Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Clare Eckold"'
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity
Autor:
Clare Eckold, Cassandra L. R. vanDoorn, Rovina Ruslami, Katharina Ronacher, Anca‐Lelia Riza, Suzanne vanVeen, Ji‐Sook Lee, Vinod Kumar, Sarah Kerry‐Barnard, Stephanus T. Malherbe, Léanie Kleynhans, Kim Stanley, Simone A. Joosten, Julia A Critchley, Philip C. Hill, Reinout vanCrevel, Cisca Wijmenga, Mariëlle C. Haks, Mihai Ioana, Bachti Alisjahbana, Gerhard Walzl, Tom H. M. Ottenhoff, Hazel M. Dockrell, Eleonora Vianello, Jacqueline M. Cliff, the TANDEM Consortium$
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 9, Pp n/a-n/a (2023)
Abstract Background People with diabetes are more likely to develop tuberculosis (TB) and to have poor TB‐treatment outcomes than those without. We previously showed that blood transcriptomes in people with TB‐diabetes (TB‐DM) co‐morbidity ha
Externí odkaz:
https://doaj.org/article/229588c3fbff41bc8ad7133cef9a8c93
Autor:
Anke Nijhuis, Arti Sikka, Orli Yogev, Lili Herendi, Cristina Balcells, Yurui Ma, Evon Poon, Clare Eckold, Gabriel N. Valbuena, Yuewei Xu, Yusong Liu, Barbara Martins da Costa, Michael Gruet, Chiharu Wickremesinghe, Adrian Benito, Holger Kramer, Alex Montoya, David Carling, Elizabeth J. Want, Yann Jamin, Louis Chesler, Hector C. Keun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The prognosis of high-risk neuroblastoma is poor despite the availability of multimodal treatment. Here the authors show that high-risk neuroblastoma is sensitive to indisulam, a selective degrader of the splicing factor RBM39 through the dual target
Externí odkaz:
https://doaj.org/article/c91ed6203d624310b8e94805ee7888bd
Autor:
Cassandra L.R. van Doorn, Clare Eckold, Katharina Ronacher, Rovina Ruslami, Suzanne van Veen, Ji-Sook Lee, Vinod Kumar, Sarah Kerry-Barnard, Stephanus T. Malherbe, Léanie Kleynhans, Kim Stanley, Philip C. Hill, Simone A. Joosten, Reinout van Crevel, Cisca Wijmenga, Julia A. Critchley, Gerhard Walzl, Bachti Alisjahbana, Mariëlle C. Haks, Hazel M. Dockrell, Tom H.M. Ottenhoff, Eleonora Vianello, Jacqueline M. Cliff
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104173- (2022)
Summary: Background: Globally, the tuberculosis (TB) treatment success rate is approximately 85%, with treatment failure, relapse and death occurring in a significant proportion of pulmonary TB patients. Treatment success is lower among people with d
Externí odkaz:
https://doaj.org/article/d8a5f598ec4c4e9383b52b8fc1ff3690
Autor:
Thatcha Yimthin, Jacqueline Margaret Cliff, Rungnapa Phunpang, Peeraya Ekchariyawat, Taniya Kaewarpai, Ji-Sook Lee, Clare Eckold, Megan Andrada, Ekkachai Thiansukhon, Kittisak Tanwisaid, Somchai Chuananont, Chumpol Morakot, Narongchai Sangsa, Wirayut Silakun, Sunee Chayangsu, Noppol Buasi, Nicholas Day, Ganjana Lertmemongkolchai, Wasun Chantratita, T. Eoin West, Narisara Chantratita
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 8-18 (2021)
Melioidosis is an often lethal tropical disease caused by the Gram-negative bacillus, Burkholderia pseudomallei. The study objective was to characterize transcriptomes in melioidosis patients and identify genes associated with outcome. Whole blood RN
Externí odkaz:
https://doaj.org/article/9caf47893d6446638d55ddc34d26bc7d
Autor:
Yolandi Swart, Caitlin Uren, Clare Eckold, Jacqueline M Cliff, Stephanus T Malherbe, Katharina Ronacher, Vinod Kumar, Cisca Wijmenga, Hazel M Dockrell, Reinout van Crevel, Gerhard Walzl, Léanie Kleynhans, Marlo Möller
The validation of genome-wide association signals for tuberculosis (TB) susceptibility and the development of type 2 diabetes (T2D) across diverse populations remain problematic. The ancestry-specific variants (coding and non-coding) that contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b45c3c54a9ff8f6dab7f91618f9a72a9
https://doi.org/10.1101/2022.10.19.512814
https://doi.org/10.1101/2022.10.19.512814
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity
Autor:
