Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Clara Moon"'
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21627 (2011)
Non-productive antigen receptor genes with frame shifts generated during the assembly of these genes are found in many mature lymphocytes. Transcripts from these genes have premature termination codons (PTCs) and could encode truncated proteins if th
Externí odkaz:
https://doaj.org/article/e2ff772871d342bf9ea8f042e8b4cf46
Autor:
Clara Moon, J. Rafael Montenegro-Burke, Xavier Domingo-Almenara, Lars Eckmann, Dennis W. Wolan, Seiya Kitamura, Bernard P. Kok, Carlos Guijas, Enrique Saez, Andrea Galmozzi, Gary Siuzdak
Publikováno v:
Sci Signal
Untargeted metabolomics of disease-associated intestinal microbiota can detect quantitative changes in metabolite profiles and complement other methodologies to reveal the full effect of intestinal dysbiosis. Here, we used the T cell transfer mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726b45bfe9d7ba6629fd076147508f59
https://doi.org/10.1126/scisignal.abf6584
https://doi.org/10.1126/scisignal.abf6584
Metaproteomics can greatly assist established high-throughput sequencing methodologies to provide systems biological insights into the alterations of microbial protein functionalities correlated with disease-associated dysbiosis of the intestinal mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37dda2cb1d8e66937dfd97ac05bfea40
https://europepmc.org/articles/PMC5921860/
https://europepmc.org/articles/PMC5921860/
Autor:
Charles S. Craik, Emily J. Roncase, Clara Moon, Sandip Chatterjee, Dennis W. Wolan, Gonzalo E. González-Páez, Anthony J. O’Donoghue
Publikováno v:
ACS chemical biology, vol 12, iss 6
Cysteine proteases are among the most abundant hydrolytic enzymes produced by bacteria, and this diverse family of proteins have significant biological roles in bacterial viability and environmental interactions. Members of the clostripain-like (C11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26b49a6a6484cc5cd690aae2f644b5f
https://europepmc.org/articles/PMC5575927/
https://europepmc.org/articles/PMC5575927/
Publikováno v:
Journal of proteome research. 16(2)
Tandem mass spectrometry based shotgun proteomics of distal gut microbiomes is exceedingly difficult due to the inherent complexity and taxonomic diversity of the samples. We introduce two new methodologies to improve metaproteomic studies of microbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ba5c0e4604a5c3a2f2d6af6cde58e2
https://pubmed.ncbi.nlm.nih.gov/28052195
https://pubmed.ncbi.nlm.nih.gov/28052195
Publikováno v:
Mucosal immunology
There is significant interest in the use of primary intestinal epithelial cells in monolayer culture to model intestinal biology. However, it has proven to be challenging to create functional, differentiated monolayers using current culture methods,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59631865507ec7d817cae2fa3426615a
https://doi.org/10.1038/mi.2013.98
https://doi.org/10.1038/mi.2013.98
Publikováno v:
Current Protocols in Pharmacology. :e54
Human intestinal organoids have enabled performance of functional epithelial studies and modeling of human diseases of the intestine. This unit describes 1) a method to isolate and culture crypts from human intestinal tissue, 2) use of combinatorial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce4f32befe85711a6ddb3f1dd1b915b
https://doi.org/10.1002/cpph.54
https://doi.org/10.1002/cpph.54
Autor:
Sun-Sang J. Sung, Masako Kohyama, Wumesh Kc, Loralyn A. Benoit, Wataru Ise, Theresa L. Murphy, Thaddeus S. Stappenbeck, Kai Hildner, Drew G. Michael, Paul A. Klekotka, Michael J. Holtzman, Brian T. Edelson, Clara Moon, Richard Juang, Deepta Bhattacharya, Kenneth M. Murphy, Jörn C. Albring
Publikováno v:
The Journal of Experimental Medicine
Although CD103-expressing dendritic cells (DCs) are widely present in nonlymphoid tissues, the transcription factors controlling their development and their relationship to other DC subsets remain unclear. Mice lacking the transcription factor Batf3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c8fb5631dfc8e8c08f214c9e295b29
https://doi.org/10.1084/jem.20091627
https://doi.org/10.1084/jem.20091627
Publikováno v:
PROTEOMICS. 18:1870031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49efd845c9ce42c578c22d2c677f46f6
https://doi.org/10.1002/pmic.201870031
https://doi.org/10.1002/pmic.201870031
Autor:
Clara, Moon, Megan T, Baldridge, Meghan A, Wallace, Carey-Ann, D, Burnham, Herbert W, Virgin, Thaddeus S, Stappenbeck
Publikováno v:
Nature
Microbially driven dichotomous faecal immunoglobulin-A levels in wild-type mice within the same facility mimic the effects of chromosomal mutations, indicating that phenotypic comparisons between mice must take into account the non-chromosomal heredi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755ec9cda2839651295dbc3a50958929
https://pubmed.ncbi.nlm.nih.gov/25686606
https://pubmed.ncbi.nlm.nih.gov/25686606