Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Clare, Durrant"'
Autor:
Ella Hirani, Bo Shan, Erik Årstad, Imtiaz Khan, Edward G. Robins, Harry John Wadsworth, Wai-Fung Chau, Sajinder K. Luthra, Joanna Passmore, Yongjun Zhao, Veronique Morisson-Iveson, Sarah Walton, William Trigg, Paul A. Jones, Michelle Avory, Dennis O'shea, Clare Durrant, Rabia Ahmad, Dimitrios Mantzilas
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:2368-2372
A series of novel TSPO ligands based on the tetracyclic class of translocator protein (TSPO) ligands first described by Okubo et al. was synthesised and evaluated as potential positron emitting tomography (PET) ligands for imaging TPSO in vivo. Fluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394b1e289a06fbfe4bc81df52858121c
https://doi.org/10.1016/j.bmcl.2013.02.057
https://doi.org/10.1016/j.bmcl.2013.02.057
Autor:
Wai-Fung Chau, Dimitrios Mantzilas, Naghmeh Fouladi, Mikkel Thaning, Paul A. Jones, William Trigg, Veronique Morisson-Iveson, Ingvil Gausemel, Clare Durrant, Imtiaz Khan, Andrew Black, Joanna Passmore, Michelle Avory, Dennis O'shea, Harry John Wadsworth, Amanda Ewan, Duncan Wynn
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1308-1313
A series of tricyclic compounds have been synthesised and evaluated in vitro for affinity against Translocator protein 18 kDa (TSPO) and for preferred imaging properties. The most promising of the compounds were radiolabelled and evaluated in vivo to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9f7aae2c6ef9e829fccfa42f32630ad
https://doi.org/10.1016/j.bmcl.2011.12.084
https://doi.org/10.1016/j.bmcl.2011.12.084
Autor:
Andrew Black, Ingvil Gausemel, Clare Durrant, Inger Oulie, Alan Peter Clarke, Paul A. Jones, William Trigg, Dimitrios Mantzilas, Imtiaz Khan, Astri Rogstad, Wai-Fung Chau
Publikováno v:
Nuclear medicine and biology. 42(9)
Introduction The tricyclic indole compound, [ 18 F]GE-180 has been previously identified as a promising positron emission tomography (PET) imaging agent of the translocator protein (TSPO) with the potential to aid in the diagnosis, prognosis and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66507cf6dd0079bd9d9c291eec985b6b
https://pubmed.ncbi.nlm.nih.gov/26072270
https://pubmed.ncbi.nlm.nih.gov/26072270
Autor:
Harry John Wadsworth, Wai-Fung Chau, Dennis O'shea, Paul A. Jones, Veronique Morisson-Iveson, William Trigg, Michelle Avory, Clare Durrant, Andrew Black, Imtiaz Khan, Duncan Wynn, Joanna Passmore
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(18)
A series of novel ligands based on the diaryl anilide (DAA) class of translocator protein (TSPO) ligands was synthesised and evaluated as potential positron emitting tomography (PET) ligands for imaging TPSO in vivo. Fluorine-18 labelling of the mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7353187ad0694d2237a65696caf437
https://pubmed.ncbi.nlm.nih.gov/22902658
https://pubmed.ncbi.nlm.nih.gov/22902658
Autor:
Harry, Wadsworth, Paul A, Jones, Wai-Fung, Chau, Clare, Durrant, Naghmeh, Fouladi, Joanna, Passmore, Dennis, O'Shea, Duncan, Wynn, Veronique, Morisson-Iveson, Amanda, Ewan, Mikkel, Thaning, Dimitrios, Mantzilas, Ingvil, Gausemel, Imtiaz, Khan, Andrew, Black, Michelle, Avory, William, Trigg
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(3)
A series of tricyclic compounds have been synthesised and evaluated in vitro for affinity against Translocator protein 18 kDa (TSPO) and for preferred imaging properties. The most promising of the compounds were radiolabelled and evaluated in vivo to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1265dd2071e904eee4ac03f9e25dc25a
https://pubmed.ncbi.nlm.nih.gov/22244939
https://pubmed.ncbi.nlm.nih.gov/22244939
Autor:
Bard Indrevoll, Susan Hoppmann, Matthias Glaser, Peter Iveson, Antonios Danikas, Duncan Hiscock, Clare Durrant
Publikováno v:
Cancer Research. 72:353-353
Background: The assessment of HER2 expression in biopsies from primary lesions of breast cancer patients is a standard procedure to select patients for HER2-targeted therapies. However, in metastatic disease in which HER2 status can change, determina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07509a5dc5f7114fae94aae9df70fbd1
https://doi.org/10.1158/1538-7445.am2012-353
https://doi.org/10.1158/1538-7445.am2012-353