Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Clara S. Genther"'
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 31:612-645
This report summarizes the results of a longitudinal study of the characteristics of untreated infections with trophozoites and sporozoites of the M, B, and Ro strains of P. cynomolgi. The pre-initial-peak phases of infections with trophozoites of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a085228ab5a62b7b5b1fc9b4e69c8f9
https://doi.org/10.4269/ajtmh.1982.31.612
https://doi.org/10.4269/ajtmh.1982.31.612
Publikováno v:
Journal of Medicinal Chemistry. 28:1910-1916
Sets of 5-(substituted benzyl)-2,4-diaminopyrimidines and 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-substituted phenyl)-s-triazines as well as several other antifolates were tested as inhibitors of Escherichia coli dihydrofolate reductase and E. coli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5a86c8d426ec82302217d5e1ab31bf
https://doi.org/10.1021/jm00150a026
https://doi.org/10.1021/jm00150a026
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 31:646-665
Quinine, quinacrine, chloroquine, amodiaquine, chlorguanide, and pyrimethamine, administered at fractions of their maximum tolerated doses, regularly cured established infections with trophozoites of the M strain of Plasmodium cynomolgi. Chloroquine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea7c6705ce0a86742f87983b96d62985
https://doi.org/10.4269/ajtmh.1982.31.646
https://doi.org/10.4269/ajtmh.1982.31.646
Autor:
Ellen Wagner, John K. Baker, Michael A. Pleiss, Dilip M. Nene, Clara S. Genther, J. A. Roesener, Stanley R. Milstein, James J. Schmidt, Kishorkant J. Shah, Eugene A. Coats
Publikováno v:
Journal of Medicinal Chemistry. 25:57-63
Studies on dehydrogenase enzyme inhibition have been extended with the design, synthesis, and correlation analysis of 7-[(substituted-benzyl)oxy]-, 7-[(substituted-phenethyl)oxy]-, and 7([substituted-phenoxy)ethoxy]-4-hydroxyquinoline-3-carboxylic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959f2e2023cb84551f94188b3b2b3233
https://doi.org/10.1021/jm00343a011
https://doi.org/10.1021/jm00343a011
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 31:666-680
This report summarizes the results of experimental studies that underpinned evaluation of primaquine in human volunteers inoculated with sporozoites of the Chesson strain of Plasmodium vivax and current uses of this 8-aminoquinoline for curative and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716b9100d24cfc51487baae38fc5d206
https://doi.org/10.4269/ajtmh.1982.31.666
https://doi.org/10.4269/ajtmh.1982.31.666
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 31:681-698
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::949cdd49adc630c18747d155fbc548bb
https://doi.org/10.4269/ajtmh.1982.31.681
https://doi.org/10.4269/ajtmh.1982.31.681
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 58:159-163
1. 1) This report deals with preliminary efforts to localize the site(s) of development of the pre-erythrocytic forms of P. cynomolgi by use of tissue implantation techniques. Twelve infant rhesus monkeys killed 4, 5, 6, and 7 days after inoculation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bef290cb47e357413fb17655402f2b7
https://doi.org/10.1016/0035-9203(64)90005-7
https://doi.org/10.1016/0035-9203(64)90005-7
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 10:679-688
Summary On May 8, 1960, one of the staff of the Parasitology Section of this Institute developed a febrile illness subsequently diagnosed as malaria. Paroxysms of tertian periodicity were produced by a parasite morphologically indistinguishable from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb51df979b7a07f3ca68467fd2bda043
https://doi.org/10.4269/ajtmh.1961.10.679
https://doi.org/10.4269/ajtmh.1961.10.679
Autor:
Clara S. Genther, Carl C. Smith
Publikováno v:
Journal of medicinal chemistry. 20(2)
As part of the search for new antimalarial drugs, a screening program was developed using sensitive and chlorguanide triazine (CGT, cycloguanil) resistant strains of the folate-requiring bacteria, Streptococcus faecium durans, Lactobacillus casei, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93650658de51f50c52018285e12a49af
https://pubmed.ncbi.nlm.nih.gov/137981
https://pubmed.ncbi.nlm.nih.gov/137981
Publikováno v:
Chemischer Informationsdienst. 17
Sets of 5-(substituted benzyl)-2,4-diaminopyrimidines and 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-substituted phenyl)-s-triazines as well as several other antifolates were tested as inhibitors of Escherichia coli dihydrofolate reductase and E. coli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13629c6daba98ca8a1552c3f3f975427
https://doi.org/10.1002/chin.198614227
https://doi.org/10.1002/chin.198614227