Redox Imbalance in Lung Cancer of Patients with Underlying Chronic Respiratory Conditions

Autor: Mercè Mateu-Jiménez, Albert Sánchez-Font, Alberto Rodríguez-Fuster, Rafael Aguiló, Lara Pijuan, Clara Fermoselle, Joaquim Gea, Víctor Curull, Esther Barreiro

Publikováno v: Molecular Medicine, Vol 22, Iss 1, Pp 85-98 (2016)

Abstract Chronic respiratory diseases such as obstructive pulmonary disease (COPD) and oxidative stress may underlie lung cancer (LC). We hypothesized that the profile of oxidative and antioxidant events may differ in lung tumors and blood compartmen

Externí odkaz: https://doaj.org/article/ab1993e643b1484ca95e3ddb73d2ee4a

Role of PARP activity in lung cancer-induced cachexia: effects on muscle oxidative stress, proteolysis, anabolic markers, and phenotype

Autor: Esther Barreiro, Clara Fermoselle, Klaus Langohr, Alba Chacon-Cabrera, José Yélamos, Antoni L. Andreu, Elena García-Arumí, Mercè Mateu-Jimenez

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Recercat. Dipósit de la Recerca de Catalunya
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This is the peer reviewed version of the following article: Chacon, A., Mateu Jimenez, M., Langohr, K., Fermoselle, C., García Arumí, E., Andreu, A., Yelamos, J., Barreiro, E. Role of PARP activity in lung cancer-induced cachexia: effects on muscle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e187dd7d06dc7849b849014f49dbfe7
http://hdl.handle.net/2117/114680

Mitochondrial dysfunction and therapeutic approaches in respiratory and limb muscles of cancer cachectic mice

Autor: Luis Puente-Maestu, Alberto Tejedor, Ester Puig-Vilanova, Alejandro J. Urtreger, Clara Fermoselle, Esther Barreiro, Elena García-Arumí, Antoni L. Andreu, Elisa Bal de Kier Joffé

Publikováno v: Experimental Physiology. 98:1349-1365

New Findings • What is the central question of this study? We explored whether experimental cancer-induced cachexia may alter mitochondrial respiratory chain (MRC) complexes and oxygen uptake in respiratory and peripheral muscles, and whether signa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db3c282bc0fc1b286284403fefc75b39
https://doi.org/10.1113/expphysiol.2013.072496

Reduction of Muscle Mass Mediated by Myostatin in an Experimental Model of Pulmonary Emphysema

Autor: Francisco Sanchez, Clara Fermoselle, Esther Barreiro

Publikováno v: Archivos de Bronconeumología (English Edition). 47:590-598

a b s t r a c t Introduction: Among the extrapulmonary manifestations of COPD, dysfunction and loss of muscle mass/weight are those that have the greatest impact on the quality of life of patients. Our objective was to evaluate the molecular mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02697ad559f75bc964d17eceb9c4bef8
https://doi.org/10.1016/j.arbr.2011.11.002

MicroRNA expression and protein acetylation pattern in respiratory and limb muscles of Parp-1(-/-) and Parp-2(-/-) mice with lung cancer cachexia

Autor: Esther Barreiro, Alba Chacon-Cabrera, Ida Salmela, Clara Fermoselle, José Yélamos

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname

BACKGROUND: Current treatment options for cachexia, which impairs disease prognosis, are limited. Muscle-enriched microRNAs and protein acetylation are involved in muscle wasting including lung cancer (LC) cachexia. Poly(ADP-ribose) polymerases (PARP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f542e224077a0bc9edcc4562dcbba82e
https://pubmed.ncbi.nlm.nih.gov/26432600