Tetralol derivative NNC-55-0396 targets hypoxic cells in the glioblastoma microenvironment: an organ-on-chip approach

Autor: Clara Bayona, Lía Alza, Teodora Ranđelović, Marta C. Sallán, Anna Visa, Carles Cantí, Ignacio Ochoa, Sara Oliván, Judit Herreros

Publikováno v: Cell Death and Disease, Vol 15, Iss 2, Pp 1-8 (2024)

Abstract Glioblastoma (GBM) is a highly malignant brain tumour characterised by limited treatment options and poor prognosis. The tumour microenvironment, particularly the central hypoxic region of the tumour, is known to play a pivotal role in GBM p

Externí odkaz: https://doaj.org/article/e4a3f5b50b37495b857d31489a765008

Descifrando el Glioblastoma: simulando el microentorno tumoral para la detección de nuevos biomarcadores utilizando modelos Organ-on-Chip

Autor: Clara Bayona

Publikováno v: Jornada de Jóvenes Investigadores del I3A. 10

La elevada heterogeneidad y las limitaciones en las técnicas de diagnóstico del Glioblastoma (GBM) ponen de manifiesto la necesidad de desarrollar modelos celulares más complejos que permitan recrear la heterogeneidad tumoral y faciliten la identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::865a79a2909533bfda8a1050fa600093
https://doi.org/10.26754/jjii3a.20227058

Self-Powered Detection of Glucose by Enzymatic Glucose/Oxygen Fuel Cells on Printed Circuit Boards

Autor: Dónal Leech, Carla Gonzalez-Solino, Clara Bayona Royo, Elena Bernalte, Richard Bennett, Mirella Di Lorenzo

Publikováno v: ACS Applied Materials & Interfaces
Gonzalez-Solino, C, Bernalte, E, Bayona Royo, C, Bennett, R, Leech, D & Di Lorenzo, M 2021, ' Self-Powered Detection of Glucose by Enzymatic Glucose/Oxygen Fuel Cells on Printed Circuit Boards ', ACS Applied Materials and Interfaces, vol. 13, no. 23, pp. 26704-26711 . https://doi.org/10.1021/acsami.1c02747

Monitoring glucose levels in physiological fluids can help prevent severe complications associated with hypo- and hyper-glycemic events. Current glucose-monitoring systems require a three-electrode setup and a power source to function, which can hamp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae26cdf5bac7fc01356870b8caf8960
http://europepmc.org/articles/PMC8735749