Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Clare E. Sefton"'
Autor:
Karen Oldman, Mark Pilling, Martin R. Brown, Chris Pollard, Najah Abi-Gerges, Clare E. Sefton, Amy Pointon, Helen Garside
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 83:1-15
Cardiovascular toxicity is a prominent reason for failures in drug development, resulting in the demand for assays that can predict this liability in early drug discovery. We investigated whether iCell® cardiomyocytes have utility as an early QT/TdP
Autor:
Najah, Abi-Gerges, Amy, Pointon, Karen L, Oldman, Martin R, Brown, Mark A, Pilling, Clare E, Sefton, Helen, Garside, Christopher E, Pollard
Publikováno v:
Journal of pharmacological and toxicological methods. 83
Cardiovascular toxicity is a prominent reason for failures in drug development, resulting in the demand for assays that can predict this liability in early drug discovery. We investigated whether iCell® cardiomyocytes have utility as an early QT/TdP
Publikováno v:
Molecular Informatics. 31:365-368
Matched molecular pairs analysis (MMPA)1,2 is an inverse quantitative structure activity relationship (QSAR) technique that is rapidly gaining popularity in the retrospective analysis of large experimental datasets.3,4 While much of the recent focus
Autor:
Matthew Skinner, Jean-Pierre Valentin, Alexander R. Harmer, Clare E. Sefton, Chris Pollard, Syril Pettit
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 64:e7