Výsledky vyhledávání - "Clare E. Alexander"

Tissue Requirements for Establishing Long-Term CD4+ T Cell–Mediated Immunity following Leishmania donovani Infection

Autor: Christian R. Engwerda, Clare E. Alexander, Kylie R. James, Meru Sheel, Amanda C. Stanley, Fabian de Labastida Rivera, Shannon E. Best, Fiona H. Amante, Alexander Mulherin, Paul M. Kaye, Marcela Montes de Oca, Ashraful Haque, Rebecca J. Faleiro, Patrick T. Bunn

Publikováno v: The Journal of Immunology. 192:3709-3718

Organ-specific immunity is a feature of many infectious diseases, including visceral leishmaniasis caused by Leishmania donovani. Experimental visceral leishmaniasis in genetically susceptible mice is characterized by an acute, resolving infection in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fdf57a5afd5f0a9d07abcec7c5c225
https://doi.org/10.4049/jimmunol.1300768

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AIRE's CARD Revealed, a New Structure for Central Tolerance Provokes Transcriptional Plasticity

Autor: Hamish S. Scott, Ana Rebane, Simona W. Rossi, Clare E. Alexander, Brian J. Ferguson, Pärt Peterson, Joyce Wong, Eric J. Jenkinson, Ingrid Liiv, Catherine L. Worth, Anne Cooke, Martti Laan, Graham Anderson, Tina Rich

Publikováno v: Journal of Biological Chemistry. 283:1723-1731

Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive clones. It is now known that the autoimmune regulator protein (AIRE), which is expressed in thymic medullary epithelial cells, plays a key role in reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4db5423183a57026c317347e944af8
https://doi.org/10.1074/jbc.m707211200

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Evidence for the receipt of DNA damage stimuli by PML nuclear domains

Autor: CL Dovey, Archana Varadaraj, Brian J. Ferguson, Andrew H. Wyllie, L.N. Laredj, Clare E. Alexander, N Lubben, Tina Rich

Publikováno v: The Journal of Pathology. 211:471-480

Promyelocytic leukaemia nuclear domains (PML-NDs) comprise a shell of PML protein and many labile cargo proteins. The nature of their cargo, their juxtaposition to foci of damaged DNA following ionizing radiation (IR), and the altered DNA damage resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfca6e216f88ed3e31601e3d8316a89
https://doi.org/10.1002/path.2126

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CD95 is required for the early control of parasite burden in the liver ofLeishmania donovani-infected mice

Autor: Clare E. Alexander, Paul M. Kaye, Christian R. Engwerda

Publikováno v: European Journal of Immunology. 31:1199-1210

In this study we show an increased incidence of T cell apoptosis in the liver and spleen of mice infected with Leishmania donovani. T cells from L. donovani-infected mice were found to be increasingly susceptible to CD95-mediated apoptosis in vitro,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b20f70b1cc0cb51c91921eba6c2303d0
https://doi.org/10.1002/1521-4141(200104)31:4<1199::aid-immu1199>3.0.co

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Interactions on mixing litters from beneath Sitka spruce and Scots pine and the effects on microbial activity and N-mineralization

Autor: B. L. Williams, Clare E. Alexander

Publikováno v: Soil Biology and Biochemistry. 23:71-75

Columns packed with loose needle litters from pure Sitka spruce (SS), Scots pine (SP) and a 1:1 mixture (SS & SP) were leached for 21 weeks with distilled water. At the start the SP litter had smaller microbial biomass C and N contents, but a signifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99ef0f465a36f741dbb3563f7097cbc5
https://doi.org/10.1016/0038-0717(91)90164-f

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Analysis of Antigen Reactive T-Cells

Autor: Malgosia K. Matyszak, Natasha Telyatnikova, Clare E. Alexander, Richard C. Duggleby, J. S. Hill Gaston, Jane C. Goodall

Publikováno v: Arthritis Research ISBN: 9781588299185

Because antigen-specific cells are the central coordinators of the immune response to infectious organisms, and the principal effector cells in autoimmune disease, there are many circumstances in which investigators may wish to examine the T-cell res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71c119cf2fda8cba51aa4eb6a24d41b8
https://doi.org/10.1007/978-1-59745-402-5_5

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Distinct Roles for Lymphotoxin-α and Tumor Necrosis Factor in the Control of Leishmania donovani Infection

Autor: Christian R. Engwerda, Simona Stäger, Paul M. Kaye, Clare E. Alexander, Manabu Ato, Amanda C. Stanley

Tumor necrosis factor (TNF) is critical for the control of visceral leishmaniasis caused by Leishmania donovani. However, the role of the related cytokine lymphotoxin (LT) alpha in this infection is unknown. Here we report that C57BL/6 mice deficient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501b2e68658d297782c8f879e3bc04f6
https://europepmc.org/articles/PMC1618729/

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SCANNING ELECTRON MICROSCOPY OF CRYOFIXED MYCORRHIZAS OF SITKA SPRUCE, PICE A SITCHENSIS (BONG.) CARR.: A COMPARISON WITH CRITICAL POINT-DRIED MATERIAL

Autor: D. Jones, Clare E. Alexander, W. J. McHARDY

Publikováno v: New Phytologist. 105:613-617

Summary Critical point-drying is the standard method of preparation for scanning electron microscope studies of mycorrhizas. However, a number of recent studies on various biological specimens have shown disadvantages associated with this technique.

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https://doi.org/10.1111/j.1469-8137.1987.tb00899.x

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Akademický článek

Civilization, Modernity and Europe: The Making and Unmaking of a Conceptual Unity.

Autor: MURRAY‐MILLER, G. A. V. I. N.¹

Publikováno v: History. Jul2018, Vol. 103 Issue 356, p418-433. 16p.

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