Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification

Autor: Valérie Combaret, A. Valent, Bárbara Marques, Ales Vicha, Tommy Martinsson, N. Van Roy, Riccardo Haupt, Gian Paolo Tonini, Gudrun Schleiermacher, Alberto Garaventa, M. Jeison, Stefano Parodi, Peter F. Ambros, Claudio Gambini, Giovanni Erminio, J.A. Kohler, I.M. Ambros, Nicole Gross, John Lunec, Raffaella Defferrari, Rosa Noguera, Ana P. Berbegall, Jérôme Couturier, Clare Bedwell, Deborah A. Tweddle, Klaus Beiske, Jean Bénard, Eva Villamón, Katia Mazzocco, Nick Bown

Publikováno v: BRITISH JOURNAL OF CANCER
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
British Journal of Cancer, vol. 112, no. 2, pp. 290-295
British Journal of Cancer
British Journal of Cancer 112 (2015): 290–295. doi:10.1038/bjc.2014.557
info:cnr-pdr/source/autori:Defferrari R, Mazzocco K, Ambros IM, Ambros PF, Bedwell C, Beiske K, Bénard J, Berbegall AP, Bown N, Combaret V, Couturier J, Erminio G, Gambini C, Garaventa A, Gross N, Haupt R, Kohler J, Jeison M, Lunec J, Marques B, Martinsson T, Noguera R, Parodi S, Schleiermacher G, Tweddle DA, Valent A, Van Roy N, Vicha A, Villamon E, Tonini GP./titolo:Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification./doi:10.1038%2Fbjc.2014.557/rivista:British Journal of Cancer/anno:2015/pagina_da:290/pagina_a:295/intervallo_pagine:290–295/volume:112

Background: The prognostic impact of segmental chromosome alterations (SCAs) in children older than 1 year, diagnosed with localised unresectable neuroblastoma (NB) without MYCN amplification enrolled in the European Unresectable Neuroblastoma (EUNB)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cab5a88345e777e64001e14240459b4
https://doi.org/10.1038/bjc.2014.557

A de novo 4q34 interstitial deletion of at least 9.3 Mb with no discernible phenotypic effect

Autor: Sarju G. Mehta, Kristin M. Abbott, Simon Zwolinski, Lionel Willatt, Leeanne Sparnon, Ingrid Simonic, Elizabeth Selkirk, Mark S. Bateman, John C. K. Barber, Clare Bedwell

Publikováno v: American Journal of Medical Genetics Part A. :1764-1769

Cytogenetically visible imbalances without phenotypic effect are still rare despite the extent of large-scale copy number variation in the normal population revealed by array CGH. Here we report on a phenotypically normal 30-year-old female with a de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0407c7fab9c28fca7c734b0dfe1506
https://doi.org/10.1002/ajmg.a.33426

A multilocus technique for risk evaluation of patients with neuroblastoma

Autor: Alexander Valent, Gian Paolo Tonini, Bárbara Marques, Ales Vicha, Ruth Ladenstein, Gerhard Aigner, Jérôme Couturier, Clare Bedwell, Nicole Gross, Ulrike Pötschger, Mario Drobics, Bettina Brunner, Gabriele Amann, Deborah A. Tweddle, Raymond L. Stallings, Frank Speleman, Valérie Combaret, Sandra Preuner, Tommy Martinsson, Andrea Ziegler, Jean Bénard, Klaus Beiske, Marta Jeison, Robert J.L. Schuit, Inge M. Ambros, Peter F. Ambros, John Lunec, Katia Mazzocco, Nadine Van Roy, Raffaella Defferrari, Nick Bown, Rosa Noguera, Eva Villamón, Gudrun Schleiermacher

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 17(4)

Purpose: Precise and comprehensive analysis of neuroblastoma genetics is essential for accurate risk evaluation and only pangenomic/multilocus approaches fulfill the present-day requirements. We present the establishment and validation of the PCR-bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0315b067f3b0d85dc5aa437d75ee29b9
https://pubmed.ncbi.nlm.nih.gov/21325297

Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project.

Autor: Schleiermacher, G.¹, Mosseri, V.², London, W. B.³, Maris, J. M.⁴, Brodeur, G. M.⁴, Attiyeh, E.⁴, Haber, M.⁵, Khan, J.⁶, Nakagawara, A.⁷, Speleman, F.⁸, Noguera, R.⁹, Tonini, G. P.¹⁰, Fischer, M.¹¹, Ambros, I.¹², Monclair, T.¹³, Matthay, K. K.¹⁴, Ambros, P.¹², Cohn, S. L.¹⁵, Pearson, A. D. J.¹⁶

Publikováno v: British Journal of Cancer. 10/9/2012, Vol. 107 Issue 8, p1418-1422. 5p. 1 Diagram, 3 Charts, 1 Graph.

Auf Knopfdruck

Autor: Marta Marková

Oskar Seidenglanz - vom einfachen Lehrling aus dem 9. Wiener Bezirk, der sich zunächst als Wehrmachtsoffizier in Sammelwohnungen von deportierten jüdischen Familien einnistet, um sich nach dem Krieg als vermeintlich jüdischer Geschäftsmann in ein