Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Clara I Linares"'
Autor:
Sandra González-Rubio, Clara I Linares, Patricia Aguilar-Melero, Manuel Rodríguez-Perálvarez, José L Montero-Álvarez, Manuel de la Mata, Gustavo Ferrín
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160525 (2016)
The harmful effects of bile acid accumulation occurring during cholestatic liver diseases have been associated with oxidative stress increase and endothelial nitric oxide synthase (NOS-3) expression decrease in liver cells. We have previously reporte
Externí odkaz:
https://doaj.org/article/687823b330fb4a06aabd224c01908286
Autor:
Gustavo Ferrín, Manuel Rodríguez-Perálvarez, Patricia Aguilar-Melero, Isidora Ranchal, Camilo Llamoza, Clara I Linares, Sandra González-Rubio, Jordi Muntané, Javier Briceño, Pedro López-Cillero, José Luis Montero-Álvarez, Manuel de la Mata
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118527 (2015)
Hepatocellular carcinoma (HCC) is one of the most common and lethal cancers in the world, with limited options for treatment unless timely diagnosed. Chronic hepatitis C virus (HCV) infection and persistent heavy alcohol consumption are independent r
Externí odkaz:
https://doaj.org/article/b0c9b72c2ab84d658a9330eb3c3dcfa5
Autor:
Rosario Medina-Medina, Eva Iglesias-Flores, Jose M. Benítez, Sandra Marín-Pedrosa, Isabel Salgueiro-Rodríguez, Clara I. Linares, Sandra González-Rubio, Pilar Soto-Escribano, Beatriz Gros, Manuel L. Rodríguez-Perálvarez, José L. Cabriada, María Chaparro, Javier P. Gisbert, Eduardo Chicano-Gálvez, Ignacio Ortea, Gustavo Ferrín, Valle García-Sánchez, Patricia Aguilar-Melero
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8695 (2023)
Therapy with anti-tumor necrosis factor (TNF) has dramatically changed the natural history of Crohn’s disease (CD). However, these drugs are not without adverse events, and up to 40% of patients could lose efficacy in the long term. We aimed to ide
Externí odkaz:
https://doaj.org/article/fc826a181fd145d4b5fd4b73a2930031
Autor:
María L. Espejo-Cruz, Sandra González-Rubio, Juan J. Espejo, Javier M. Zamora-Olaya, Rafael M. Alejandre-Altamirano, María Prieto-Torre, Clara I. Linares, Marta Guerrero-Misas, Pilar Barrera-Baena, Antonio Poyato-González, Marina Sánchez-Frías, María D. Ayllón, Manuel L. Rodríguez-Perálvarez, Manuel de la Mata, Gustavo Ferrín
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2558 (2023)
Circulating tumor cells (CTCs), and particularly circulating cancer stem cells (cCSC), are prognostic biomarkers for different malignancies and may be detected using liquid biopsies. The ex vivo culture of cCSCs would provide valuable information reg
Externí odkaz:
https://doaj.org/article/19dfebf2a79144da8fa08b06e64e5267
Autor:
Manuel Rodríguez-Perálvarez, Javier Zamora, Gema Garcia-Jurado, Marina E. Sánchez-Frías, María Lola Espejo-Cruz, Manuel de la Mata, Ruben Ciria, Clara I. Linares, Víctor Amado, Sandra González-Rubio, Gustavo Ferrín, Rafael Alejandre, José Luis Montero
Publikováno v:
Cancers
Volume 13
Issue 10
Cancers, Vol 13, Iss 2476, p 2476 (2021)
Volume 13
Issue 10
Cancers, Vol 13, Iss 2476, p 2476 (2021)
Background: In patients with hepatocellular carcinoma (HCC), a complete clearance of circulating tumor cells (CTCs) early after liver transplantation (LT) or surgical resection (LR) could prevent tumor recurrence. Methods: prospective pilot study inc
Autor:
Manuel de la Mata, Carmen Herencia, Clara I. Linares, Álvaro Naranjo, Isidora Ranchal, Patricia Aguilar-Melero, Amparo Valverde, Sandra González-Rubio, Ruben Ciria, Javier Caballero-Villarraso, Gustavo Ferrín, Javier Briceño
Publikováno v:
Anti-cancer agents in medicinal chemistry. 19(11)
Background: Parallel to the safety of liver resections, new chemotherapy drugs have emerged for the control of liver metastases. However, there is unclear evidence about the combination of intensive BVZ-therapy and extended resections. The main aim w
Autor:
José Luis Montero-Álvarez, Clara I. Linares, Sandra González-Rubio, Patricia Aguilar-Melero, Antonio Rodríguez-Ariza, Marta Casado, Manuel Rodríguez-Perálvarez, Manuel de la Mata, Ana Julia Fernández-Alvarez, Rafael Sánchez-Sánchez, Gustavo Ferrín, Laura M. López-Sánchez, Juan R. Muñoz-Castañeda, Jordi Muntané
Publikováno v:
Biochemical Pharmacology. 96:39-51
During the course of cholestatic liver diseases, the toxic effect of bile acids accumulation has been related to the decreased expression of endothelial nitric oxide synthase (NOS-3) and cellular oxidative stress increase. In the present study, we ha
Autor:
Jordi Muntané, Manuel de la Mata, Manuel Rodríguez-Perálvarez, José Luis Montero-Álvarez, Clara I. Linares, Gustavo Ferrín, Patricia Aguilar-Melero, Eduardo Chicano-Gálvez, José M. Cuezva, María Sánchez-Aragó, Sandra González-Rubio
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
© 2015 Elsevier B.V. Stable overexpression of endothelial nitric oxide synthase (NOS-3) in HepG2 cells (4TO-NOS) leads to increased nitro-oxidative stress and upregulation of the cell death mediators p53 and Fas. Thus, NOS-3 overexpression has been
Autor:
Patricia Aguilar-Melero, Manuel de la Mata, Clara I. Linares, Gustavo Ferrín, José Luis Montero-Álvarez, Manuel Rodríguez-Perálvarez, Sandra González-Rubio
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160525 (2016)
PLoS ONE
PLoS ONE
The harmful effects of bile acid accumulation occurring during cholestatic liver diseases have been associated with oxidative stress increase and endothelial nitric oxide synthase (NOS-3) expression decrease in liver cells. We have previously reporte
Publikováno v:
Current Pharmaceutical Design. 17:2002-2016
Mitochondria are involved in different physiological and pathological processes that are crucial for tumor cell physiology, growth and survival. Since cancer cells have frequently disrupted different cell death pathways that promote their survival, m