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pro vyhledávání: '"Clare Elizabeth Pritchard"'
Publikováno v:
Nucleic Acids Research. 25:3403-3407
The requirement for Watson-Crick base pairing surrounding a nick in duplex DNA to be sealed by DNA ligase is the basis for oligonucleotide ligation assays that distinguish single base mutations in DNA targets. Experiments in a model system demonstrat
Publikováno v:
Current opinion in chemical biology. 2(3)
The large amount of DNA sequence information produced in recent years has created a need for high-throughput methods in biology and genetics. These include sequencing, comparing gene sequences and genotyping. DNA arrays promise a highly parallel mean