Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Clara C. Lowe"'
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110199- (2024)
Summary: Neurons in the neocortex are generated during embryonic development. While the adult ventricular-subventricular zone (V-SVZ) contains cells with neural stem/progenitors’ characteristics, it remains unclear whether it has the capacity of pr
Externí odkaz:
https://doaj.org/article/380dbaca531c4577bcbe42b4ee7c9655
Autor:
Yan Guo, Alison.A. Chomiak, Ye Hong, Clara C. Lowe, Caroline A. Kopsidas, Wen-Ching Chan, Jorge Andrade, Hongna Pan, Xiaoming Zhou, Edwin S. Monuki, Yuanyi Feng
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104519- (2022)
Summary: Aging is an intricate process characterized by multiple hallmarks including stem cell exhaustion, genome instability, epigenome alteration, impaired proteostasis, and cellular senescence. Whereas each of these traits is detrimental at the ce
Externí odkaz:
https://doaj.org/article/600df9637a5a4198b6f7f28e33a479b5
Autor:
Alison A. Chomiak, Yan Guo, Caroline A. Kopsidas, Dennis P. McDaniel, Clara C. Lowe, Hongna Pan, Xiaoming Zhou, Qiong Zhou, Martin L. Doughty, Yuanyi Feng
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104354- (2022)
Summary: The NDE1 gene encodes a scaffold protein essential for brain development. Although biallelic NDE1 loss of function (LOF) causes microcephaly with profound mental retardation, NDE1 missense mutations and copy number variations are associated
Externí odkaz:
https://doaj.org/article/241d88fc941543558b66597fdeea1857
DNA double strand breaks (DSBs), neuroinflammation, and vascular alterations in the brain are all associated with neurodegenerative disorders. However, the interconnections between these neuropathological changes and how they act synergistically to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c04c54af2fb153d3cd262075f9f186ac
https://doi.org/10.1101/2023.01.26.525738
https://doi.org/10.1101/2023.01.26.525738
Autor:
Qiong Zhou, Yingni Guo, Dennis P. McDaniel, Clara C. Lowe, Alison A. Chomiak, Hongna Pan, Yuanyi Feng, Martin L. Doughty, Xiaoming Zhou
Publikováno v:
iScience. 25:104354
SUMMARYTheNDE1gene encodes a scaffold protein essential for brain development. While biallelicNDE1loss of function (LOF) causes microcephaly with profound mental retardation,NDE1missense mutations and copy number variations are associated with multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e5eb887def0682210d73eed47ed262
https://doi.org/10.1016/j.isci.2022.104354
https://doi.org/10.1016/j.isci.2022.104354
Autor:
Alison Chomiak, Clara C. Lowe, Yan Guo, Hongna Pan, Dennis McDaniel, Xiaoming Zhou, Qiong Zhou, Martin L. Doughty, Yuanyi Feng
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb2230b87e8585f3bc06969517a750c2
https://doi.org/10.2139/ssrn.3937607
https://doi.org/10.2139/ssrn.3937607
Autor:
Jorge Andrade, Edwin S. Monuki, Eugene Berezovski, Clara C. Lowe, Wen-Ching Chan, Yuanyi Feng, Yan Guo, Hongna Pan, Alison A. Chomiak, Ye Hong, Xiaoming Zhou
Publikováno v:
SSRN Electronic Journal.
SUMMARYAging is an intricate process that is characterized by multiple hallmarks including stem cell exhaustion, genome instability, epigenome alteration, impaired proteostasis, and cellular senescence. While each of these traits is detrimental at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b508177c1e5c04aa8abb33d143ea5499
https://doi.org/10.2139/ssrn.3937606
https://doi.org/10.2139/ssrn.3937606