Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Clare Bao"'
Autor:
Scott J Cameron, Craig N Morrell, Clare Bao, AnneMarie F Swaim, Annabelle Rodriguez, Charles J Lowenstein
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144372 (2015)
High density lipoprotein has anti-inflammatory effects in addition to mediating reverse cholesterol transport. While many of the chronic anti-inflammatory effects of high density lipoprotein (HDL) are attributed to changes in cell adhesion molecules,
Externí odkaz:
https://doaj.org/article/3649550db0bd4a0ea3f44214632835ab
Autor:
Annabelle Rodriguez, Clare Bao, Craig N. Morrell, Scott J. Cameron, AnneMarie F. Swaim, Charles J. Lowenstein
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0144372 (2015)
PLoS ONE, Vol 10, Iss 12, p e0144372 (2015)
High density lipoprotein has anti-inflammatory effects in addition to mediating reverse cholesterol transport. While many of the chronic anti-inflammatory effects of high density lipoprotein (HDL) are attributed to changes in cell adhesion molecules,
Autor:
David L. Huso, Clare Bao, Baktiar O. Karim, Ralph H. Hruban, Munekazu Yamakuchi, Joshua T. Mendell, Charles J. Lowenstein, Craig Lotterman
Publikováno v:
Proceedings of the National Academy of Sciences. 107:6334-6339
The pathway involving the tumor suppressor gene TP53 can regulate tumor angiogenesis by unclear mechanisms. Here we show that p53 regulates hypoxic signaling through the transcriptional regulation of microRNA-107 (miR-107). We found that miR-107 is a
Publikováno v:
The Journal of Experimental Medicine
The mitogen-activated protein kinase (MAPK) pathway plays a critical role in Toll-like receptor (TLR) signaling. MAPK phosphatase-1 (MKP-1) inhibits the MAPK pathway and decreases TLR signaling, but the regulation of MKP-1 is not completely understoo
Autor:
Charles J. Lowenstein, Nancy C. Kirkiles-Smith, Munekazu Yamakuchi, William M. Baldwin, Clare Bao, Scott J. Cameron, Jordan S. Pober, Marcella Ferlito, Barbara A. Wasowska, Karen Fox-Talbot
Publikováno v:
Proceedings of the National Academy of Sciences. 104:1301-1306
Although antibodies to HLA play a role in the pathogenesis of diseases processes such as rejection of transplanted organs, the precise mechanisms by which antibodies cause tissue injury are not completely understood. We hypothesized that antibodies t
Autor:
Carlos Zaragoza, Manuel Rodríguez-Puyol, Clare Bao, Charles J. Lowenstein, Marta Saura, Beatriz Herranz
Publikováno v:
Journal of Biological Chemistry. 281:30057-30062
Chronic activation of the acute phase response (APR) is associated with atherosclerosis. Elevated levels of interleukin-6, the major inducer of the APR, are associated with an increased risk of cardiovascular events. One of the clinical hallmarks of
Autor:
Elizaveta Padalko, Clare Bao, Kenji Matsushita, Karen Fox-Talbot, William M. Baldwin, Tomokazu Ohnishi, Henry Sun, Charles J. Lowenstein
Publikováno v:
Proceedings of the National Academy of Sciences. 101:11731-11736
Although peroxynitrite is harmful to the host, the beneficial effects of peroxynitrite are less well understood. We explored the role of peroxynitrite in the host immune response to Coxsackievirus infection. Peroxynitrite inhibits viral replicationin
Publikováno v:
Proceedings of the National Academy of Sciences. 100:7773-7778
Nitric oxide (NO) is an antiviral effector of the innate immune system. Viruses that can interfere with NO synthesis may be able to replicate more rapidly than viruses that cannot limit NO synthesis. We show that the adenovirus E1A protein inhibits N
Autor:
Marta Saura, Diego Rodríguez-Puyol, Wangsen Cao, Charles J. Lowenstein, Manuel Rodríguez-Puyol, Carlos Zaragoza, Clare Bao
Publikováno v:
Circulation Research. 91:806-813
Transforming growth factor-beta (TGF-beta) increases expression of endothelial nitric oxide synthase (eNOS), although the precise mechanism by which it does so is unclear. We report that Smad2, a transcription factor activated by TGF-beta, mediates T
Autor:
Qiuyu Zhu, Clare Bao, Sara Ture, Marcella Ferlito, Craig N Morrell, Munekazu Yamakuchi, Charles J Lowenstein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Endothelial cells maintain the integrity of the vasculature. In response to injury, endothelial cells undergo exocytosis, releasing various compounds into the blood stream by vesicle fusion with the plasma membrane. Endothelial exocytosis provokes in