Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Clara Henriquez"'
Autor:
Charless C Fowlkes, Kelly B Eckenrode, Meghan D Bragdon, Miriah Meyer, Zeba Wunderlich, Lisa Simirenko, Cris L Luengo Hendriks, Soile V E Keränen, Clara Henriquez, David W Knowles, Mark D Biggin, Michael B Eisen, Angela H DePace
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002346 (2011)
Differences in the level, timing, or location of gene expression can contribute to alternative phenotypes at the molecular and organismal level. Understanding the origins of expression differences is complicated by the fact that organismal morphology
Externí odkaz:
https://doaj.org/article/7df817c0d1ba41f1981d6ea5d2f6871a
Autor:
Clara Henriquez, Hamutal Arbel, Mark D. Biggin, Susan E. Celniker, Kenneth H. Wan, James B. Brown, Sumanta Basu, Soo Park, Peter J. Bickel, Richard Weiszmann, Benjamin W. Booth, Ann S. Hammonds, Omid Shams Solari, William W. Fisher, Soile V.E. Keranen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 3
Proceedings of the National Academy of Sciences of the United States of America
Arbel, H; Basu, S; Fisher, WW; Hammonds, AS; Wan, KH; Park, S; et al.(2019). Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy. Proceedings of the National Academy of Sciences of the United States of America, 116(3), 900-908. doi: 10.1073/pnas.1808833115. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/6jt200hj
Proceedings of the National Academy of Sciences of the United States of America
Arbel, H; Basu, S; Fisher, WW; Hammonds, AS; Wan, KH; Park, S; et al.(2019). Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy. Proceedings of the National Academy of Sciences of the United States of America, 116(3), 900-908. doi: 10.1073/pnas.1808833115. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/6jt200hj
Significance We demonstrate a high-accuracy method for predicting enhancers genome-wide with >85% precision as validated by transgenic reporter assays in Drosophila embryos. This accuracy in a metazoan system enables us to predict with high confidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a35a0f230f22332bdb66c91afb2e914
https://escholarship.org/uc/item/6jt200hj
https://escholarship.org/uc/item/6jt200hj
Autor:
Richard Weiszmann, Soo Park, Clara Henriquez, Hamutal Arbel, Peter J. Bickel, Omid Shams Solari, Susan E. Celniker, Kenneth H. Wan, Mark D. Biggin, James B. Brown, Soile V.E. Keranen, William W. Fisher, Ann S. Hammonds
Identifying functional enhancers elements in metazoan systems is a major challenge. For example, large-scale validation of enhancers predicted by ENCODE reveal false positive rates of at least 70%. Here we use the pregrastrula patterning network ofDr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e815b9560030612aff673afc2fac389d
Autor:
Cris L, Luengo Hendriks, Soile V E, Keränen, Charless C, Fowlkes, Lisa, Simirenko, Gunther H, Weber, Angela H, DePace, Clara, Henriquez, David W, Kaszuba, Bernd, Hamann, Michael B, Eisen, Jitendra, Malik, Damir, Sudar, Mark D, Biggin, David W, Knowles
Publikováno v:
Genome Biology
A suite of methods that provide the first quantitative three-dimensional description of gene expression and morphology with cellular resolution in whole Drosophila embryos is described.
Background To model and thoroughly understand animal transc
Background To model and thoroughly understand animal transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::620f365f5f4a60e2ac5ca4f5a6d3bf4d
https://pubmed.ncbi.nlm.nih.gov/17184546
https://pubmed.ncbi.nlm.nih.gov/17184546
Autor:
Clara Henriquez, Lisa Simirenko, Cris L. Luengo Hendriks, Miriah Meyer, David W. Knowles, Kelly B. Eckenrode, Angela H. DePace, Meghan D. J. Bragdon, Zeba Wunderlich, Charless C. Fowlkes, Soile V.E. Keranen, Michael B. Eisen, Mark D. Biggin
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002346 (2011)
PLoS Genetics
PLoS Genetics
Differences in the level, timing, or location of gene expression can contribute to alternative phenotypes at the molecular and organismal level. Understanding the origins of expression differences is complicated by the fact that organismal morphology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25210e9992ded983e7737a286ec5ad20
https://doi.org/10.1371/journal.pgen.1002346
https://doi.org/10.1371/journal.pgen.1002346