Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Clara Türk"'
Autor:
Fubiao Shi, Flaviane de Fatima Silva, Dianxin Liu, Hari U. Patel, Jonathan Xu, Wei Zhang, Clara Türk, Marcus Krüger, Sheila Collins
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101753- (2023)
Objective: Norepinephrine stimulates the adipose tissue thermogenic program through a β-adrenergic receptor (βAR)–cyclic adenosine monophosphate (cAMP)–protein kinase A (PKA) signaling cascade. We discovered that a noncanonical activation of th
Externí odkaz:
https://doaj.org/article/c92f70da6a644433972fcbc963ffaba4
Autor:
Theresa Bock, Clara Türk, Sriram Aravamudhan, Lena Keufgens, Wilhelm Bloch, Dieu Hien Rozsivalova, Vanina Romanello, Leonardo Nogara, Bert Blaauw, Aleksandra Trifunovic, Thomas Braun, Marcus Krüger
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Mitochondria in skeletal muscle have distinct localization and properties through unclear mechanisms. Here, the authors use complexome profiling and immunoprecipitations to identify PERM1 as a MICOS-MIB complex interactor that also binds ankyrin B, s
Externí odkaz:
https://doaj.org/article/388735121d3e40b9adaa050527702242
Autor:
Sebastian Kallabis, Lena Abraham, Stefan Müller, Verena Dzialas, Clara Türk, Janica Lea Wiederstein, Theresa Bock, Hendrik Nolte, Leonardo Nogara, Bert Blaauw, Thomas Braun, Marcus Krüger
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract Background Skeletal muscles are composed of a heterogeneous collection of fiber types with different physiological adaption in response to a stimulus and disease-related conditions. Each fiber has a specific molecular expression of myosin he
Externí odkaz:
https://doaj.org/article/277cd04e3dab44c684355adea4b6995b
Autor:
Martina Baraldo, Alessia Geremia, Marco Pirazzini, Leonardo Nogara, Francesca Solagna, Clara Türk, Hendrik Nolte, Vanina Romanello, Aram Megighian, Simona Boncompagni, Marcus Kruger, Marco Sandri, Bert Blaauw
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 1, Pp 208-225 (2020)
Abstract Background Skeletal muscle is a plastic tissue that can adapt to different stimuli. It is well established that Mammalian Target of Rapamycin Complex 1 (mTORC1) signalling is a key modulator in mediating increases in skeletal muscle mass and
Externí odkaz:
https://doaj.org/article/5034fd17f0124217ab6feff1168397f9
Autor:
Wiebke A. Rehorst, Maximilian P. Thelen, Hendrik Nolte, Clara Türk, Sebahattin Cirak, Jonathan M. Peterson, G. William Wong, Brunhilde Wirth, Marcus Krüger, Dominic Winter, Min Jeong Kye
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-19 (2019)
Abstract Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder, which causes dysfunction/loss of lower motor neurons and muscle weakness as well as atrophy. While SMA is primarily considered as a motor neuron disease, recent data sugge
Externí odkaz:
https://doaj.org/article/3a45f28b932f4b949072050c3401599a
Autor:
Franziska Lang, Sriram Aravamudhan, Hendrik Nolte, Clara Türk, Soraya Hölper, Stefan Müller, Stefan Günther, Bert Blaauw, Thomas Braun, Marcus Krüger
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 7, Pp 881-896 (2017)
Loss of neuronal stimulation enhances protein breakdown and reduces protein synthesis, causing rapid loss of muscle mass. To elucidate the pathophysiological adaptations that occur in atrophying muscles, we used stable isotope labelling and mass spec
Externí odkaz:
https://doaj.org/article/d21884356e0f497c8ab97e2ecf126f94
Autor:
Franziska Koser, Mahmoud Abdellatif, Clara Türk, Anastasia J. Hobbach, Holger Reinecke, Marcus Krüger, Simon Sedej, Wolfgang Linke
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:16-17
Autor:
Franziska Koser, Anastasia J. Hobbach, Mahmoud Abdellatif, Viktoria Herbst, Clara Türk, Holger Reinecke, Marcus Krüger, Simon Sedej, Wolfgang A. Linke
Publikováno v:
Life sciences. 309
Despite the high prevalence of heart failure with preserved ejection fraction (HFpEF), the pathomechanisms remain elusive and specific therapy is lacking. Disease-causing factors include metabolic risk, notably obesity. However, proteomic changes in
Autor:
Vanina Romanello, Thomas Braun, Clara Türk, Bert Blaauw, Dieu Hien Rozsivalova, Lena Keufgens, Wilhelm Bloch, Marcus Krüger, Aleksandra Trifunovic, Leonardo Nogara, Theresa Bock, Sriram Aravamudhan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Skeletal muscle subsarcolemmal mitochondria (SSM) and intermyofibrillar mitochondria subpopulations have distinct metabolic activity and sensitivity, though the mechanisms that localize SSM to peripheral areas of muscle fibers are poorly understood.
Autor:
Clara Türk, Sarah Klapproth, Julian Dominik, Karsten Richter, Inaam A. Nakchbandi, Michael W. Hess, Markus Moser, Theresa Bock, Christoph A. Reichel, Kathrin Huck, Kristian Pfaller, Marcus Krüger, Thomas Bromberger
Publikováno v:
Journal of cell science. 134(22)
Osteoclasts form special integrin-mediated adhesion structures called sealing zones that enable them to adhere to and resorb bone. Sealing zones consist of densely packed podosomes tightly interconnected by actin fibers. Their formation requires the