Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Clara S. Tang"'
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Amyloid-beta (Aβ) and tau protein are both involved in the pathogenesis of Alzheimer’s disease. Aβ produces synaptic deficits in wild-type mice that are not seen in Mapt −/− mice, suggesting that tau protein is required for these eff
Externí odkaz:
https://doaj.org/article/2cf996095fe74836876c8b460971070e
Autor:
Yuen-Kwun Wong, Chloe Y. Y. Cheung, Clara S. Tang, JoJo S. H. Hai, Chi-Ho Lee, Kui-Kai Lau, Ka-Wing Au, Bernard M. Y. Cheung, Pak-Chung Sham, Aimin Xu, Karen S. L. Lam, Hung-Fat Tse
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background High-sensitivity troponin I (hs-Tnl) and B-type natriuretic peptide (BNP) are promising prognostic markers for coronary artery disease (CAD). This prospective cohort study investigated whether a combination of these cardiac biomar
Externí odkaz:
https://doaj.org/article/fc6a8049ae44438aabf29871c72e76ba
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6 (2021)
To survive, animals have to quickly modify their behaviour when the reward changes. The internal representations responsible for this are updated through synaptic weight changes, mediated by certain neuromodulators conveying feedback from the environ
Externí odkaz:
https://doaj.org/article/ca14b24a657a430da9587a5667584597
Autor:
Youling Guo, Brian Tomlinson, Tanya Chu, Yu Jing Fang, Hongsheng Gui, Clara S. Tang, Benjamin H. Yip, Stacey S. Cherny, Yoon-Mi Hur, Pak Chung Sham, Tai Hing Lam, Neil G. Thomas
Publikováno v:
PLoS ONE, Vol 7, Iss 6 (2012)
Externí odkaz:
https://doaj.org/article/2cb667cf2a164c9d84cd414973955dce
Autor:
Santhi K. Ganesh, Yan Zhang, Karen Sl Lam, Haiyi Yu, Yujun Dong, Yong Huo, Min-Lee Yang, Wei Zhou, He Zhang, Cristen J. Willer, Hung Fat Tse, Y. Eugene Chen, Chloe Y Y Cheung, Wei Gao, Pak C. Sham, Clara S. Tang, Jia Jia, Ming Xu, Yi Fu, Pengfei Sun
Publikováno v:
Hum Mol Genet
Genomic discovery efforts for hematological traits have been successfully conducted through genome-wide association study on samples of predominantly European ancestry. We sought to conduct unbiased genetic discovery for coding variants that influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5ee6abaf1579a2edeebc5126793e74
https://doi.org/10.1093/hmg/ddab062
https://doi.org/10.1093/hmg/ddab062
Autor:
Mullin H.C. Yu, Brian H.Y. Chung, Paul K.H. Tam, Yu-Lung Lau, Christopher C.Y. Mak, Patrick Ho Yu Chung, Jasmine L.F. Fung, Mandy H.Y. Tsang, Clara S. Tang, Mianne Lee, Jeffrey Fong Ting Chau, So Lun Lee, Wanling Yang, Godfrey Chi-Fung Chan, Kit San Yeung
Publikováno v:
Journal of Human Genetics. 66:637-641
The use of exome and genome sequencing has increased rapidly nowadays. After primary analysis, further analysis can be performed to identify secondary findings that offer medical benefit for patient care. Multiple studies have been performed to evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5773c662e5e4bfb0d69ee50687f50bb9
https://doi.org/10.1038/s10038-020-00875-w
https://doi.org/10.1038/s10038-020-00875-w
Mendelian Randomization Focused Analysis of Vitamin D on the Secondary Prevention of Ischemic Stroke
Autor:
YK Wong, Chloe Y Y Cheung, Clara S. Tang, Aimin Xu, Kar Keung Cheng, Pak C. Sham, C. Mary Schooling, Karen Siu-Ling Lam, Tai Hing Lam, Chaoqiang Jiang, G. Neil Thomas, Ka-Wing Au, Shiu Lun Au Yeung, Hung-Fat Tse, Jo-Jo Hai, Jie V. Zhao, Yap-Hang Chan
Publikováno v:
Stroke. 52(12)
Background and Purpose: Experimental studies showed vitamin D (Vit-D) could promote vascular regeneration and repair. Prior randomized studies had focused mainly on primary prevention. Whether Vit-D protects against ischemic stroke and myocardial inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6928d2b67cd2f9f70c8478d1bff5b73e
https://pubmed.ncbi.nlm.nih.gov/34565175
https://pubmed.ncbi.nlm.nih.gov/34565175
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9659, p 9659 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 9659, p 9659 (2021)
The development of the enteric nervous system (ENS) is highly modulated by the synchronized interaction between the enteric neural crest cells (ENCCs) and the neural stem cell niche comprising the gut microenvironment. Genetic defects dysregulating t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03362f93faff91914936b83c7c93a68
https://pubmed.ncbi.nlm.nih.gov/34575824
https://pubmed.ncbi.nlm.nih.gov/34575824
Autor:
Alice S. Brooks, Robert van der Helm, Bianca M. de Graaf, Erwin Brosens, Conny J.H.M. Meeussen, Laura E. Kuil, Robert M.W. Hofstra, Thuy Linh Le, Anwarul Karim, Annelies de Klein, Rene M. H. Wijnen, Cornelius E. J. Sloots, Paul K.H. Tam, Maria M. Alves, Yolande van Bever, Clara S. Tang, Maria-Mercè Garcia-Barceló, Jeanne Amiel, Jonathan D. Windster, Katherine C. MacKenzie, Dick Tibboel, Stanislas Lyonnet
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009698 (2021)
PLoS Genetics, 17(8):1009698. Public Library of Science
PLoS Genetics
PLoS Genetics, 17(8):1009698. Public Library of Science
PLoS Genetics
Hirschsprung disease (HSCR) is a complex genetic disease characterized by absence of ganglia in the intestine. HSCR etiology can be explained by a unique combination of genetic alterations: rare coding variants, predisposing haplotypes and Copy Numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffd6b90755de1ab4d3626dcb53e08d4
http://www.scopus.com/inward/record.url?scp=85114296624&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85114296624&partnerID=8YFLogxK
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Frontiers in Pediatrics
Frontiers in Pediatrics
Hirschsprung disease (HSCR) is the leading cause of neonatal functional intestinal obstruction. It is a rare congenital disease with an incidence of one in 3,500–5,000 live births. HSCR is characterized by the absence of enteric ganglia in the dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe77e4f1efbedb0be44f6a4ac486848
https://www.frontiersin.org/articles/10.3389/fped.2021.638093/full
https://www.frontiersin.org/articles/10.3389/fped.2021.638093/full