Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Clara Pampillón"'
Autor:
Nigel J. Sweeney, Matthias Tacke, Catherine M. Dowling, R. William G. Watson, Iduna Fichtner, Clara Pampillón, Sandra Cuffe, James Claffey, Katja Strohfeldt
Publikováno v:
Letters in Drug Design & Discovery. 5:141-144
Chemotherapeutic options for androgen-independent prostate cancer are extremely limited with minimum survival advantage. The benzyl-substituted unbridged titanocene bis-[(p-methoxybenzyl) cyclopentadienyl] titanium(IV) dichloride (Titanocene Y) was t
Publikováno v:
Journal of Organometallic Chemistry. 693:526-536
From the reaction of 6(2-methoxy-phenyl)fulvene ( 1a ), 6(3-methoxy-phenyl)fulvene ( 1b ), 6(3,4-dimethoxy-phenyl)fulvene ( 1c ) and 6(3,4,5-trimethoxy-phenyl)fulvene ( 1d ) with LiBEt 3 H, lithiated cyclopentadienide intermediates 2a – d were synt
Autor:
Amanda O'Neill, Iduna Fichtner, Nigel J. Sweeney, John H. Bannon, Matthias Tacke, Katja Strohfeldt, R.W.G. Watson, Margaret M. Mc Gee, Clara Pampillón
Publikováno v:
British Journal of Cancer
Titanocene compounds are a novel series of agents that exhibit cytotoxic effects in a variety of human cancer cells in vitro and in vivo. In this study, the antiproliferative activity of two titanocenes (Titanocenes X and Y) was evaluated in human ep
Publikováno v:
Zeitschrift für anorganische und allgemeine Chemie. 633:1695-1700
From the carbolithiation of 6-morpholino fulvene (3a) and different ortho-lithiated heterocycles (furan, thiophene and N-methylpyrrole), the corresponding lithium cyclopentadienide intermediate (4a–c) was formed. These three lithiated intermediates
Publikováno v:
Transition Metal Chemistry. 32:971-980
Substituted titanocenes like ansa-titanocenes, diarylmethyl-substituted and benzyl-substituted titanocenes, are known for their cytotoxic potential and they can be synthesised using 6-arylfulvenes. Nevertheless, in the case of using 6-(4-morpholin-4y
Autor:
Matthias Tacke, Nigel J. Sweeney, Katja Strohfeldt, Ying Lou, Ina Dix, James Claffey, Helge Müller-Bunz, Clara Pampillón
Publikováno v:
Zeitschrift für Kristallographie. 222:376-382
The syntheses and crystal structures of a series of 6-(substituted-phenyl) fulvenes are reported. In three instances the molecular structures determined by X-Ray crystallography were compared to the results of DFT calculations. In these cases only mi
Publikováno v:
Investigational New Drugs. 25:425-433
From the carbolithiation of 6-N,N-dimethylamino fulvene (3a) and different lithiated N-heterocyclic compounds (N,N-dimethylaminomethylpyrrole, 1-methylimidazole and 2,4-[bis(N',N'-dimethylaminomethyl)]-N-methyl pyrrole), the corresponding lithium cyc
Publikováno v:
Journal of Organometallic Chemistry. 692:2153-2159
Publikováno v:
Transition Metal Chemistry. 32:434-441
From the carbolithiation of 6-N,N-dimethylamino fulvene (3a) and different ortho-lithiated indole derivatives (5-methoxy-N-methylindole, N-methylindole and N,N-dimethylaminomethylindole), the corresponding lithium cyclopentadienide intermediate (4a
Publikováno v:
Organometallics. 26:2501-2506