High genomic diversity of novel phages infecting the plant pathogen Ralstonia solanacearum, isolated in Mauritius and Reunion islands

Autor: Angélina Trotereau, Claudine Boyer, Isabelle Bornard, Max Jean Bernard Pécheur, Catherine Schouler, Clara Torres-Barceló

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract Bacterial wilt caused by the Ralstonia solanacearum species complex (RSSC) is among the most important plant diseases worldwide, severely affecting a high number of crops and ornamental plants in tropical regions. Only a limited number of ph

Externí odkaz: https://doaj.org/article/aa26fb08f7844a4ab562e7a9ff4c062f

Phage Therapy Faces Evolutionary Challenges

Autor: Clara Torres-Barceló

Publikováno v: Viruses, Vol 10, Iss 6, p 323 (2018)

Antibiotic resistance evolution in bacteria indicates that one of the challenges faced by phage therapy is that, sooner or later, bacteria will evolve resistance to phages. Evidently, this is the case of every known antimicrobial therapy, but here th

Externí odkaz: https://doaj.org/article/620bb919d9104422a3bfa92f7d97ae7c

Mitigation of evolved bacterial resistance to phage therapy

Autor: Clara Torres-Barceló, Paul E Turner, Angus Buckling

Publikováno v: Current opinion in virology. 53

The ease with which bacteria can evolve resistance to phages is a key consideration for development of phage therapy. Here, we review recent work on the different evolutionary and ecological approaches to mitigate the problem. The approaches are broa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61598836a34dffc72629c825b9a3a1b3
https://pubmed.ncbi.nlm.nih.gov/35180532

Transient negative effects of antibiotics on phages do not jeopardise the advantages of combination therapies

Autor: Michael E. Hochberg, Clara Torres-Barceló, James Gurney, Claire Gougat-Barbera, Marie Vasse

Publikováno v: FEMS Microbiology Ecology
FEMS Microbiology Ecology, Wiley-Blackwell, 2018, 94 (8), pp.fiy107. ⟨10.1093/femsec/fiy107⟩

International audience; Phages, the viruses of bacteria, have been proposed as antibacterial agents to complement or replace antibiotics due to the growing problem of resistance. In nature and in the clinic, antibiotics are ubiquitous and may affect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98262a61b73ddc4339c5cd1885dc7a7
https://doi.org/10.1093/femsec/fiy107

Size evolution in microorganisms masks trade-offs predicted by the growth rate hypothesis

Autor: Thierry Bouvier, Dominique Gravel, Isabelle Gounand, Corinne Bouvier, Franck Poly, Claire Gougat-Barbera, Marine Combe, Nicolas Mouquet, Tanguy Daufresne, Clara Torres-Barceló

Publikováno v: Proceedings of the Royal Society B: Biological Sciences
Proceedings of the Royal Society B: Biological Sciences, Royal Society, The, 2016, 283 (1845), 〈10.1098/rspb.2016.2272〉
Proceedings of the Royal Society B: Biological Sciences, Royal Society, The, 2016, 283 (1845), ⟨10.1098/rspb.2016.2272⟩

Adaptation to local resource availability depends on responses in growth rate and nutrient acquisition. The growth rate hypothesis (GRH) suggests that growing fast should impair competitive abilities for phosphorus and nitrogen due to high demand for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cb9af1affab15695ebb1c3bee7a3b3
https://www.zora.uzh.ch/id/eprint/133920/