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pro vyhledávání: '"Clara Siebert"'
Autor:
Stefan Masjosthusmann, Ellen Fritsche, Farina Bendt, Jenny Baumann, Clara Siebert, Ulrike Hübenthal
Publikováno v:
Chemosphere. 235:447-456
Arsenic exposure disturbs brain development in humans. Although developmental neurotoxicity (DNT) of arsenic has been studied in vivo and in vitro, its mode-of-action (MoA) is not completely understood. Here, we characterize the adverse neurodevelopm
Autor:
Ellen Fritsche, Jördis Klose, Ulrike Hübenthal, Jenny Baumann, René Deenen, Clara Siebert, Stefan Masjosthusmann, Daniel Becker, Katharina Dach, Karl Köhrer, Barbara Petzuch, Julia Tigges, Marta Barenys
Publikováno v:
Toxicology and applied pharmacology. 354
It is widely accepted that human brain development has unique features that cannot be represented by rodents. Obvious reasons are the evolutionary distance and divergent physiology. This might lead to false predictions when rodents are used for safet