Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Clara Ortega-de San Luis"'
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112999- (2023)
Summary: Long-term memories are stored as configurations of neuronal ensembles, termed engrams. Although investigation of engram cell properties and functionality in memory recall has been extensive, less is known about how engram cells are affected
Externí odkaz:
https://doaj.org/article/326d975891ee4b888bd1c0371f1a5ef2
Autor:
Maria I. Alvarez-Vergara, Alicia E. Rosales-Nieves, Rosana March-Diaz, Guiomar Rodriguez-Perinan, Nieves Lara-Ureña, Clara Ortega-de San Luis, Manuel A. Sanchez-Garcia, Miguel Martin-Bornez, Pedro Gómez-Gálvez, Pablo Vicente-Munuera, Beatriz Fernandez-Gomez, Miguel A. Marchena, Andrea S. Bullones-Bolanos, Jose C. Davila, Rocio Gonzalez-Martinez, Jose L. Trillo-Contreras, Ana C. Sanchez-Hidalgo, Raquel del Toro, Francisco G. Scholl, Eloisa Herrera, Martin Trepel, Jakob Körbelin, Luis M. Escudero, Javier Villadiego, Miriam Echevarria, Fernando de Castro, Antonia Gutierrez, Alberto Rabano, Javier Vitorica, Alberto Pascual
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Aß are extracellular deposits relevant in Alzheimer’s disease (AD). This study shows that Aß plaques are hubs of endothelial disassembly that induce non-productive angiogenesis. This process is aided by the microglia and unchained by reduced pres
Externí odkaz:
https://doaj.org/article/65297e3308ba45ef8cbc879a7f19dfe0
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 5 (2018)
Amnesia – the loss of memory function – is often the earliest and most persistent symptom of dementia. It occurs as a consequence of a variety of diseases and injuries. These include neurodegenerative, neurological or immune disorders, drug abuse
Externí odkaz:
https://doaj.org/article/3eb63c15dca648babadecffa7e9891ae
Autor:
Adrian Viehweger, Almudena Gerpe, Manuel A. Sanchez-Garcia, Maria V. Sanchez-Mico, Alberto Pascual, Angela Gomez-Arboledas, José López-Barneo, Jose Carlos Davila, Javier Vitorica, Alicia E. Rosales-Nieves, Marisa Vizuete, Victoria Navarro, Edurne Berra, Antonio Heras-Garvin, Nieves Lara-Ureña, Rosana March-Díaz, Carmen Romero-Molina, Cristina Forja, Elisabeth Sanchez-Mejias, Antonia Gutierrez, Maria I. Alvarez-Vergara, Clara Ortega-de San Luis, Tammie Bishop, Emma J. Hodson, Alberto Serrano-Pozo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Genetic Alzheimer’s disease (AD) risk factors associate with reduced defensive amyloid β plaque-associated microglia (AβAM), but the contribution of modifiable AD risk factors to microglial dysfunction is unknown. In AD mouse models, we observe c
Autor:
Sarah D. Power, Erika Stewart, Louisa G. Zielke, Eric Patrick Byrne, Clara Ortega-de San Luis, Lydia Lynch, Tomás J. Ryan
Infantile amnesia is possibly the most ubiquitous form of memory loss in mammals. Despite its widespread relevance, little is known about the biological conditions for infantile amnesia to occur and its effect on the engram cells that encode a memory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45d5a01e65e0f2e8df303d45105b6755
https://doi.org/10.1101/2022.04.24.488172
https://doi.org/10.1101/2022.04.24.488172
Autor:
Tomás Ryan, Clara Ortega-de San Luis
Publikováno v:
The Journal of biological chemistry. 298(5)
Memory, defined as the storage and use of learned information in the brain, is necessary to modulate behavior and critical for animals to adapt to their environments and survive. Despite being a cornerstone of brain function, questions surrounding th
Autor:
Júlio César Borges, Laura Rodríguez de la Fuente, Clara Ortega-de San Luis, Josimar O. Eloy, Mariza Aires Fernandes, Marlus Chorilli, Marcela Tavares Luiz, Maria Jose Santos-Martinez, Juliana Maldonado Marchetti, Sergio Luiz Ramos Junior
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Universidade de São Paulo (USP)
instacron:USP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2021-06-25T11:06:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-20 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9198d136abf9834b0d4a990721b62d52
Autor:
José Luis Trillo-Contreras, Pedro Gómez-Gálvez, Luis M. Escudero, Nieves Lara-Ureña, Andrea S. Bullones-Bolanos, Javier Vitorica, Miriam Echevarría, Rosana March-Díaz, Miguel Marchena, Jose Carlos Davila, Ana C. Sanchez-Hidalgo, Eloisa Herrera, Fernando de Castro, Jakob Körbelin, Antonia Gutierrez, Rocio González-Martínez, Alicia E. Rosales-Nieves, Raquel del Toro, Clara Ortega-de San Luis, Maria I. Alvarez-Vergara, Alberto Pascual, Pablo Vicente-Munuera, Manuel A. Sanchez-Garcia, Guiomar Rodriguez-Perinan, Martin Trepel, Francisco G. Scholl, Alberto Rábano, Javier Villadiego, Miguel Martin-Bornez, Beatriz Fernández-Gómez
Publikováno v:
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
The human Alzheimer’s disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature is reduced around Aß plaques. Here we demonstrate that angiogenesis is started near Aß plaques in both AD mouse models and hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa049ed47a103e3d3ff4480d727c21b5
Publikováno v:
Current opinion in neurobiology. 67
Understanding memory requires an explanation for how information can be stored in the brain in a stable state. The change in the brain that accounts for a given memory is referred to as an engram. In recent years, the term engram has been operational
Autor:
Adrian Viehweger, Angela Gomez-Arboledas, Edurne Berra, Cristina Forja, Nieves Lara-Ureña, Alicia E. Rosales-Nieves, Rosana March-Díaz, Maria V. Sanchez-Mico, Alberto Serrano-Pozo, Marisa Vizuete, Victoria Navarro, Alberto Pascual, José López-Barneo, Elisabeth Sanchez-Mejias, Javier Vitorica, Carmen Romero-Molina, Jose Carlos Davila, Antonio Heras-Garvin, Antonia Gutierrez, Maria I. Alvarez-Vergara, Clara Ortega-de San Luis
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Microglial cells are key contributors to Alzheimer’s disease (AD), constituting the first cellular line against Aß plaques. Local hypoxia and hypoperfusion, which are typically present in peripheral inflammatory foci, are also common in the AD bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b272ee8cde54d342aee706afb765da9a
http://hdl.handle.net/10261/272386
http://hdl.handle.net/10261/272386