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of 17
pro vyhledávání: '"Clara Si Hua Tan"'
Glucokinase activating mutation causing hypoglycaemia diagnosed late in adult who fasts for Ramadhan
Autor:
Wann Jia Loh, Lily Mae Dacay, Clara Si Hua Tan, Su Fen Ang, Fabian Yap, Su Chi Lim, Joan Khoo
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2021)
Activating mutation of glucokinase gene (GCK) causes resetting of insulin inhibition at a lower glucose threshold causing hyperinsulinaemic hypoglycaemia (GCK-HH). This is the first reported case who tolerated years of regular fasting during Ramadhan
Externí odkaz:
https://doaj.org/article/8cbf120d7b824e2baf3c19ffb0581fe7
Autor:
Clara Si Hua Tan MSc, Su Fen Ang PhD, Ester Yeoh MBBS, MRCP, M.Med, FAMS, FRCP, Bing Xing Goh MBBS, Wann Jia Loh MBBS, MRCP, M.Med, Cheuk Fan Shum MBBS, MRCSEd, M.Med (Surgery), FAMS, Molly May Ping Eng MB, BCh, BAO, MRCS, FRCSI, Allen Yan Lun Liu MBChB, MRCP, Lovynn Wan Ting Chan BSc, Li Xian Goh Dip, Tavintharan Subramaniam MBBS, MRCP, FRCP, FAM, Chee Fang Sum MBBS, FRCP, FACE, FAMS, Su Chi Lim MBBS, MRCP, FRCP, FAMS, PhD
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 10 (2022)
From our monogenic diabetes registry set-up at a secondary-care diabetes center, we identified a nontrivial subpopulation (~15%) of maturity-onset diabetes of the young (MODY) among people with young-onset diabetes. In this report, we describe the di
Externí odkaz:
https://doaj.org/article/63f22904ee5c4da2a56906cf9d7195b8
Glucokinase activating mutation causing hypoglycaemia diagnosed late in adult who fasts for Ramadhan
Autor:
Clara Si Hua Tan, Su Chi Lim, Joan Khoo, Fabian Yap, Su Fen Ang, Wann Jia Loh, Lily Mae Quevedo Dacay
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2021)
Endocrinology, Diabetes & Metabolism Case Reports
Endocrinology, Diabetes & Metabolism Case Reports
Summary Activating mutation of glucokinase gene (GCK) causes resetting of insulin inhibition at a lower glucose threshold causing hyperinsulinaemic hypoglycaemia (GCK-HH). This is the first reported case who tolerated years of regular fasting during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef45b4fe8c7888c2f48e35693a307c8
https://edm.bioscientifica.com/view/journals/edm/2021/1/EDM21-0043.xml
https://edm.bioscientifica.com/view/journals/edm/2021/1/EDM21-0043.xml
Autor:
Su Chi Lim, Bhuvaneswari Pandian, Su Fen Ang, Clara Si Hua Tan, Anton Cheng, Chee Fang Sum, Mei Chung Moh, Wanxin Lai, Boon Khim Lim, Tavintharan Subramaniam, Chun Hai Tan
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 8 (2020)
Journal of Investigative Medicine High Impact Case Reports
Journal of Investigative Medicine High Impact Case Reports
A 43-year-old man, with severe obesity (43 kg/m2) and diabetes (presumed as type 2 diabetes [T2D]), underwent vertical sleeve gastrectomy in 2009 and Roux-en-Y gastric bypass in 2013. Recently, whole exome sequencing (conducted to search for monogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e070cc2327241f37d22405dce5cedb1
https://doaj.org/article/ab6c1563b6b3490a8c5b11d54e0be459
https://doaj.org/article/ab6c1563b6b3490a8c5b11d54e0be459
Publikováno v:
Diabetes. 69
Introduction: Monogenic diabetes (also known as maturity-onset diabetes of the young or MODY) is a rare genetic disorder with an undetermined prevalence in Singapore. The NHG-KTPH Monogenic Diabetes Registry was set up in mid-2017 to capture longitud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed8cf4b3d409263193ad3733f6580936
https://doi.org/10.2337/db20-1661-p
https://doi.org/10.2337/db20-1661-p
Autor:
Tavintharan Subramanium, Su Chi Lim, Lovynn W.T. Chan, Chee Fang Sum, Winston Y.C. Kon, Su Fen Ang, Li Xian Goh, Clara Si Hua Tan, Joyce Xia Lian
Publikováno v:
Diabetes research and clinical practice. 168
Monogenic diabetes (also known as maturity-onset diabetes of the young or MODY) affects a subset of individuals with young-onset diabetes. We report our diagnostic work-up experience for such individuals.Serving as a regional secondary-care diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236d4e41903c9eba58a6b2ec8fb2370f
https://pubmed.ncbi.nlm.nih.gov/32858097
https://pubmed.ncbi.nlm.nih.gov/32858097
Publikováno v:
Eur J Hum Genet
Maturity-onset diabetes of the young (MODY) is a genetically and clinically heterogeneous group of disorders characterised by early onset, lean, non-autoimmunity mediated, non-insulin-dependent diabetes often with autosomal-dominant inheritance and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271341c42543ae4082dfee7418bd528e
https://europepmc.org/articles/PMC7080716/
https://europepmc.org/articles/PMC7080716/
Autor:
Su Fen Ang, Tavintharan Subramaniam, Clara Si Hua Tan, Pek Yee Kwan, Angela Mei Chung Moh, Keven Ang, Su Chi Lim, Jiexun Wang, Chee Fang Sum, Wern Ee Tang, Simon Biing Ming Lee
Publikováno v:
Diabetes research and clinical practice. 157
Increased adiposity confers elevated risk for diabetic kidney disease (DKD) progression in type 2 diabetes mellitus (T2DM). This 3-year prospective study examined whether worsening of metabolic control e.g. development of uncontrolled diabetes mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6be6e3e66d61127a92636cfeece011
https://pubmed.ncbi.nlm.nih.gov/31401149
https://pubmed.ncbi.nlm.nih.gov/31401149
Publikováno v:
Eur J Hum Genet
A 22-year-old man was referred for continuation of diabetes mellitus treatment. He was first diagnosed with diabetes mellitus 2 months after birth, when he failed to thrive and showed symptoms of diabetic ketoacidosis. There was no family history of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ee3b4c73c2ffb8229b71e83f09b95a
https://pubmed.ncbi.nlm.nih.gov/30890782
https://pubmed.ncbi.nlm.nih.gov/30890782
Autor:
Babitha Jeevith, Jamaliah Bte Rahim, Winston Y.C. Kon, Su Fen Ang, Jessie C.W. Fong, Chee Fang Sum, Wern Ee Tang, Keven Ang, Ling Wang, Tavintharan Subramanium, Joyce Xia Lian, Simon Biing Ming Lee, Rajkumar Dorajoo, Su Chi Lim, Jianjun Liu, Clara Si Hua Tan
Publikováno v:
Journal of diabetes and its complications. 33(1)
Young-onset T2D (YT2D) is associated with a more fulminant course and greater propensity for diabetic complications. The association of PAX4 R192H (rs2233580) variation with YT2D was inconsistent partly because of its Asian-specificity and under-repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b2063d76a6be87457c36beb800c37e
https://pubmed.ncbi.nlm.nih.gov/30528630
https://pubmed.ncbi.nlm.nih.gov/30528630