Clare Eckold, Cassandra L.R. van Doorn, Rovina Ruslami, Katharina Ronacher, Anca-Lelia Riza, Suzanne van Veen, Ji-Sook Lee, Vinod Kumar, Sarah Kerry-Barnard, Stephanus T. Malherbe, Léanie Kleynhans, Kim Stanley, Simone A. Joosten, Julia A Critchley, Philip C. Hill, Reinout van Crevel, Cisca Wijmenga, Mariëlle C. Haks, Mihai Ioana, Bachti Alisjahbana, Gerhard Walzl, Tom H. M. Ottenhoff, Hazel M. Dockrell, Eleonora Vianello, Jacqueline M. Cliff
BackgroundPeople with diabetes are more likely to develop tuberculosis (TB) and to have poor TB treatment outcomes than those without. We previously showed that blood transcriptomes in people with TB-diabetes (TB-DM) co-morbidity have excessive infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46dcf055b3bcc0eb78b328e644d49e20
https://doi.org/10.1101/2022.02.07.22269422
https://doi.org/10.1101/2022.02.07.22269422
Autor:
Hazel M. Dockrell, Jacqueline M. Ratter, Mardiana Marzuki, Elise J. Smolders, Mihai G. Netea, Julia Böhme, Rob J.W. Arts, Clare Eckold, Corina N. A. M. van den Heuvel, Jinmiao Chen, Bastiaan A. Blok, Karen Wei Weng Teng, Valerie A. C. M. Koeken, Rinke Stienstra, Amit Singhal, Evan W. Newell, Jacqueline M. Cliff, Reinout van Crevel, Ekta Lachmandas
Publikováno v:
The Journal of Infectious Diseases
The Journal of Infectious Diseases, 220, 139-150
The Journal of Infectious Diseases 220 (2019) 1
The Journal of Infectious Diseases, 220(1), 139-150
The Journal of Infectious Diseases, 220, 1, pp. 139-150
The Journal of Infectious Diseases, 220, 139-150
The Journal of Infectious Diseases 220 (2019) 1
The Journal of Infectious Diseases, 220(1), 139-150
The Journal of Infectious Diseases, 220, 1, pp. 139-150
Background Metformin, the most widely administered diabetes drug, has been proposed as a candidate adjunctive host-directed therapy for tuberculosis, but little is known about its effects on human host responses to Mycobacterium tuberculosis. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16277f751b28b9e434bab443a16e33c
https://doi.org/10.1093/infdis/jiz064
https://doi.org/10.1093/infdis/jiz064
Autor:
Lili Herendi, Hector C. Keun, Adrian Benito, Yusong Liu, Holger Kramer, Barbara Martins da Costa, David Carling, Louis Chesler, Yann Jamin, Arti Sikka, Eirini Kouloura, Gabriel N. Valbuena, Orli Yogev, Clare Eckold, Evon Poon, Elizabeth J. Want, Alex Montoya, Anke Nijhuis
Neuroblastoma is the most common solid tumour in childhood and prognosis remains poor for high-risk cases despite the use of multimodal treatment. Analysis of public drug sensitivity data showed neuroblastoma lines to be particularly sensitive to ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3430a7ff5212d8bf937972bd8160617b
https://doi.org/10.1101/2020.12.18.423403
https://doi.org/10.1101/2020.12.18.423403
Autor:
T. Eoin West, Wasun Chantratita, Noppol Buasi, Peeraya Ekchariyawat, Ji-Sook Lee, Wirayut Silakun, Somchai Chuananont, Sunee Chayangsu, Ganjana Lertmemongkolchai, Narongchai Sangsa, Megan Andrada, Kittisak Tanwisaid, Narisara Chantratita, Ekkachai Thiansukhon, Taniya Kaewarpai, Clare Eckold, Nicholas P. J. Day, Rungnapa Phunpang, Chumpol Morakot, Thatcha Yimthin, Jacqueline M. Cliff
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Supplemental materials: available online at https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1858176#supplemental-material-section Copyright © 2021 The Author(s). Melioidosis is an often lethal tropical disease caused by the Gram-negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06ae7dcd24448178974f9d1ac5a02fa
Autor:
Alexander Pym, Stephen H. Gillespie, Dimitrios Evangelopoulos, Isobella Honeyborne, Marc Lipman, Timothy D. McHugh, Clare Eckold
Publikováno v:
The European respiratory journal. 45(6)
Small RNA (smRNA) is a diverse family of translation regulation molecules, which includes microRNA (miRNA). Changes in miRNA have been reported in association with respiratory disease [1] and in mycobacterial infection [2]. Studies have measured conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4a3e0989afae0c67b402dae384774e
https://pubmed.ncbi.nlm.nih.gov/25745052
https://pubmed.ncbi.nlm.nih.gov/25745052