Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Clare F, McCoy"'
Autor:
Diarmaid J. Murphy, Yahya H. Dallal Bashi, Clare F. McCoy, Peter Boyd, Leeanne Brown, François Martin, Nicole McMullen, Kyle Kleinbeck, Bindi Dangi, Patrick Spence, Bashir Hansraj, Bríd Devlin, R. Karl Malcolm
Publikováno v:
International Journal of Pharmaceutics: X, Vol 4, Iss , Pp 100112- (2022)
We have previously reported a multipurpose silicone elastomer vaginal ring providing sustained release of dapivirine (an antiretroviral) and levonorgestrel (a progestin) for HIV prevention and hormonal contraception. During initial development, issue
Externí odkaz:
https://doaj.org/article/98d3571e295347d6bdcf8ce0b2fa4992
Autor:
Carolina Herrera, Mackenzie L. Cottrell, John Prybylski, Angela D.M. Kashuba, Ronald S. Veazey, Javier García-Pérez, Natalia Olejniczak, Clare F. McCoy, Paul Ziprin, Nicola Richardson-Harman, José Alcami, Karl R. Malcolm, Robin J. Shattock
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104409- (2022)
Summary: Non-human primates (NHP) are widely used for the pre-clinical assessment of antiretrovirals (ARVs) for HIV treatment and prevention. However, the utility of these models is questionable given the differences in ARV pharmacology between human
Externí odkaz:
https://doaj.org/article/144a3fe3df8c4787bcf5151998c7bce4
Autor:
Clare F. McCoy, Patrick Spence, Yahya H. Dallal Bashi, Diarmaid J. Murphy, Peter Boyd, Bindi Dangi, Tiffany Derrick, Bríd Devlin, Kyle Kleinbeck, R. Karl Malcolm
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100081- (2021)
Vaginal rings releasing antiretrovirals – either alone or in combination with contraceptive progestins – are being developed for prevention of human immunodeficiency virus (HIV) transmission via vaginal sex. Following Phase I trials, significant
Externí odkaz:
https://doaj.org/article/33201504c4cc4078bdec85999ffab7fe
Autor:
Yahya H. Dallal Bashi, Diarmaid J. Murphy, Clare F. McCoy, Peter Boyd, Leeanne Brown, Matthew Kihara, François Martin, Nicole McMullen, Kyle Kleinbeck, Bindi Dangi, Patrick Spence, Bashir Hansraj, Brid Devlin, R. Karl Malcolm
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100091- (2021)
A dapivirine-releasing silicone elastomer vaginal ring for reducing women's risk of HIV acquisition has recently been approved. A next-generation multipurpose vaginal ring releasing dapivirine and levonorgestrel is currently in development, offering
Externí odkaz:
https://doaj.org/article/b7f3a5a85e75423d8f768cfe40fff198
Autor:
Carolina, Herrera, Mackenzie L, Cottrell, John, Prybylski, Angela D M, Kashuba, Ronald S, Veazey, Javier, García-Pérez, Natalia, Olejniczak, Clare F, McCoy, Paul, Ziprin, Nicola, Richardson-Harman, José, Alcami, Karl R, Malcolm, Robin J, Shattock
Publikováno v:
iScience. 25(6)
Non-human primates (NHP) are widely used for the pre-clinical assessment of antiretrovirals (ARVs) for HIV treatment and prevention. However, the utility of these models is questionable given the differences in ARV pharmacology between humans and mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de0b86bf1a1fd31b3a1d448b6e343805
https://pubmed.ncbi.nlm.nih.gov/35663021
https://pubmed.ncbi.nlm.nih.gov/35663021
Autor:
Clare F, McCoy, David C, Apperley, Bruce, Variano, Heather, Sussman, Daniel, Loeven, Peter, Boyd, R Karl, Malcolm
Publikováno v:
International journal of pharmaceutics. 548(1)
Steroid molecules have a long history of incorporation into silicone elastomer materials for controlled release drug delivery applications. Previously, based on in vitro release testing and drug content analysis, we demonstrated indirectly that the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::474eda57a7aeaa1040da2886fca5929e
https://pubmed.ncbi.nlm.nih.gov/30016672
https://pubmed.ncbi.nlm.nih.gov/30016672