Established T cell dysfunction is a barrier to antitumor responses, and checkpoint blockade presumably reverses this. Many patients fail to respond to treatment and/or develop autoimmune adverse events. The underlying reason for T cell responsiveness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c139765efe12a1d26a3bc42d812d1d
https://doi.org/10.1073/pnas.1810326116
https://doi.org/10.1073/pnas.1810326116
Autor:
Vineet Joag, Stephen D O'Flanagan, Joshua M. Thiede, Clare F. Quarnstrom, Clayton K. Mickelson, Marc K. Jenkins, J. Michael Stolley, William E. Matchett, Tyler D. Bold, David Masopust, Michelle N Vu, Vaiva Vezys, Frances K. Shepherd, Vineet D. Menachery, Jennifer A Walter, Samuel Becker, Sathi Wijeyesinghe, Ryan A. Langlois, Eyob Weyu, Andrew G. Soerens
Publikováno v:
bioRxiv
J Immunol
J Immunol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing Abs target the receptor binding domain of the spike (S) protein, a focus of successful vaccine efforts. Concerns have arisen that S-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c205ab28b707a597b35f7b87b967bd
https://pubmed.ncbi.nlm.nih.gov/33948591
https://pubmed.ncbi.nlm.nih.gov/33948591
Autor:
J. Michael Stolley, Peter J. Southern, Siddheshvar Bhela, Thamotharampillai Dileepan, Maxim C.-J. Cheeran, Vineet Joag, Marc K. Jenkins, Sathi Wijeyesinghe, Joshua M. Thiede, Luca Schifanella, Jules A. Sangala, Clare F. Quarnstrom, Geoffrey T. Hart, Stephen D O'Flanagan, Sung-Wook Hong, Venkatramana D. Krishna, William E. Matchett, Noah V. Gavil, David Masopust, Sailaja Gangadhara, Tyler D. Bold, Eyob Weyu, Ryan A. Langlois, Vaiva Vezys, Rama Rao Amara, Andrew G. Soerens
Publikováno v:
J Immunol
The magnitude of SARS-CoV-2–specific T cell responses correlates inversely with human disease severity, suggesting T cell involvement in primary control. Whereas many COVID-19 vaccines focus on establishing humoral immunity to viral spike protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dea03208cbb13c98035ec2035630766
https://pubmed.ncbi.nlm.nih.gov/33441437
https://pubmed.ncbi.nlm.nih.gov/33441437